Kinase Profiling Inhibitor Database

Inhibitor Structure Image Brutto MW Action Reference Reference 2 Patent Commercial Vendor Notes Results
EGCG (Epigallocatechin Gallate) C22H18O11 458.4 PKC Dell'Aica I. (2004) EMBO Rep. 5 418-422 Tachibana H. (2004) Nat. Struct. Mol. Biol. 11 380 WO2001051048 Merck (Calbiochem) Download

Results as Barchart

View results as a bar chart
10µM

Results as Table

Screening Concentration: 10µM
Kinase % Activity Remaining Standard Deviation
MKK1 58 24
ERK1 17 1
ERK2 72 4
JNK1 106 8
JNK2 84 2
p38 alpha MAPK 80 8
p38 beta MAPK 96 20
p38 gamma MAPK 98 15
p38 delta MAPK 102 17
ERK8 20 0
RSK1 46 2
RSK2 6 6
PDK1 73 0
PKB alpha 75 20
PKB beta 1 0
SGK1 58 2
S6K1 37 1
PKA 87 1
ROCK 2 74 5
PRK2 82 3
PKC alpha 81 3
PKC zeta 2 1
PKD1 16 1
MSK1 40 4
MNK1 71 10
MNK2 73 7
MAPKAP-K2 22 1
PRAK 5 2
CAMKK beta 65 2
CAMK1 19 8
SmMLCK 51 2
PHK 75 6
CHK1 72 3
CHK2 61 1
GSK3 beta 70 6
CDK2-Cyclin A 88 4
PLK1 7 2
Aurora B 12 3
AMPK 66 2
MARK3 6 1
BRSK2 23 1
MELK 53 1
CK1 delta 90 9
CK2 89 17
DYRK1A 6 0
DYRK2 0 1
DYRK3 5 0
NEK2a 5 1
NEK6 56 4
IKK beta 21 3
IKK epsilon 27 4
TBK1 65 4
PIM1 15 2
PIM2 47 0
PIM3 17 0
SRPK1 5 3
EF2K 86 2
HIPK2 15 0
PAK4 22 1
PAK5 35 1
PAK6 8 4
MST2 37 0
MST4 24 1
Src 21 0
Lck 90 3
CSK 88 10
YES1 12 3
BTK 18 0
SYK 67 8
EPH-A2 76 0
EPH-B3 1 0
FGF-R1 6 0
IGF-1R 19 4
IR 70 5
IRR 28 1
VEGFR1 20 1

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