Kinase Profiling Inhibitor Database

Inhibitor Structure Image Brutto MW Action Reference Reference 2 Patent Commercial Vendor Notes Results
CGP-57380 analog (SHN-093) C12H11FN6 258.25 MNK Proud C.G. (2005) Immunity 23 177-189 Download

Results as Barchart

View results as a bar chart
1µM
10µM

Results as Table

Screening Concentration: 1µM
Kinase % Activity Remaining Standard Deviation
MKK1 108 6
ERK1 124 6
ERK2 107 2
JNK1 112 1
JNK2 122 5
JNK3 104 2
p38 alpha MAPK 93 5
p38 beta MAPK 132 5
p38 gamma MAPK 113 3
p38 delta MAPK 104 4
ERK8 76 8
RSK1 121 4
RSK2 110 5
PDK1 92 5
PKB alpha 124 4
PKB beta 103 3
SGK1 97 5
S6K1 114 0
PKA 106 1
ROCK 2 117 2
PRK2 103 8
PKC alpha 120 2
PKC zeta 97 4
PKD1 107 3
MSK1 97 1
MNK1 95 6
MNK2 104 1
MAPKAP-K2 97 0
MAPKAP-K3 137 1
PRAK 107 2
CAMKK alpha 89 3
CAMKK beta 112 10
CAMK1 103 1
SmMLCK 94 9
PHK 113 9
CHK1 118 6
CHK2 103 1
GSK3 beta 119 10
CDK2-Cyclin A 98 3
PLK1 92 0
Aurora B 98 1
Aurora C 125 2
AMPK 105 1
MARK3 82 3
BRSK2 99 9
MELK 109 2
CK1 delta 97 0
CK2 91 11
DYRK1A 105 2
DYRK2 86 7
DYRK3 119 1
NEK2a 102 1
NEK6 95 1
NEK7 94 8
IKK beta 98 2
PIM1 111 6
PIM2 100 2
PIM3 101 2
SRPK1 137 2
EF2K 102 1
HIPK2 113 0
HIPK3 143 1
PAK4 86 1
PAK5 109 4
PAK6 113 5
MST2 102 6
Src 96 11
Lck 112 2
CSK 88 12
Screening Concentration: 10µM
Kinase % Activity Remaining Standard Deviation
MKK1 104 2
ERK1 111 5
ERK2 110 0
JNK1 102 7
JNK2 124 5
JNK3 104 1
p38 alpha MAPK 80 5
p38 beta MAPK 127 4
p38 gamma MAPK 112 1
p38 delta MAPK 109 1
ERK8 70 3
RSK1 102 5
RSK2 107 6
PDK1 106 5
PKB alpha 106 3
PKB beta 103 1
SGK1 98 3
S6K1 114 4
PKA 107 2
ROCK 2 113 7
PRK2 109 1
PKC alpha 121 3
PKC zeta 102 2
PKD1 107 3
MSK1 84 2
MNK1 92 0
MNK2 103 7
MAPKAP-K2 95 3
MAPKAP-K3 132 1
PRAK 109 0
CAMKK alpha 112 1
CAMKK beta 120 6
CAMK1 97 2
SmMLCK 107 3
PHK 119 1
CHK1 112 4
CHK2 96 4
GSK3 beta 125 1
CDK2-Cyclin A 96 1
PLK1 94 3
Aurora B 82 7
Aurora C 117 2
AMPK 107 2
MARK3 79 4
BRSK2 92 2
MELK 91 1
CK1 delta 62 6
CK2 96 9
DYRK1A 101 2
DYRK2 83 4
DYRK3 101 0
NEK2a 100 8
NEK6 95 1
NEK7 99 5
IKK beta 96 3
PIM1 115 7
PIM2 109 9
PIM3 95 2
SRPK1 129 2
EF2K 103 8
HIPK2 105 0
HIPK3 136 8
PAK4 97 1
PAK5 125 4
PAK6 101 2
MST2 104 4
Src 63 5
Lck 81 5
CSK 76 8

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