Kinase Profiling Inhibitor Database

Inhibitor Structure Image Brutto MW Action Reference Reference 2 Patent Commercial Vendor Notes Results
BX-320 C23H31BrN8O3 547.45 PDK1 Feldman R.I. (2005) Journal of Biological Chemistry 280 19867-19874 WO2004048343 SuperNova Life Science Download

Results as Barchart

View results as a bar chart
1µM
10µM

Results as Table

Screening Concentration: 1µM
Kinase % Activity Remainingsort ascending Standard Deviation
NEK6 117 14
NEK7 116 14
EF2K 110 7
SYK 109 11
p38 alpha MAPK 107 6
JNK1 106 8
MAPKAP-K3 106 4
CK2 105 10
PIM2 104 9
PKB beta 104 0
SmMLCK 103 4
MST4 102 3
MAPKAP-K2 102 7
HIPK3 101 6
PHK 101 1
YES1 100 2
S6K1 100 7
CHK2 99 2
PKA 99 1
PKC alpha 98 1
JNK3 97 5
PIM3 97 2
MST2 97 3
PLK1 96 7
HIPK2 96 8
JNK2 95 4
IKK beta 95 9
NEK2a 94 3
CSK 93 14
p38 delta MAPK 93 2
PAK5 93 1
DYRK2 92 0
MSK1 91 0
CDK2-Cyclin A 90 6
RSK1 89 3
CAMKK alpha 89 13
CK1 delta 89 6
IRR 88 1
MNK1 88 13
RSK2 88 2
PAK6 88 2
PIM1 86 1
p38 gamma MAPK 86 3
DYRK1A 86 3
DYRK3 86 9
PKD1 85 15
ERK2 84 0
Src 84 0
PKC zeta 82 5
PRAK 82 14
PKB alpha 82 14
EPH-A2 81 5
ERK1 81 8
SRPK1 79 8
PAK4 78 7
ROCK 2 77 4
Lck 76 4
SGK1 75 5
p38 beta MAPK 72 7
BRSK2 72 3
CHK1 71 4
PRK2 71 1
MNK2 71 5
CAMK1 71 4
CAMKK beta 62 9
MKK1 60 6
ERK8 57 10
MELK 56 10
GSK3 beta 55 1
AMPK 46 3
FGF-R1 44 3
IKK epsilon 37 4
MARK3 35 3
PDK1 33 0
TBK1 31 1
Aurora C 8 0
Aurora B 6 2
Screening Concentration: 10µM
Kinase % Activity Remainingsort ascending Standard Deviation
JNK3 102 3
MST4 100 2
HIPK3 100 5
CK1 delta 96 6
p38 alpha MAPK 95 7
CK2 95 6
SmMLCK 94 4
NEK6 91 1
NEK7 84 11
EF2K 83 4
PKC zeta 79 8
p38 gamma MAPK 79 0
PKB beta 79 0
JNK1 78 3
MSK1 76 8
MAPKAP-K3 76 5
PHK 76 3
p38 delta MAPK 74 9
MNK1 74 4
HIPK2 74 2
EPH-A2 73 8
ERK2 73 9
ERK1 72 3
PIM2 71 2
MST2 70 5
DYRK2 70 0
IKK beta 69 2
PLK1 69 1
SRPK1 69 2
MAPKAP-K2 68 1
PKC alpha 67 0
PRAK 66 9
CSK 66 10
IRR 65 7
JNK2 65 7
DYRK1A 64 8
PIM1 63 3
SYK 62 3
YES1 62 8
S6K1 61 5
NEK2a 61 4
PAK6 60 0
PKA 58 3
PKB alpha 57 1
ROCK 2 56 5
PIM3 53 4
CAMK1 52 5
CAMKK alpha 47 4
PKD1 46 10
p38 beta MAPK 45 4
SGK1 45 2
CHK2 45 0
DYRK3 44 1
PRK2 42 0
RSK2 41 6
Lck 41 2
PAK5 40 7
Src 40 2
RSK1 39 6
CDK2-Cyclin A 35 0
CHK1 33 0
MNK2 31 1
MKK1 29 1
PAK4 26 0
BRSK2 22 3
GSK3 beta 22 0
CAMKK beta 19 1
ERK8 18 1
AMPK 13 2
FGF-R1 13 1
MELK 11 0
MARK3 7 0
PDK1 7 0
Aurora C 6 0
TBK1 5 0
Aurora B 4 0
IKK epsilon 3 8

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