Kinase Profiling Inhibitor Database

Inhibitor Structure Image Brutto MW Action Reference Reference 2 Patent Commercial Vendor Notes Results
H-8, Dihydrochloride C12H15N3O2S • 2HCl 338.3 serine/threonine kinases Ido M. (1991) Br. J. Cancer 64 1103 Hagiwara M. (1987) Mol. Pharmacol. 31 523 WO1999041984 Merck (Calbiochem) Download

Results as Barchart

View results as a bar chart
10µM

Results as Table

Screening Concentration: 10µM
Kinase % Activity Remainingsort descending Standard Deviation
PRK2 7 1
ROCK 2 13 0
RSK1 18 2
AMPK 19 0
PKA 22 1
MELK 23 0
MSK1 32 0
DYRK3 34 3
PKD1 39 1
RSK2 39 6
PKB alpha 40 2
BRSK2 42 8
GSK3 beta 42 1
S6K1 46 4
MST2 51 7
CDK2-Cyclin A 52 6
PHK 54 2
PKC alpha 54 3
PKB beta 59 1
PKC zeta 61 1
MNK1 63 0
PRAK 63 4
PIM3 65 4
MKK1 67 9
SGK1 70 7
MARK3 71 7
Aurora C 72 2
Lck 72 1
CSK 75 1
CAMKK beta 76 6
PLK1 77 0
CHK1 77 5
PIM1 79 3
Aurora B 79 7
MNK2 79 0
SmMLCK 79 9
CAMKK alpha 80 8
PAK5 80 8
p38 delta MAPK 82 1
CK2 83 5
PDK1 84 6
NEK6 85 4
CK1 delta 86 4
ERK8 87 5
ERK1 87 1
IKK beta 88 5
JNK2 88 5
DYRK1A 90 3
PAK6 91 2
MAPKAP-K3 92 8
PAK4 92 1
JNK1 92 3
SRPK1 94 6
Src 94 1
NEK2a 94 7
DYRK2 95 4
ERK2 95 4
HIPK3 98 2
CAMK1 98 7
HIPK2 101 4
p38 gamma MAPK 103 0
NEK7 104 1
JNK3 107 0
p38 beta MAPK 108 2
PIM2 111 8
p38 alpha MAPK 114 6
CHK2 114 1
MAPKAP-K2 115 1
EF2K 119 11

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