Kinase Profiling Inhibitor Database

Inhibitor Structure Image Brutto MW Action Reference Reference 2 Patent Commercial Vendor Notes Results
CKI-7 C11H12ClN3O2S • 2HCl 358.67 CK1 Rena G. (2004) EMBO Rep. 5 60-65 WO2002102768 Sigma Download

Results as Barchart

View results as a bar chart
2.5µM
25µM

Results as Table

Screening Concentration: 25µM
Kinase % Activity Remainingsort descending Standard Deviation
CK1 delta 12 0
SGK1 25 2
MNK1 26 0
PIM1 28 1
PIM3 28 0
ERK8 29 6
AMPK 29 5
DYRK1A 39 6
MSK1 42 2
BRSK2 42 1
DYRK3 46 1
PRK2 47 3
RSK1 48 3
S6K1 49 5
PKC zeta 52 0
PKB alpha 54 1
PIM2 55 6
IRR 60 4
PKD1 60 3
CDK2-Cyclin A 62 4
RSK2 63 4
MELK 63 4
CHK2 64 0
CK2 65 1
PKA 65 6
ROCK 2 65 8
IKK epsilon 70 4
EPH-A2 71 0
PHK 72 5
GSK3 beta 75 4
SYK 76 11
MNK2 76 0
MKK1 76 2
DYRK2 76 2
Aurora B 78 0
MARK3 78 5
PAK6 78 3
p38 delta MAPK 79 8
CSK 79 5
PLK1 81 4
PRAK 81 4
CAMK1 82 3
FGF-R1 83 7
PDK1 83 3
Lck 83 6
SmMLCK 84 7
MAPKAP-K2 85 3
NEK2a 85 4
PKC alpha 86 2
SRPK1 86 2
MAPKAP-K3 86 7
CAMKK alpha 86 4
HIPK3 86 7
CAMKK beta 86 3
PAK5 86 7
CHK1 86 2
JNK2 86 9
IKK beta 87 2
TBK1 87 9
PAK4 88 3
PKB beta 89 4
NEK6 90 2
MST2 91 0
JNK1 91 0
Src 92 1
EF2K 94 6
MST4 95 3
Aurora C 95 3
HIPK2 98 7
ERK2 100 2
p38 beta MAPK 101 9
p38 gamma MAPK 101 3
ERK1 101 3
JNK3 102 0
NEK7 102 3
p38 alpha MAPK 103 4
YES1 110 12
Screening Concentration: 2.5µM
Kinase % Activity Remainingsort descending Standard Deviation
CK1 delta 62 3
PIM2 72 1
MKK1 72 12
PRK2 73 10
S6K1 76 0
MNK1 76 8
AMPK 78 1
CHK2 79 9
MST4 80 3
Lck 81 4
IKK beta 82 5
GSK3 beta 82 5
JNK1 82 8
PKC alpha 82 2
JNK2 83 3
JNK3 84 12
DYRK1A 84 0
SGK1 85 10
CHK1 87 5
p38 alpha MAPK 87 6
MAPKAP-K2 88 3
Src 89 2
CSK 89 16
p38 gamma MAPK 89 3
Aurora B 90 1
NEK2a 91 0
PRAK 91 1
CAMK1 91 7
ROCK 2 92 11
PKD1 92 1
RSK1 93 2
MNK2 93 0
MAPKAP-K3 94 6
NEK6 94 4
p38 beta MAPK 94 5
PDK1 95 11
ERK8 95 4
PKB beta 96 3
PKB alpha 97 2
CDK2-Cyclin A 98 14
MARK3 98 7
SRPK1 99 6
PKA 99 6
NEK7 100 7
CK2 100 4
ERK2 101 6
RSK2 103 3
PHK 103 2
PLK1 105 13
MSK1 110 36
EF2K 111 4
SmMLCK 122 13

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