Kinase Profiling Inhibitor Database

Inhibitor Structure Image Brutto MW Action Reference Reference 2 Patent Commercial Vendor Notes Results
CGP-57380 C11H9FN6 244.23 MNK Knauf U. (2001) Mol. Cell. Biol. 21 5500-5511 Proud C.G. (2005) Immunity 23 177-189 WO2010055072 Tocris Download

Results as Barchart

View results as a bar chart
1µM
10µM

Results as Table

Screening Concentration: 1µM
Kinase % Activity Remainingsort ascending Standard Deviation
SYK 131 3
MAPKAP-K2 118 2
IKK epsilon 106 3
HIPK3 106 0
MAPKAP-K3 104 4
TBK1 104 1
NEK7 103 7
CAMKK alpha 102 2
JNK1 102 7
p38 beta MAPK 102 1
p38 gamma MAPK 102 5
p38 delta MAPK 101 5
AMPK 101 8
SmMLCK 99 1
SRPK1 98 6
S6K1 98 4
ROCK 2 97 5
JNK2 97 4
PRAK 96 4
PKB alpha 96 4
JNK3 96 0
CAMK1 95 1
CHK2 95 2
HIPK2 94 1
NEK6 93 1
DYRK1A 91 6
NEK2a 91 2
PLK1 91 2
EF2K 90 2
PKB beta 90 5
CAMKK beta 90 5
PRK2 90 5
PKC alpha 90 6
PIM2 90 1
PKC zeta 88 5
CK2 87 3
PAK5 87 1
GSK3 beta 87 6
ERK8 86 6
PKD1 86 4
IKK beta 85 3
EPH-A2 85 1
MSK1 85 4
CHK1 84 6
RSK2 83 1
PIM1 83 5
Aurora C 82 4
ERK2 82 3
p38 alpha MAPK 82 6
CDK2-Cyclin A 81 1
MARK3 80 1
PAK6 79 5
MST4 79 9
ERK1 78 4
DYRK2 77 3
PAK4 76 4
IRR 75 10
PDK1 74 3
FGF-R1 73 1
MST2 72 6
PKA 71 5
Lck 70 6
MELK 68 6
DYRK3 67 5
Src 67 6
CSK 67 1
Aurora B 64 4
PHK 61 3
YES1 59 5
SGK1 57 2
MNK2 56 2
MKK1 56 1
PIM3 54 2
RSK1 51 2
BRSK2 39 8
MNK1 35 2
CK1 delta 30 3
Screening Concentration: 10µM
Kinase % Activity Remainingsort ascending Standard Deviation
NEK6 127 5
MAPKAP-K3 125 12
JNK2 121 4
PKB alpha 116 4
JNK3 116 14
p38 delta MAPK 111 10
JNK1 108 4
PAK6 106 3
PRAK 103 7
EF2K 103 10
NEK7 100 5
MAPKAP-K2 100 6
PKC zeta 96 5
MSK1 93 0
IKK epsilon 93 6
HIPK3 91 5
PKB beta 85 3
SmMLCK 85 13
HIPK2 83 0
p38 beta MAPK 83 7
PIM2 83 7
CSK 82 8
p38 gamma MAPK 82 12
SYK 81 4
PAK5 79 5
PKA 76 4
ROCK 2 76 9
PRK2 76 4
PKD1 75 3
SRPK1 75 4
PAK4 74 9
PKC alpha 72 9
PLK1 71 13
ERK2 70 13
GSK3 beta 68 4
TBK1 68 3
IKK beta 66 0
CAMKK beta 64 2
AMPK 64 6
DYRK1A 62 10
NEK2a 62 0
MELK 61 3
S6K1 59 8
CK2 55 7
CAMK1 55 2
p38 alpha MAPK 54 0
MST4 51 2
MARK3 48 11
Aurora C 47 5
RSK2 46 9
MST2 46 1
SGK1 41 2
RSK1 41 1
CHK2 39 0
IRR 38 6
DYRK3 36 8
PDK1 34 7
PIM1 31 6
FGF-R1 30 0
DYRK2 29 0
PHK 27 3
Src 25 4
EPH-A2 25 1
MNK2 24 11
ERK1 21 2
CHK1 21 1
CDK2-Cyclin A 21 1
ERK8 16 1
YES1 15 4
Lck 14 0
PIM3 14 0
MKK1 12 0
Aurora B 11 0
BRSK2 10 0
MNK1 6 1
CK1 delta 4 0

Do you need any help? Please get in touch and we’ll be happy to lend a hand.