Kinase Profiling Inhibitor Database

Inhibitor Structure Image Brutto MW Action Reference Reference 2 Patent Commercial Vendor Notes Results
Piceatannol C14H12O4 244.2 PKA, SYK Wang B.H. (1998) Planta Med. 64 195 Keely P.J. and Parise L.V. (1996) J. Biol. Chem. 271 26668 WO2012021964 Merck (Calbiochem) Download

Results as Barchart

View results as a bar chart
1µM
10µM

Results as Table

Screening Concentration: 1µM
Kinase % Activity Remaining Standard Deviation
MKK1 89 10
MKK2 109 3
MKK6 99 1
ERK1 113 7
ERK2 109 7
JNK1 104 2
JNK2 112 5
JNK3 96 2
p38 alpha MAPK 73 0
p38 beta MAPK 95 7
p38 gamma MAPK 113 1
p38 delta MAPK 93 5
ERK8 90 7
RSK1 93 2
RSK2 115 3
PDK1 99 8
PKB alpha 91 6
PKB beta 70 10
SGK1 109 10
S6K1 92 1
PKA 106 2
ROCK 2 66 3
PRK2 86 6
PKC alpha 114 11
PKC zeta 108 2
PKD1 101 2
MSK1 105 12
MNK1 98 4
MNK2 108 0
MAPKAP-K2 85 3
MAPKAP-K3 119 10
PRAK 110 13
CAMKK beta 111 10
CAMK1 108 4
SmMLCK 81 11
PHK 102 13
DAPK1 89 3
CHK1 88 3
CHK2 107 4
GSK3 beta 104 6
CDK2-Cyclin A 111 0
PLK1 125 6
Aurora A 99 4
Aurora B 96 7
LKB1 91 1
AMPK 126 2
MARK1 102 10
MARK2 87 4
MARK3 82 1
MARK4 98 4
BRSK1 73 5
BRSK2 83 2
MELK 121 11
NUAK1 79 13
CK1 delta 94 13
CK2 115 8
DYRK1A 76 7
DYRK2 70 4
DYRK3 101 12
NEK2a 77 2
NEK6 104 3
IKK beta 97 2
IKK epsilon 99 2
TBK1 113 6
PIM1 87 2
PIM2 102 8
PIM3 72 3
SRPK1 78 3
EF2K 117 0
HIPK1 98 5
HIPK2 99 2
HIPK3 91 3
CLK2 102 10
PAK2 101 6
PAK4 86 11
PAK5 103 15
PAK6 119 10
MST2 92 3
MST4 110 4
GCK 118 7
MINK1 111 8
MEKK1 103 10
MLK1 87 14
MLK3 84 8
TAO1 114 14
ASK1 101 9
TAK1 99 1
IRAK4 103 8
RIPK2 80 7
TTK 96 9
Src 81 5
Lck 108 3
CSK 108 10
YES1 110 6
BTK 101 11
JAK2 96 5
SYK 100 7
EPH-A2 103 4
EPH-A4 116 2
EPH-B1 120 12
EPH-B2 126 8
EPH-B3 104 5
EPH-B4 129 1
FGF-R1 100 5
HER4 96 2
IGF-1R 113 6
IR 61 10
IRR 86 1
TrkA 110 5
VEGFR1 100 12
Screening Concentration: 10µM
Kinase % Activity Remaining Standard Deviation
MKK1 87 3
MKK2 109 7
MKK6 101 10
ERK1 121 6
ERK2 98 1
JNK1 100 4
JNK2 111 1
JNK3 116 6
p38 alpha MAPK 77 7
p38 beta MAPK 114 15
p38 gamma MAPK 76 11
p38 delta MAPK 93 3
ERK8 64 1
RSK1 72 3
RSK2 65 7
PDK1 89 10
PKB alpha 89 10
PKB beta 51 7
SGK1 85 6
S6K1 87 6
PKA 101 2
ROCK 2 82 4
PRK2 88 7
PKC alpha 98 0
PKC zeta 51 2
PKD1 75 3
MSK1 86 8
MNK1 84 11
MNK2 96 3
MAPKAP-K2 102 13
MAPKAP-K3 92 1
PRAK 95 2
CAMKK beta 87 4
CAMK1 66 1
SmMLCK 40 0
PHK 71 1
DAPK1 69 3
CHK1 125 9
CHK2 69 5
GSK3 beta 87 5
CDK2-Cyclin A 107 2
PLK1 101 1
Aurora A 78 8
Aurora B 63 13
LKB1 58 6
AMPK 85 11
MARK1 69 5
MARK2 80 1
MARK3 51 3
MARK4 89 0
BRSK1 45 0
BRSK2 44 1
MELK 77 5
NUAK1 47 14
CK1 delta 88 3
CK2 100 1
DYRK1A 28 2
DYRK2 16 1
DYRK3 38 10
NEK2a 44 0
NEK6 105 8
IKK beta 86 1
IKK epsilon 60 2
TBK1 73 2
PIM1 25 2
PIM2 59 1
PIM3 31 1
SRPK1 52 1
EF2K 105 8
HIPK1 94 4
HIPK2 49 2
HIPK3 74 2
CLK2 32 3
PAK2 93 7
PAK4 62 8
PAK5 69 13
PAK6 80 6
MST2 37 6
MST4 75 13
GCK 78 6
MINK1 68 4
MEKK1 84 8
MLK1 32 3
MLK3 34 1
TAO1 82 4
ASK1 114 8
TAK1 102 7
IRAK4 87 8
RIPK2 69 3
TTK 72 2
Src 48 8
Lck 71 2
CSK 108 8
YES1 65 1
BTK 64 2
JAK2 72 5
SYK 113 5
EPH-A2 90 8
EPH-A4 108 4
EPH-B1 112 13
EPH-B2 97 14
EPH-B3 99 14
EPH-B4 57 3
FGF-R1 47 5
HER4 72 2
IGF-1R 105 5
IR 36 10
IRR 57 2
TrkA 76 2
VEGFR1 45 6

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