Kinase Profiling Inhibitor Database

Inhibitor Structure Image Brutto MW Action Reference Reference 2 Patent Commercial Vendor Notes Results
IC261 C18H17NO4 311.3 CK1 Behrend L. (2000) Oncogene 19 5303 Mashhoon N. (2000) J. Biol. Chem. 275 20052 WO2008066626 Merck (Calbiochem) Download

Results as Barchart

View results as a bar chart
25µM

Results as Table

Screening Concentration: 25µM
Kinase % Activity Remaining Standard Deviation
MKK1 86 2
ERK1 91 6
ERK2 93 4
JNK1 94 2
JNK2 101 3
JNK3 93 4
p38 alpha MAPK 91 4
p38 beta MAPK 96 7
p38 gamma MAPK 92 4
p38 delta MAPK 91 4
ERK8 68 2
RSK1 87 3
RSK2 89 1
PDK1 89 5
PKB alpha 94 5
PKB beta 90 3
SGK1 79 4
S6K1 84 2
PKA 82 3
ROCK 2 78 0
PRK2 87 5
PKC alpha 90 2
PKC zeta 80 4
PKD1 62 3
MSK1 88 1
MNK1 79 3
MNK2 97 5
MAPKAP-K2 88 4
MAPKAP-K3 94 3
PRAK 82 5
CAMKK alpha 67 4
CAMKK beta 86 2
CAMK1 55 5
SmMLCK 70 2
PHK 86 1
CHK1 99 2
CHK2 76 4
GSK3 beta 74 6
CDK2-Cyclin A 83 4
PLK1 94 0
Aurora B 75 3
Aurora C 94 3
AMPK 71 2
MARK3 88 5
BRSK2 88 4
MELK 75 8
CK1 delta 9 2
CK2 97 2
DYRK1A 73 1
DYRK2 99 6
DYRK3 89 3
NEK2a 75 6
NEK6 95 5
NEK7 103 4
IKK beta 90 4
PIM1 43 1
PIM2 75 1
PIM3 41 1
SRPK1 95 1
EF2K 100 4
HIPK2 96 6
HIPK3 95 3
PAK4 84 2
PAK5 84 1
PAK6 76 0
MST2 70 1
Src 70 4
Lck 49 4
CSK 81 4

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