Kinase Profiling Inhibitor Database

Inhibitor Structure Image Brutto MW Action Reference Reference 2 Patent Commercial Vendor Notes Results
SB-216763 C19H12Cl2N2O2 371.22 GSK3 Coghlan (2000) Chem.Biol. 7 793 Liang (2006) J.Biol.Chem. 282 3904 Tocris Download

Results as Barchart

View results as a bar chart
10µM

Results as Table

Screening Concentration: 10µM
Kinase % Activity Remaining Standard Deviation
MKK1 61 4
ERK1 88 13
ERK2 76 5
JNK1 95 5
JNK2 81 1
JNK3 77 6
p38 alpha MAPK 72 3
p38 beta MAPK 61 12
p38 gamma MAPK 95 5
p38 delta MAPK 67 11
ERK8 0 0
RSK1 33 0
RSK2 40 2
PDK1 95 2
PKB alpha 84 7
PKB beta 81 14
SGK1 84 2
S6K1 96 10
PKA 92 5
ROCK 2 71 6
PRK2 69 1
PKC alpha 58 7
PKC zeta 75 6
PKD1 86 12
MSK1 73 4
MNK1 79 1
MNK2 81 4
MAPKAP-K2 71 10
MAPKAP-K3 117 3
PRAK 84 3
CAMKK alpha 85 3
CAMKK beta 43 12
CAMK1 86 3
SmMLCK 40 6
PHK 73 5
CHK1 92 8
CHK2 83 7
GSK3 beta -3 1
CDK2-Cyclin A 57 9
PLK1 51 2
Aurora B 83 4
Aurora C 52 1
AMPK 69 0
MARK3 68 10
BRSK2 82 4
MELK 59 3
CK1 delta 73 5
CK2 91 6
DYRK1A 4 0
DYRK2 104 3
DYRK3 59 1
NEK2a 60 7
NEK6 42 8
NEK7 79 1
IKK beta 91 0
IKK epsilon 55 4
TBK1 82 8
PIM1 62 11
PIM2 44 3
PIM3 31 5
SRPK1 12 2
EF2K 96 4
HIPK2 14 7
HIPK3 41 4
PAK4 63 4
PAK5 58 1
PAK6 86 14
MST2 31 7
MST4 49 7
Src 85 6
Lck 88 11
CSK 91 1
YES1 43 11
SYK 89 13
EPH-A2 84 4
FGF-R1 94 11
IRR 31 3

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