Kinase Profiling Inhibitor Database

Inhibitor Structure Image Brutto MW Action Reference Reference 2 Patent Commercial Vendor Notes Results
Resveratrol C14H12O3 228.2 cyclo-oxygenase 1 Lin H.Y. (2002) J. Urol. 168 748 Klabunde T. (2000) Nat. Struct. Biol. 7 312 Merck (Calbiochem) Download

Results as Barchart

View results as a bar chart
1µM
50µM
10µM

Results as Table

Screening Concentration: 50µM
Kinase % Activity Remaining Standard Deviation
MKK1 75 3
ERK1 92 0
ERK2 100 2
JNK1 101 7
JNK2 103 5
JNK3 114 15
p38 alpha MAPK 75 4
p38 beta MAPK 108 10
p38 gamma MAPK 65 2
p38 delta MAPK 72 9
ERK8 12 4
RSK1 15 1
RSK2 18 0
PDK1 56 11
PKB alpha 63 11
PKB beta 76 11
SGK1 23 1
S6K1 15 1
PKA 91 2
ROCK 2 21 7
PRK2 21 6
PKC alpha 58 3
PKC zeta 99 4
PKD1 51 0
MSK1 16 6
MNK1 125 1
MNK2 34 8
MAPKAP-K2 71 9
MAPKAP-K3 97 13
PRAK 56 5
CAMKK alpha 30 3
CAMKK beta 28 6
CAMK1 38 9
SmMLCK 15 5
PHK 23 7
CHK1 29 8
CHK2 14 0
GSK3 beta 37 1
CDK2-Cyclin A 34 5
PLK1 78 9
Aurora B 22 2
Aurora C 32 1
AMPK 16 1
MARK3 41 9
BRSK2 13 2
MELK 8 3
CK1 delta 46 2
CK2 49 0
DYRK1A 17 0
DYRK2 1 0
DYRK3 2 0
NEK2a 83 5
NEK6 87 2
NEK7 95 3
IKK beta 46 2
PIM1 4 0
PIM2 27 8
PIM3 2 0
SRPK1 93 5
EF2K 87 3
HIPK2 3 0
HIPK3 12 0
PAK4 67 5
PAK5 75 3
PAK6 100 3
MST2 28 2
Src 47 2
Lck 59 9
CSK 68 1
Screening Concentration: 10µM
Kinase % Activity Remaining Standard Deviation
MKK1 81 9
MKK2 91 4
MKK6 87 9
ERK1 88 10
ERK2 79 1
JNK1 108 5
JNK2 86 12
JNK3 87 8
p38 alpha MAPK 97 6
p38 beta MAPK 93 3
p38 gamma MAPK 78 6
p38 delta MAPK 91 2
ERK8 10 1
RSK1 63 1
RSK2 72 3
PDK1 97 4
PKB alpha 89 5
PKB beta 67 13
SGK1 94 3
S6K1 69 10
PKA 101 5
ROCK 2 83 2
PRK2 70 6
PKC alpha 82 3
PKC zeta 105 1
PKD1 105 8
MSK1 65 7
MNK1 66 6
MNK2 96 10
MAPKAP-K2 88 3
MAPKAP-K3 64 2
PRAK 85 1
CAMKK beta 74 6
CAMK1 73 7
SmMLCK 63 8
PHK 21 4
DAPK1 62 0
CHK1 79 2
CHK2 79 13
GSK3 beta 80 5
CDK2-Cyclin A 59 3
PLK1 87 2
Aurora A 100 11
Aurora B 62 11
LKB1 69 2
AMPK 73 7
MARK1 96 3
MARK2 86 3
MARK3 82 4
MARK4 99 6
BRSK1 56 5
BRSK2 50 9
MELK 50 6
NUAK1 68 5
CK1 delta 94 8
CK2 82 6
DYRK1A 61 8
DYRK2 15 2
DYRK3 8 0
NEK2a 91 1
NEK6 96 3
IKK beta 70 1
IKK epsilon 59 2
TBK1 79 2
PIM1 30 5
PIM2 37 3
PIM3 44 2
SRPK1 87 12
EF2K 69 11
HIPK1 48 8
HIPK2 30 11
HIPK3 41 3
CLK2 55 4
PAK2 83 2
PAK4 80 7
PAK5 83 3
PAK6 106 8
MST2 69 9
MST4 68 5
GCK 73 0
MINK1 66 8
MEKK1 90 10
MLK1 44 3
MLK3 35 2
TAO1 32 1
ASK1 77 2
TAK1 83 1
IRAK4 73 3
RIPK2 51 0
TTK 83 3
Src 81 6
Lck 97 7
CSK 87 3
YES1 77 3
BTK 75 2
JAK2 27 2
SYK 92 14
EPH-A2 81 8
EPH-A4 107 5
EPH-B1 97 13
EPH-B2 116 7
EPH-B3 88 12
EPH-B4 99 6
FGF-R1 85 3
HER4 59 3
IGF-1R 59 5
IR 50 10
IRR 62 2
TrkA 67 8
VEGFR1 51 5
Screening Concentration: 1µM
Kinase % Activity Remaining Standard Deviation
MKK1 99 6
ERK1 101 11
ERK2 102 9
JNK1 96 10
JNK2 95 10
JNK3 80 8
p38 alpha MAPK 95 6
p38 beta MAPK 112 2
p38 gamma MAPK 106 8
p38 delta MAPK 95 6
ERK8 36 6
RSK1 77 0
RSK2 77 8
PDK1 74 6
PKB alpha 82 6
PKB beta 108 8
SGK1 79 3
S6K1 93 9
PKA 106 6
ROCK 2 125 3
PRK2 95 9
PKC alpha 96 3
PKC zeta 128 12
PKD1 96 2
MSK1 80 0
MNK1 102 13
MNK2 74 0
MAPKAP-K2 118 9
MAPKAP-K3 121 12
PRAK 105 8
CAMKK alpha 98 1
CAMKK beta 107 2
CAMK1 75 9
SmMLCK 78 9
PHK 58 13
CHK1 95 5
CHK2 84 6
GSK3 beta 100 1
CDK2-Cyclin A 103 9
PLK1 90 9
Aurora B 97 8
Aurora C 75 2
AMPK 103 9
MARK3 99 2
BRSK2 54 5
MELK 49 3
CK1 delta 84 6
CK2 101 1
DYRK1A 94 6
DYRK2 40 5
DYRK3 38 2
NEK2a 96 1
NEK6 104 9
NEK7 94 9
IKK beta 99 0
PIM1 50 10
PIM2 78 9
PIM3 48 1
SRPK1 111 1
EF2K 95 8
HIPK2 60 0
HIPK3 93 11
PAK4 85 8
PAK5 102 0
PAK6 108 1
MST2 84 9
Src 108 2
Lck 115 8
CSK 102 9

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