Kinase Profiling Inhibitor Database

Inhibitor Structure Image Brutto MW Action Reference Reference 2 Patent Commercial Vendor Notes Results
D 4476 C23H18N4O3 398.41 CK1 Liverton N.J. (1999) J. Med. Chem 42 2180-2190 WO2008066626 Merck (Calbiochem) Download

Results as Barchart

View results as a bar chart
10µM

Results as Table

Screening Concentration: 10µM
Kinase % Activity Remaining Standard Deviation
MKK1 93 2
ERK1 101 3
ERK2 85 1
JNK1 86 4
JNK2 76 6
JNK3 81 0
p38 alpha MAPK 38 1
p38 beta MAPK 55 2
p38 gamma MAPK 87 0
p38 delta MAPK 88 2
ERK8 79 4
RSK1 81 1
RSK2 81 1
PDK1 84 1
PKB alpha 106 8
PKB beta 88 1
SGK1 73 1
S6K1 76 5
PKA 85 5
ROCK 2 104 1
PRK2 107 4
PKC alpha 94 5
PKC zeta 81 0
PKD1 43 4
MSK1 90 7
MNK1 81 1
MNK2 88 4
MAPKAP-K2 99 4
MAPKAP-K3 98 2
PRAK 77 2
CAMKK alpha 89 1
CAMKK beta 100 2
CAMK1 88 2
SmMLCK 80 5
PHK 88 3
CHK1 83 8
CHK2 92 5
GSK3 beta 88 5
CDK2-Cyclin A 112 8
PLK1 91 1
Aurora B 75 5
Aurora C 81 4
AMPK 98 0
MARK3 82 4
BRSK2 89 5
MELK 83 1
CK1 delta 3 0
CK2 82 5
DYRK1A 86 6
DYRK2 93 3
DYRK3 76 1
NEK2a 89 6
NEK6 78 1
NEK7 99 6
IKK beta 63 3
IKK epsilon 88 4
TBK1 95 9
PIM1 93 7
PIM2 90 4
PIM3 82 4
SRPK1 84 5
EF2K 100 1
HIPK2 80 4
HIPK3 96 2
PAK4 105 1
PAK5 100 1
PAK6 103 4
MST2 96 2
MST4 83 0
Src 82 0
Lck 82 5
CSK 81 5
YES1 81 2
BTK 71 5
SYK 82 2
EPH-A2 97 12
EPH-B3 115 8
FGF-R1 69 2
IGF-1R 77 0
IR 108 9
IRR 55 1
VEGFR1 85 12

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