Kinase Profiling Inhibitor Database

Inhibitor Structure Image Brutto MW Action Reference Reference 2 Patent Commercial Vendor Notes Results
GW441756 hydrochloride C17H13N3O • HCl 311.77 Trk A Wood E.R. (2004) Bioorg. Med. Chem. Lett. 14 953-957 Sigma Download

Results as Barchart

View results as a bar chart
1µM

Results as Table

Screening Concentration: 1µM
Kinase % Activity Remainingsort descending Standard Deviation
VEGFR1 13 2
TrkA 14 1
IRAK4 15 1
TAK1 18 1
FGF-R1 20 3
MLK1 25 1
NUAK1 27 0
CLK2 30 2
MLK3 32 10
PIM3 33 1
HIPK1 33 7
CHK2 34 4
MST2 39 3
YES1 41 2
Aurora A 42 10
MKK2 42 4
JAK2 42 1
Lck 43 0
GCK 43 0
Src 44 2
MINK1 45 5
IR 45 16
MELK 46 15
RSK1 51 4
IRR 52 3
PHK 57 3
PIM1 59 12
ROCK 2 62 7
ABL 62 10
CAMKK beta 63 2
IGF-1R 63 6
GSK3 beta 63 17
HIPK2 63 0
ERK8 64 4
BTK 65 2
RSK2 66 4
BRSK1 66 3
MNK2 67 10
MKK1 67 1
BRSK2 67 2
RIPK2 68 1
DYRK2 69 6
SYK 72 10
PKD1 72 3
STK33 73 17
IRAK1 73 0
MAPKAP-K2 73 12
TBK1 73 3
Aurora B 74 4
SmMLCK 74 3
S6K1 76 13
CK1 delta 77 5
PAK4 77 3
EPH-A4 78 7
EPH-B1 78 1
MAPKAP-K3 78 4
BRK 80 0
ASK1 80 1
EPH-A2 81 2
MARK3 81 1
MARK4 81 14
MARK1 82 7
DAPK1 83 3
EPH-B4 84 8
CHK1 84 4
MSK1 85 14
EPH-B2 85 1
HER4 85 2
CSK 86 4
IKK beta 86 4
TTK 87 7
TIE2 87 21
MNK1 88 2
PDK1 88 2
PKB alpha 88 9
PRK2 88 13
NEK6 88 1
CK2 89 0
PIM2 89 3
ERK1 90 1
SGK1 92 2
DYRK1A 93 11
NEK2a 93 1
MST4 93 13
EIF2AK3 93 4
PAK2 94 7
OSR1 94 0
CAMK1 94 6
SRPK1 94 1
PKB beta 96 11
JNK3 96 2
EF2K 96 5
PKC gamma 96 29
AMPK 97 4
MEKK1 97 11
PKC zeta 97 12
IKK epsilon 98 8
p38 delta MAPK 99 4
PAK6 99 10
MPSK1 99 11
PRAK 99 3
LKB1 100 8
ZAP70 100 3
DYRK3 102 17
MKK6 102 2
p38 alpha MAPK 102 1
p38 beta MAPK 103 13
PLK1 104 10
JNK2 106 8
p38 gamma MAPK 106 10
PAK5 107 10
MARK2 108 25
ERK2 109 7
PKC alpha 109 10
EPH-B3 111 9
TLK1 112 11
JNK1 112 0
CDK2-Cyclin A 116 9
PKA 117 15
TAO1 120 9
HIPK3 126 1

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