Kinase Profiling Inhibitor Database

Inhibitor Structure Image Brutto MW Action Reference Reference 2 Patent Commercial Vendor Notes Results
H-1152 (Rho Kinase Inhibitor) C16H21N3O2S • 2HCl 392.3 ROCK Ikenoya M. (2002) J. Neurochem. 81 9 Sasaki Y. (2002) Pharmacol. Ther. 93 225 WO2010010702 Merck (Calbiochem) Download

Results as Barchart

View results as a bar chart
1µM

Results as Table

Screening Concentration: 1µM
Kinase % Activity Remaining Standard Deviation
MKK1 77 5
ERK1 89 4
ERK2 97 3
JNK1 97 1
JNK2 96 6
JNK3 101 0
p38 alpha MAPK 99 2
p38 beta MAPK 103 2
p38 gamma MAPK 98 3
p38 delta MAPK 96 8
ERK8 104 0
RSK1 21 5
RSK2 39 7
PDK1 56 5
PKB alpha 92 2
PKB beta 85 3
SGK1 81 5
S6K1 86 7
PKA 31 0
ROCK 2 2 0
PRK2 15 4
PKC alpha 60 5
PKC zeta 75 0
PKD1 86 4
MSK1 38 5
MNK1 49 2
MNK2 68 3
MAPKAP-K2 93 2
MAPKAP-K3 107 1
PRAK 95 1
CAMKK alpha 108 1
CAMKK beta 78 2
CAMK1 110 5
SmMLCK 86 3
PHK 21 5
CHK1 85 0
CHK2 81 0
GSK3 beta 92 3
CDK2-Cyclin A 68 5
PLK1 87 6
Aurora B 17 6
Aurora C 19 5
LKB1 50 3
AMPK 26 0
MARK3 49 5
BRSK2 38 7
MELK 49 2
NUAK1 50 9
CK1 delta 107 1
CK2 91 4
DYRK1A 92 0
DYRK2 94 6
DYRK3 108 9
NEK2a 92 1
NEK6 112 8
NEK7 102 4
IKK beta 91 6
IKK epsilon 113 2
TBK1 81 20
PIM1 93 0
PIM2 80 3
PIM3 54 1
SRPK1 91 5
EF2K 97 0
HIPK2 111 8
HIPK3 114 1
PAK4 85 1
PAK5 84 1
PAK6 89 2
MST2 59 7
MST4 90 6
GCK 55 0
MINK1 103 4
MLK1 81 18
MLK3 85 8
IRAK4 101 6
TTK 93 9
Src 78 2
Lck 55 0
CSK 79 5
YES1 76 8
BTK 68 11
SYK 104 2
EPH-A2 48 5
EPH-B3 79 3
FGF-R1 34 2
HER4 106 1
IGF-1R 82 8
IR 97 7
IRR 87 2
VEGFR1 108 6

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