Kinase Profiling Inhibitor Database

Inhibitor Structure Image Brutto MW Action Reference Reference 2 Patent Commercial Vendor Notes Results
CGP-57380 analog (SHN-095) C13H14N6 254.29 MNK Download

Results as Barchart

View results as a bar chart
1µM
10µM

Results as Table

Screening Concentration: 1µM
Kinase % Activity Remaining Standard Deviation
MKK1 187 3
ERK1 114 2
ERK2 116 3
JNK1 99 6
JNK2 104 3
JNK3 101 5
p38 alpha MAPK 118 2
p38 beta MAPK 131 2
p38 gamma MAPK 120 5
p38 delta MAPK 101 10
ERK8 76 8
RSK1 108 2
RSK2 88 2
PDK1 103 3
PKB alpha 100 1
PKB beta 95 0
SGK1 104 2
S6K1 127 2
PKA 106 1
ROCK 2 117 3
PRK2 119 1
PKC alpha 102 13
PKC zeta 89 2
PKD1 114 1
MSK1 92 13
MNK1 92 5
MNK2 103 1
MAPKAP-K2 101 0
MAPKAP-K3 91 3
PRAK 101 8
CAMKK alpha 111 2
CAMKK beta 125 2
CAMK1 92 6
SmMLCK 93 4
PHK 106 8
CHK1 109 8
CHK2 84 4
GSK3 beta 114 3
CDK2-Cyclin A 97 2
PLK1 96 0
Aurora B 96 3
Aurora C 92 0
AMPK 111 3
MARK3 89 0
BRSK2 102 6
MELK 108 4
CK1 delta 77 12
CK2 93 0
DYRK1A 90 1
DYRK2 93 2
DYRK3 136 3
NEK2a 107 13
NEK6 73 5
NEK7 88 1
IKK beta 101 3
PIM1 127 1
PIM2 115 6
PIM3 120 2
SRPK1 107 1
EF2K 97 5
HIPK2 124 0
HIPK3 136 1
PAK4 86 1
PAK5 139 8
PAK6 103 2
MST2 90 3
Src 97 0
Lck 125 4
CSK 97 4
Screening Concentration: 10µM
Kinase % Activity Remaining Standard Deviation
MKK1 191 3
ERK1 108 1
ERK2 111 0
JNK1 97 2
JNK2 117 7
JNK3 102 11
p38 alpha MAPK 122 11
p38 beta MAPK 111 3
p38 gamma MAPK 132 4
p38 delta MAPK 105 4
ERK8 93 6
RSK1 101 1
RSK2 99 4
PDK1 105 5
PKB alpha 114 3
PKB beta 100 8
SGK1 113 1
S6K1 137 2
PKA 98 11
ROCK 2 106 0
PRK2 110 6
PKC alpha 117 1
PKC zeta 112 1
PKD1 125 0
MSK1 100 1
MNK1 96 1
MNK2 76 3
MAPKAP-K2 104 0
MAPKAP-K3 130 1
PRAK 109 5
CAMKK alpha 114 1
CAMKK beta 117 4
CAMK1 89 5
SmMLCK 87 2
PHK 101 1
CHK1 115 3
CHK2 98 9
GSK3 beta 133 7
CDK2-Cyclin A 91 3
PLK1 106 8
Aurora B 87 4
Aurora C 117 4
AMPK 114 2
MARK3 94 6
BRSK2 100 8
MELK 118 3
CK1 delta 87 4
CK2 93 2
DYRK1A 101 10
DYRK2 89 1
DYRK3 137 9
NEK2a 115 2
NEK6 81 1
NEK7 91 1
IKK beta 101 2
PIM1 115 11
PIM2 113 2
PIM3 121 3
SRPK1 98 7
EF2K 96 2
HIPK2 125 3
HIPK3 138 4
PAK4 95 5
PAK5 124 1
PAK6 102 9
MST2 102 3
Src 100 0
Lck 131 2
CSK 85 7

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