Kinase Profiling Inhibitor Database

Inhibitor Structure Image Brutto MW Action Reference Reference 2 Patent Commercial Vendor Notes Results
H-1152 (Rho Kinase Inhibitor) C16H21N3O2S • 2HCl 392.3 ROCK Ikenoya M. (2002) J. Neurochem. 81 9 Sasaki Y. (2002) Pharmacol. Ther. 93 225 WO2010010702 Merck (Calbiochem) Download

Results as Barchart

View results as a bar chart
1µM

Results as Table

Screening Concentration: 1µM
Kinase % Activity Remainingsort descending Standard Deviation
ROCK 2 2 0
PRK2 15 4
Aurora B 17 6
Aurora C 19 5
PHK 21 5
RSK1 21 5
AMPK 26 0
PKA 31 0
FGF-R1 34 2
BRSK2 38 7
MSK1 38 5
RSK2 39 7
EPH-A2 48 5
MNK1 49 2
MARK3 49 5
MELK 49 2
NUAK1 50 9
LKB1 50 3
PIM3 54 1
GCK 55 0
Lck 55 0
PDK1 56 5
MST2 59 7
PKC alpha 60 5
CDK2-Cyclin A 68 5
MNK2 68 3
BTK 68 11
PKC zeta 75 0
YES1 76 8
MKK1 77 5
CAMKK beta 78 2
Src 78 2
EPH-B3 79 3
CSK 79 5
PIM2 80 3
SGK1 81 5
CHK2 81 0
MLK1 81 18
TBK1 81 20
IGF-1R 82 8
PAK5 84 1
PKB beta 85 3
CHK1 85 0
MLK3 85 8
PAK4 85 1
S6K1 86 7
SmMLCK 86 3
PKD1 86 4
IRR 87 2
PLK1 87 6
PAK6 89 2
ERK1 89 4
MST4 90 6
IKK beta 91 6
SRPK1 91 5
CK2 91 4
DYRK1A 92 0
NEK2a 92 1
GSK3 beta 92 3
PKB alpha 92 2
PIM1 93 0
TTK 93 9
MAPKAP-K2 93 2
DYRK2 94 6
PRAK 95 1
JNK2 96 6
p38 delta MAPK 96 8
IR 97 7
ERK2 97 3
JNK1 97 1
EF2K 97 0
p38 gamma MAPK 98 3
p38 alpha MAPK 99 2
IRAK4 101 6
JNK3 101 0
NEK7 102 4
MINK1 103 4
p38 beta MAPK 103 2
SYK 104 2
ERK8 104 0
HER4 106 1
MAPKAP-K3 107 1
CK1 delta 107 1
DYRK3 108 9
VEGFR1 108 6
CAMKK alpha 108 1
CAMK1 110 5
HIPK2 111 8
NEK6 112 8
IKK epsilon 113 2
HIPK3 114 1

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