Kinase Profiling Inhibitor Database

Inhibitor Structure Image Brutto MW Action Reference Reference 2 Patent Commercial Vendor Notes Results
Gleevec (Imatinib) C29H31N7O 493.6 BCR-ABL Druker B. J. (2000) J. Clin. Invest. 105 3-7 WO2006039533 Tocris Download

Results as Barchart

View results as a bar chart
10µM
1µM

Results as Table

Screening Concentration: 10µM
Kinase % Activity Remainingsort descending Standard Deviation
Lck 7 1
EPH-B2 24 3
EPH-B3 24 0
RIPK2 39 2
MELK 40 3
EPH-A2 44 1
HER4 46 4
YES1 49 5
TrkA 52 8
NUAK1 54 5
VEGFR1 56 7
CSK 61 0
PIM3 61 3
CAMKK beta 61 7
IR 62 9
CLK2 62 9
MINK1 63 10
CHK2 67 7
PIM1 68 4
CK2 69 6
SYK 70 8
EPH-A4 70 4
IKK epsilon 70 6
HIPK2 70 6
MLK1 71 0
ERK8 72 4
CDK2-Cyclin A 73 3
IKK beta 74 8
MLK3 74 10
Src 75 6
GSK3 beta 75 0
TAO1 75 1
FGF-R1 76 5
TBK1 77 4
PKB alpha 77 4
MST2 78 2
CK1 delta 79 9
JNK3 79 1
TTK 80 2
IGF-1R 80 1
p38 delta MAPK 81 2
TAK1 81 1
p38 beta MAPK 82 2
EF2K 82 7
GCK 83 2
RSK1 83 8
RSK2 83 14
ERK2 83 4
HIPK1 84 8
JNK2 85 0
JAK2 85 6
MNK2 85 6
LKB1 85 5
SmMLCK 85 10
MSK1 86 5
PKB beta 86 12
ERK1 86 11
PHK 86 12
IRR 87 8
S6K1 87 13
PLK1 88 1
DYRK3 88 6
CAMK1 88 13
PIM2 88 2
IRAK4 88 8
DAPK1 88 10
PAK6 89 11
Aurora B 89 7
EPH-B4 89 4
SGK1 89 0
JNK1 90 7
NEK6 90 0
EPH-B1 90 4
PKD1 91 5
Aurora A 91 6
PAK4 92 12
PKC alpha 92 5
BTK 92 0
MARK1 92 10
DYRK1A 93 5
MAPKAP-K2 93 10
MAPKAP-K3 93 4
ROCK 2 94 9
MKK1 94 11
BRSK1 94 3
PRK2 95 7
PAK5 95 0
MNK1 95 2
AMPK 95 6
PKC zeta 96 6
CHK1 97 7
p38 gamma MAPK 97 4
MARK2 97 7
MKK6 98 9
DYRK2 99 9
MEKK1 99 9
PRAK 99 0
MARK4 100 2
BRSK2 100 1
SRPK1 101 10
ASK1 101 6
PAK2 102 13
MST4 102 3
PDK1 102 5
MKK2 104 5
MARK3 105 6
HIPK3 105 1
PKA 105 2
p38 alpha MAPK 106 2
NEK2a 110 5
Screening Concentration: 1µM
Kinase % Activity Remainingsort descending Standard Deviation
Lck 29 1
IR 48 8
EPH-B3 54 3
IKK epsilon 54 14
MINK1 56 9
VEGFR1 64 7
EF2K 67 5
HER4 67 3
MKK1 68 3
EPH-A2 69 7
GSK3 beta 72 7
ERK2 73 9
IKK beta 74 6
p38 beta MAPK 75 2
JAK2 75 0
MELK 76 4
CK2 76 8
RIPK2 77 11
ERK8 77 8
YES1 77 6
MLK1 77 1
NUAK1 78 4
CLK2 78 4
CSK 79 3
BRSK2 80 3
HIPK1 80 1
IGF-1R 80 1
TAO1 81 3
TTK 81 3
RSK1 81 4
MAPKAP-K3 81 2
PKB alpha 81 2
ERK1 82 6
MST2 82 0
ROCK 2 83 3
CDK2-Cyclin A 83 0
RSK2 83 6
TBK1 83 1
CAMKK beta 83 1
PIM3 83 3
MSK1 84 5
DYRK3 84 0
IRR 84 7
LKB1 84 7
SYK 84 8
PKB beta 84 9
PHK 85 3
PAK4 85 4
p38 delta MAPK 85 5
TrkA 85 1
MKK6 85 2
SGK1 85 3
S6K1 86 1
CHK1 86 3
PKC alpha 86 3
HIPK3 86 7
JNK2 87 7
CK1 delta 87 8
PKC zeta 87 9
DYRK2 87 9
MST4 87 2
Aurora B 88 8
NEK6 88 0
BTK 88 5
MARK3 88 1
SmMLCK 88 3
ASK1 89 7
HIPK2 89 15
FGF-R1 89 6
MARK2 89 3
DAPK1 90 2
PDK1 90 2
EPH-B2 91 8
PRK2 91 2
PLK1 91 1
GCK 91 2
CAMK1 91 13
Src 92 8
SRPK1 93 0
p38 gamma MAPK 93 9
AMPK 93 5
MARK1 93 7
EPH-B1 94 1
PAK2 94 5
PAK6 94 0
PRAK 94 2
IRAK4 95 10
PKD1 95 1
PAK5 95 7
TAK1 96 5
JNK3 96 7
PIM1 96 1
PKA 97 2
EPH-B4 97 6
p38 alpha MAPK 98 14
NEK2a 98 11
MAPKAP-K2 98 9
MARK4 98 14
BRSK1 98 12
CHK2 99 7
MNK1 99 2
JNK1 100 6
MLK3 101 5
MKK2 101 11
PIM2 101 9
EPH-A4 101 14
DYRK1A 103 1
MNK2 107 8
MEKK1 110 1
Aurora A 111 10

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