Kinase Profiling Inhibitor Database

Inhibitor Structure Image Brutto MW Action Reference Reference 2 Patent Commercial Vendor Notes Results
Harmine C13H12N2O 212.25 serotonin, monoamine oxidase Song Y. (2004) Biochem. Biophys. Res. Commun. 317 128–132 US5256533 Sigma Download

Results as Barchart

View results as a bar chart
1µM
10µM

Results as Table

Screening Concentration: 1µM
Kinase % Activity Remaining Standard Deviation
MKK1 98 1
ERK1 107 44
ERK2 89 7
JNK1 100 14
JNK2 92 10
JNK3 77 0
p38 alpha MAPK 89 1
p38 beta MAPK 106 23
p38 gamma MAPK 89 10
p38 delta MAPK 111 0
ERK8 77 11
RSK1 114 13
RSK2 91 2
PDK1 101 7
PKB alpha 91 7
PKB beta 103 8
SGK1 90 3
S6K1 93 1
PKA 94 4
ROCK 2 97 7
PRK2 91 9
PKC alpha 105 5
PKC zeta 103 13
PKD1 83 2
MSK1 90 3
MNK1 81 2
MNK2 84 7
MAPKAP-K2 87 8
MAPKAP-K3 97 5
PRAK 91 3
CAMKK alpha 87 1
CAMKK beta 96 6
CAMK1 100 3
SmMLCK 85 2
PHK 95 13
CHK1 88 3
CHK2 69 0
GSK3 beta 95 15
CDK2-Cyclin A 81 8
PLK1 103 4
Aurora B 82 1
Aurora C 83 1
AMPK 83 16
MARK3 112 17
BRSK2 107 8
MELK 79 8
CK1 delta 82 9
CK2 89 18
DYRK1A 9 0
DYRK2 28 3
DYRK3 33 9
NEK2a 96 4
NEK6 91 8
NEK7 107 1
IKK beta 105 4
IKK epsilon 92 11
TBK1 98 1
PIM1 84 0
PIM2 113 10
PIM3 79 6
SRPK1 82 12
EF2K 102 9
HIPK2 69 6
HIPK3 87 7
PAK4 82 10
PAK5 117 5
PAK6 106 4
MST2 93 2
MST4 97 5
Src 83 5
Lck 96 16
CSK 109 10
YES1 87 16
BTK 91 5
SYK 91 34
EPH-A2 101 0
EPH-B3 105 15
FGF-R1 105 8
IGF-1R 104 4
IR 105 4
IRR 37 0
VEGFR1 108 0
Screening Concentration: 10µM
Kinase % Activity Remaining Standard Deviation
MKK1 73 4
ERK1 95 5
ERK2 95 5
JNK1 89 3
JNK2 91 5
JNK3 91 0
p38 alpha MAPK 100 7
p38 beta MAPK 103 4
p38 gamma MAPK 80 3
p38 delta MAPK 88 1
ERK8 80 1
RSK1 105 6
RSK2 104 3
PDK1 87 1
PKB alpha 101 7
PKB beta 90 1
SGK1 83 1
S6K1 93 3
PKA 80 9
ROCK 2 80 4
PRK2 86 4
PKC alpha 82 4
PKC zeta 83 1
PKD1 80 9
MSK1 83 5
MNK1 82 4
MNK2 80 4
MAPKAP-K2 110 4
MAPKAP-K3 98 6
PRAK 90 2
CAMKK alpha 95 4
CAMKK beta 81 1
CAMK1 94 4
SmMLCK 87 7
PHK 85 5
CHK1 99 9
CHK2 100 0
GSK3 beta 87 0
CDK2-Cyclin A 86 4
PLK1 97 1
Aurora B 81 2
Aurora C 83 1
AMPK 72 1
MARK3 83 3
BRSK2 83 3
MELK 80 2
CK1 delta 60 4
CK2 68 5
DYRK1A 2 2
DYRK2 15 0
DYRK3 6 0
NEK2a 94 1
NEK6 87 1
NEK7 108 1
IKK beta 73 9
IKK epsilon 87 15
TBK1 89 1
PIM1 86 1
PIM2 88 7
PIM3 64 1
SRPK1 85 7
EF2K 104 8
HIPK2 108 7
HIPK3 87 8
PAK4 96 3
PAK5 92 5
PAK6 83 5
MST2 85 7
MST4 90 1
Src 88 9
Lck 81 2
CSK 86 3
YES1 83 21
BTK 84 10
SYK 85 16
EPH-A2 107 0
EPH-B3 105 21
FGF-R1 120 26
IGF-1R 106 42
IR 100 2
IRR 33 10
VEGFR1 95 3

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