Kinase Profiling Inhibitor Database

Inhibitor Structure Image Brutto MW Action Reference Reference 2 Patent Commercial Vendor Notes Results
CKI-7 C11H12ClN3O2S • 2HCl 358.67 CK1 Rena G. (2004) EMBO Rep. 5 60-65 WO2002102768 Sigma Download

Results as Barchart

View results as a bar chart
2.5µM
25µM

Results as Table

Screening Concentration: 2.5µM
Kinase % Activity Remaining Standard Deviation
MKK1 72 12
ERK2 101 6
JNK1 82 8
JNK2 83 3
JNK3 84 12
p38 alpha MAPK 87 6
p38 beta MAPK 94 5
p38 gamma MAPK 89 3
ERK8 95 4
RSK1 93 2
RSK2 103 3
PDK1 95 11
PKB alpha 97 2
PKB beta 96 3
SGK1 85 10
S6K1 76 0
PKA 99 6
ROCK 2 92 11
PRK2 73 10
PKC alpha 82 2
PKD1 92 1
MSK1 110 36
MNK1 76 8
MNK2 93 0
MAPKAP-K2 88 3
MAPKAP-K3 94 6
PRAK 91 1
CAMK1 91 7
SmMLCK 122 13
PHK 103 2
CHK1 87 5
CHK2 79 9
GSK3 beta 82 5
CDK2-Cyclin A 98 14
PLK1 105 13
Aurora B 90 1
AMPK 78 1
MARK3 98 7
CK1 delta 62 3
CK2 100 4
DYRK1A 84 0
NEK2a 91 0
NEK6 94 4
NEK7 100 7
IKK beta 82 5
PIM2 72 1
SRPK1 99 6
EF2K 111 4
MST4 80 3
Src 89 2
Lck 81 4
CSK 89 16
Screening Concentration: 25µM
Kinase % Activity Remaining Standard Deviation
MKK1 76 2
ERK1 101 3
ERK2 100 2
JNK1 91 0
JNK2 86 9
JNK3 102 0
p38 alpha MAPK 103 4
p38 beta MAPK 101 9
p38 gamma MAPK 101 3
p38 delta MAPK 79 8
ERK8 29 6
RSK1 48 3
RSK2 63 4
PDK1 83 3
PKB alpha 54 1
PKB beta 89 4
SGK1 25 2
S6K1 49 5
PKA 65 6
ROCK 2 65 8
PRK2 47 3
PKC alpha 86 2
PKC zeta 52 0
PKD1 60 3
MSK1 42 2
MNK1 26 0
MNK2 76 0
MAPKAP-K2 85 3
MAPKAP-K3 86 7
PRAK 81 4
CAMKK alpha 86 4
CAMKK beta 86 3
CAMK1 82 3
SmMLCK 84 7
PHK 72 5
CHK1 86 2
CHK2 64 0
GSK3 beta 75 4
CDK2-Cyclin A 62 4
PLK1 81 4
Aurora B 78 0
Aurora C 95 3
AMPK 29 5
MARK3 78 5
BRSK2 42 1
MELK 63 4
CK1 delta 12 0
CK2 65 1
DYRK1A 39 6
DYRK2 76 2
DYRK3 46 1
NEK2a 85 4
NEK6 90 2
NEK7 102 3
IKK beta 87 2
IKK epsilon 70 4
TBK1 87 9
PIM1 28 1
PIM2 55 6
PIM3 28 0
SRPK1 86 2
EF2K 94 6
HIPK2 98 7
HIPK3 86 7
PAK4 88 3
PAK5 86 7
PAK6 78 3
MST2 91 0
MST4 95 3
Src 92 1
Lck 83 6
CSK 79 5
YES1 110 12
SYK 76 11
EPH-A2 71 0
FGF-R1 83 7
IRR 60 4

Do you need any help? Please get in touch and we’ll be happy to lend a hand.