Kinase Profiling Inhibitor Database

Inhibitor Structure Image Brutto MW Action Reference Reference 2 Patent Commercial Vendor Notes Results
CGP-57380 C11H9FN6 244.23 MNK Knauf U. (2001) Mol. Cell. Biol. 21 5500-5511 Proud C.G. (2005) Immunity 23 177-189 WO2010055072 Tocris Download

Results as Barchart

View results as a bar chart
1µM
10µM

Results as Table

Screening Concentration: 10µM
Kinase % Activity Remaining Standard Deviation
MKK1 12 0
ERK1 21 2
ERK2 70 13
JNK1 108 4
JNK2 121 4
JNK3 116 14
p38 alpha MAPK 54 0
p38 beta MAPK 83 7
p38 gamma MAPK 82 12
p38 delta MAPK 111 10
ERK8 16 1
RSK1 41 1
RSK2 46 9
PDK1 34 7
PKB alpha 116 4
PKB beta 85 3
SGK1 41 2
S6K1 59 8
PKA 76 4
ROCK 2 76 9
PRK2 76 4
PKC alpha 72 9
PKC zeta 96 5
PKD1 75 3
MSK1 93 0
MNK1 6 1
MNK2 24 11
MAPKAP-K2 100 6
MAPKAP-K3 125 12
PRAK 103 7
CAMKK beta 64 2
CAMK1 55 2
SmMLCK 85 13
PHK 27 3
CHK1 21 1
CHK2 39 0
GSK3 beta 68 4
CDK2-Cyclin A 21 1
PLK1 71 13
Aurora B 11 0
Aurora C 47 5
AMPK 64 6
MARK3 48 11
BRSK2 10 0
MELK 61 3
CK1 delta 4 0
CK2 55 7
DYRK1A 62 10
DYRK2 29 0
DYRK3 36 8
NEK2a 62 0
NEK6 127 5
NEK7 100 5
IKK beta 66 0
IKK epsilon 93 6
TBK1 68 3
PIM1 31 6
PIM2 83 7
PIM3 14 0
SRPK1 75 4
EF2K 103 10
HIPK2 83 0
HIPK3 91 5
PAK4 74 9
PAK5 79 5
PAK6 106 3
MST2 46 1
MST4 51 2
Src 25 4
Lck 14 0
CSK 82 8
YES1 15 4
SYK 81 4
EPH-A2 25 1
FGF-R1 30 0
IRR 38 6
Screening Concentration: 1µM
Kinase % Activity Remaining Standard Deviation
MKK1 56 1
ERK1 78 4
ERK2 82 3
JNK1 102 7
JNK2 97 4
JNK3 96 0
p38 alpha MAPK 82 6
p38 beta MAPK 102 1
p38 gamma MAPK 102 5
p38 delta MAPK 101 5
ERK8 86 6
RSK1 51 2
RSK2 83 1
PDK1 74 3
PKB alpha 96 4
PKB beta 90 5
SGK1 57 2
S6K1 98 4
PKA 71 5
ROCK 2 97 5
PRK2 90 5
PKC alpha 90 6
PKC zeta 88 5
PKD1 86 4
MSK1 85 4
MNK1 35 2
MNK2 56 2
MAPKAP-K2 118 2
MAPKAP-K3 104 4
PRAK 96 4
CAMKK alpha 102 2
CAMKK beta 90 5
CAMK1 95 1
SmMLCK 99 1
PHK 61 3
CHK1 84 6
CHK2 95 2
GSK3 beta 87 6
CDK2-Cyclin A 81 1
PLK1 91 2
Aurora B 64 4
Aurora C 82 4
AMPK 101 8
MARK3 80 1
BRSK2 39 8
MELK 68 6
CK1 delta 30 3
CK2 87 3
DYRK1A 91 6
DYRK2 77 3
DYRK3 67 5
NEK2a 91 2
NEK6 93 1
NEK7 103 7
IKK beta 85 3
IKK epsilon 106 3
TBK1 104 1
PIM1 83 5
PIM2 90 1
PIM3 54 2
SRPK1 98 6
EF2K 90 2
HIPK2 94 1
HIPK3 106 0
PAK4 76 4
PAK5 87 1
PAK6 79 5
MST2 72 6
MST4 79 9
Src 67 6
Lck 70 6
CSK 67 1
YES1 59 5
SYK 131 3
EPH-A2 85 1
FGF-R1 73 1
IRR 75 10

Do you need any help? Please get in touch and we’ll be happy to lend a hand.