Kinase Profiling Inhibitor Database

Inhibitor Structure Image Brutto MW Action Reference Reference 2 Patent Commercial Vendor Notes Results
H-7, Dihydrochloride C14H17N3O2S • 2HCl 364.3 serine/threonine kinases Ku W.C. (1997) Biochem. Biophys. Res. Commun. 241 730 Jarvis W.D. (1994) Cancer Res. 54 1707 WO1999041984 Merck (Calbiochem) Download

Results as Barchart

View results as a bar chart
10µM

Results as Table

Screening Concentration: 10µM
Kinase % Activity Remaining Standard Deviation
MKK1 87 2
ERK1 105 2
ERK2 92 2
JNK1 90 1
JNK2 85 1
JNK3 85 0
p38 alpha MAPK 85 2
p38 beta MAPK 109 6
p38 gamma MAPK 97 0
p38 delta MAPK 82 3
ERK8 84 1
RSK1 16 0
RSK2 38 7
PDK1 78 3
PKB alpha 100 5
PKB beta 81 4
SGK1 84 0
S6K1 90 7
PKA 48 0
ROCK 2 15 1
PRK2 7 1
PKC alpha 48 3
PKC zeta 65 4
PKD1 37 3
MSK1 36 4
MNK1 67 4
MNK2 80 0
MAPKAP-K2 82 0
MAPKAP-K3 105 1
PRAK 97 0
CAMKK alpha 69 1
CAMKK beta 85 6
CAMK1 64 7
SmMLCK 86 2
PHK 68 7
CHK1 84 6
CHK2 110 2
GSK3 beta 64 4
CDK2-Cyclin A 52 2
PLK1 83 2
Aurora B 75 4
Aurora C 61 3
AMPK 24 0
MARK3 93 1
BRSK2 64 2
MELK 35 3
CK1 delta 86 0
CK2 89 2
DYRK1A 85 9
DYRK2 92 3
DYRK3 63 2
NEK2a 85 1
NEK6 102 8
NEK7 104 2
IKK beta 71 5
PIM1 94 11
PIM2 87 2
PIM3 68 0
SRPK1 91 0
EF2K 87 4
HIPK2 92 4
HIPK3 113 1
PAK4 106 6
PAK5 101 7
PAK6 105 1
MST2 69 2
Src 84 5
Lck 78 2
CSK 86 5

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