Kinase Profiling Inhibitor Database

Inhibitor Structure Image Brutto MW Action Reference Reference 2 Patent Commercial Vendor Notes Results
PS-1145 C17H11ClN4O 322.75 IKK Castro A.C. (2003) Bioorg. Med. Chem. Lett. 13 2419-2422. WO2003039545 Sigma Download

Results as Barchart

View results as a bar chart
10µM

Results as Table

Screening Concentration: 10µM
Kinase % Activity Remaining Standard Deviation
MKK1 83 1
ERK1 106 8
ERK2 84 3
JNK1 86 4
JNK2 93 1
JNK3 92 0
p38 alpha MAPK 89 4
p38 beta MAPK 84 6
p38 gamma MAPK 98 4
p38 delta MAPK 78 7
ERK8 42 6
RSK1 66 1
RSK2 82 4
PDK1 87 3
PKB alpha 90 1
PKB beta 101 9
SGK1 75 0
S6K1 86 1
PKA 86 8
ROCK 2 69 6
PRK2 71 7
PKC alpha 77 2
PKC zeta 78 6
PKD1 108 4
MSK1 99 1
MNK1 44 2
MNK2 70 2
MAPKAP-K2 83 4
MAPKAP-K3 95 9
PRAK 85 5
CAMKK alpha 80 1
CAMKK beta 69 8
CAMK1 73 1
SmMLCK 88 1
PHK 85 7
CHK1 90 5
CHK2 102 8
GSK3 beta 46 6
CDK2-Cyclin A 76 0
PLK1 98 6
Aurora B 70 6
Aurora C 80 6
AMPK 88 4
MARK3 89 4
BRSK2 90 1
MELK 70 1
CK1 delta 92 1
CK2 87 1
DYRK1A 47 2
DYRK2 89 1
DYRK3 50 3
NEK2a 85 6
NEK6 83 1
NEK7 103 4
IKK beta 4 0
IKK epsilon 81 3
TBK1 87 1
PIM1 13 1
PIM2 47 1
PIM3 9 1
SRPK1 88 2
EF2K 100 2
HIPK2 67 3
HIPK3 89 2
PAK4 93 1
PAK5 87 2
PAK6 101 0
MST2 88 7
Src 98 5
Lck 57 3
CSK 83 1

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