Kinase Profiling Inhibitor Database

Inhibitor Structure Image Brutto MW Action Reference Reference 2 Patent Commercial Vendor Notes Results
CGP-57380 analog (SHN-095) C13H14N6 254.29 MNK Download

Results as Barchart

View results as a bar chart
1µM
10µM

Results as Table

Screening Concentration: 1µM
Kinase % Activity Remainingsort descending Standard Deviation
NEK6 73 5
ERK8 76 8
CK1 delta 77 12
CHK2 84 4
PAK4 86 1
RSK2 88 2
NEK7 88 1
MARK3 89 0
PKC zeta 89 2
MST2 90 3
DYRK1A 90 1
MAPKAP-K3 91 3
MNK1 92 5
Aurora C 92 0
CAMK1 92 6
MSK1 92 13
CK2 93 0
SmMLCK 93 4
DYRK2 93 2
PKB beta 95 0
PLK1 96 0
Aurora B 96 3
EF2K 97 5
Src 97 0
CSK 97 4
CDK2-Cyclin A 97 2
JNK1 99 6
PKB alpha 100 1
p38 delta MAPK 101 10
MAPKAP-K2 101 0
PRAK 101 8
JNK3 101 5
IKK beta 101 3
BRSK2 102 6
PKC alpha 102 13
MNK2 103 1
PDK1 103 3
PAK6 103 2
SGK1 104 2
JNK2 104 3
PKA 106 1
PHK 106 8
SRPK1 107 1
NEK2a 107 13
RSK1 108 2
MELK 108 4
CHK1 109 8
AMPK 111 3
CAMKK alpha 111 2
ERK1 114 2
GSK3 beta 114 3
PKD1 114 1
PIM2 115 6
ERK2 116 3
ROCK 2 117 3
p38 alpha MAPK 118 2
PRK2 119 1
PIM3 120 2
p38 gamma MAPK 120 5
HIPK2 124 0
CAMKK beta 125 2
Lck 125 4
S6K1 127 2
PIM1 127 1
p38 beta MAPK 131 2
HIPK3 136 1
DYRK3 136 3
PAK5 139 8
MKK1 187 3
Screening Concentration: 10µM
Kinase % Activity Remainingsort descending Standard Deviation
MNK2 76 3
NEK6 81 1
CSK 85 7
Aurora B 87 4
CK1 delta 87 4
SmMLCK 87 2
CAMK1 89 5
DYRK2 89 1
NEK7 91 1
CDK2-Cyclin A 91 3
ERK8 93 6
CK2 93 2
MARK3 94 6
PAK4 95 5
MNK1 96 1
EF2K 96 2
JNK1 97 2
CHK2 98 9
SRPK1 98 7
PKA 98 11
RSK2 99 4
MSK1 100 1
BRSK2 100 8
PKB beta 100 8
Src 100 0
IKK beta 101 2
RSK1 101 1
DYRK1A 101 10
PHK 101 1
JNK3 102 11
MST2 102 3
PAK6 102 9
MAPKAP-K2 104 0
p38 delta MAPK 105 4
PDK1 105 5
PLK1 106 8
ROCK 2 106 0
ERK1 108 1
PRAK 109 5
PRK2 110 6
p38 beta MAPK 111 3
ERK2 111 0
PKC zeta 112 1
PIM2 113 2
SGK1 113 1
AMPK 114 2
PKB alpha 114 3
CAMKK alpha 114 1
PIM1 115 11
CHK1 115 3
NEK2a 115 2
JNK2 117 7
PKC alpha 117 1
Aurora C 117 4
CAMKK beta 117 4
MELK 118 3
PIM3 121 3
p38 alpha MAPK 122 11
PAK5 124 1
PKD1 125 0
HIPK2 125 3
MAPKAP-K3 130 1
Lck 131 2
p38 gamma MAPK 132 4
GSK3 beta 133 7
S6K1 137 2
DYRK3 137 9
HIPK3 138 4
MKK1 191 3

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