Kinase Profiling Inhibitor Database

Inhibitor Structure Image Brutto MW Action Reference Reference 2 Patent Commercial Vendor Notes Results
BX-320 C23H31BrN8O3 547.45 PDK1 Feldman R.I. (2005) Journal of Biological Chemistry 280 19867-19874 WO2004048343 SuperNova Life Science Download

Results as Barchart

View results as a bar chart
1µM
10µM

Results as Table

Screening Concentration: 10µM
Kinase % Activity Remaining Standard Deviation
MKK1 29 1
ERK1 72 3
ERK2 73 9
JNK1 78 3
JNK2 65 7
JNK3 102 3
p38 alpha MAPK 95 7
p38 beta MAPK 45 4
p38 gamma MAPK 79 0
p38 delta MAPK 74 9
ERK8 18 1
RSK1 39 6
RSK2 41 6
PDK1 7 0
PKB alpha 57 1
PKB beta 79 0
SGK1 45 2
S6K1 61 5
PKA 58 3
ROCK 2 56 5
PRK2 42 0
PKC alpha 67 0
PKC zeta 79 8
PKD1 46 10
MSK1 76 8
MNK1 74 4
MNK2 31 1
MAPKAP-K2 68 1
MAPKAP-K3 76 5
PRAK 66 9
CAMKK alpha 47 4
CAMKK beta 19 1
CAMK1 52 5
SmMLCK 94 4
PHK 76 3
CHK1 33 0
CHK2 45 0
GSK3 beta 22 0
CDK2-Cyclin A 35 0
PLK1 69 1
Aurora B 4 0
Aurora C 6 0
AMPK 13 2
MARK3 7 0
BRSK2 22 3
MELK 11 0
CK1 delta 96 6
CK2 95 6
DYRK1A 64 8
DYRK2 70 0
DYRK3 44 1
NEK2a 61 4
NEK6 91 1
NEK7 84 11
IKK beta 69 2
IKK epsilon 3 8
TBK1 5 0
PIM1 63 3
PIM2 71 2
PIM3 53 4
SRPK1 69 2
EF2K 83 4
HIPK2 74 2
HIPK3 100 5
PAK4 26 0
PAK5 40 7
PAK6 60 0
MST2 70 5
MST4 100 2
Src 40 2
Lck 41 2
CSK 66 10
YES1 62 8
SYK 62 3
EPH-A2 73 8
FGF-R1 13 1
IRR 65 7
Screening Concentration: 1µM
Kinase % Activity Remaining Standard Deviation
MKK1 60 6
ERK1 81 8
ERK2 84 0
JNK1 106 8
JNK2 95 4
JNK3 97 5
p38 alpha MAPK 107 6
p38 beta MAPK 72 7
p38 gamma MAPK 86 3
p38 delta MAPK 93 2
ERK8 57 10
RSK1 89 3
RSK2 88 2
PDK1 33 0
PKB alpha 82 14
PKB beta 104 0
SGK1 75 5
S6K1 100 7
PKA 99 1
ROCK 2 77 4
PRK2 71 1
PKC alpha 98 1
PKC zeta 82 5
PKD1 85 15
MSK1 91 0
MNK1 88 13
MNK2 71 5
MAPKAP-K2 102 7
MAPKAP-K3 106 4
PRAK 82 14
CAMKK alpha 89 13
CAMKK beta 62 9
CAMK1 71 4
SmMLCK 103 4
PHK 101 1
CHK1 71 4
CHK2 99 2
GSK3 beta 55 1
CDK2-Cyclin A 90 6
PLK1 96 7
Aurora B 6 2
Aurora C 8 0
AMPK 46 3
MARK3 35 3
BRSK2 72 3
MELK 56 10
CK1 delta 89 6
CK2 105 10
DYRK1A 86 3
DYRK2 92 0
DYRK3 86 9
NEK2a 94 3
NEK6 117 14
NEK7 116 14
IKK beta 95 9
IKK epsilon 37 4
TBK1 31 1
PIM1 86 1
PIM2 104 9
PIM3 97 2
SRPK1 79 8
EF2K 110 7
HIPK2 96 8
HIPK3 101 6
PAK4 78 7
PAK5 93 1
PAK6 88 2
MST2 97 3
MST4 102 3
Src 84 0
Lck 76 4
CSK 93 14
YES1 100 2
SYK 109 11
EPH-A2 81 5
FGF-R1 44 3
IRR 88 1

Do you need any help? Please get in touch and we’ll be happy to lend a hand.