Kinase Profiling Inhibitor Database

Inhibitor Structure Image Brutto MW Action Reference Reference 2 Patent Commercial Vendor Notes Results
BMS345541 (IKK Inhibitor III) C14H17N5 255.32 IKBKB Du Z. (2012) J Interferon Cytokine Res. 368-77 DE4329970 Merck (Calbiochem) Download

Results as Barchart

View results as a bar chart
1µM
10µM

Results as Table

Screening Concentration: 10µM
Kinase % Activity Remaining Standard Deviation
MKK1 96 3
ERK1 87 6
ERK2 97 2
JNK1 101 0
JNK2 83 2
JNK3 81 3
p38 alpha MAPK 101 3
p38 beta MAPK 101 2
p38 gamma MAPK 102 3
p38 delta MAPK 91 3
ERK8 18 2
RSK1 101 2
RSK2 81 8
PDK1 98 6
PKB alpha 88 5
PKB beta 103 1
SGK1 91 4
S6K1 83 3
PKA 94 4
ROCK 2 80 5
PRK2 100 3
PKC alpha 90 4
PKC zeta 102 8
PKD1 54 5
MSK1 82 2
MNK1 88 3
MNK2 100 6
MAPKAP-K2 100 3
MAPKAP-K3 94 3
PRAK 111 7
CAMKK beta 99 1
CAMK1 73 8
SmMLCK 77 2
PHK 88 4
DAPK1 118 45
CHK1 86 3
CHK2 88 2
GSK3 beta 82 7
CDK2-Cyclin A 60 4
PLK1 116 2
Aurora A 108 3
Aurora B 64 7
LKB1 71 8
AMPK 91 1
MARK1 110 3
MARK2 103 5
MARK3 109 11
MARK4 103 10
BRSK1 89 21
BRSK2 84 4
MELK 94 13
NUAK1 45 5
CK1 delta 55 5
CK2 79 1
DYRK1A 77 3
DYRK2 46 0
DYRK3 71 2
NEK2a 90 7
NEK6 86 7
IKK beta 16 6
IKK epsilon 101 8
TBK1 89 9
PIM1 95 2
PIM2 83 5
PIM3 70 3
SRPK1 104 4
EF2K 99 3
HIPK1 96 14
HIPK2 67 1
HIPK3 96 9
CLK2 74 3
PAK2 110 1
PAK4 106 7
PAK5 97 7
PAK6 96 7
MST2 92 7
MST4 89 5
GCK 87 5
MINK1 93 7
MEKK1 92 3
MLK1 89 6
MLK3 91 2
TAK1 101 13
IRAK4 97 7
RIPK2 113 19
TTK 85 4
Src 90 7
Lck 79 4
CSK 93 6
YES1 84 12
BTK 98 15
JAK2 87 2
SYK 96 1
EPH-A2 65 0
EPH-A4 83 1
EPH-B2 92 12
EPH-B3 61 1
EPH-B4 132 13
FGF-R1 73 18
HER4 105 9
IGF-1R 93 2
IR 109 1
IRR 76 3
TrkA 99 8
VEGFR1 69 2
Screening Concentration: 1µM
Kinase % Activity Remaining Standard Deviation
MKK1 113 10
ERK1 121 7
ERK2 116 23
JNK1 111 19
JNK2 116 2
JNK3 104 20
p38 alpha MAPK 113 16
p38 beta MAPK 100 4
p38 gamma MAPK 114 9
p38 delta MAPK 101 2
ERK8 93 5
RSK1 97 3
RSK2 109 5
PDK1 107 2
PKB alpha 92 0
PKB beta 117 14
SGK1 102 17
S6K1 105 1
PKA 112 6
ROCK 2 110 2
PRK2 116 8
PKC alpha 96 13
PKC zeta 124 2
PKD1 110 7
MSK1 93 7
MNK1 97 22
MNK2 119 3
MAPKAP-K2 111 3
MAPKAP-K3 129 15
PRAK 93 8
CAMKK beta 105 1
CAMK1 85 26
SmMLCK 110 7
PHK 109 3
DAPK1 109 8
CHK1 129 19
CHK2 121 7
GSK3 beta 102 19
CDK2-Cyclin A 97 9
PLK1 111 9
Aurora A 117 6
Aurora B 107 35
LKB1 99 6
AMPK 97 4
MARK1 109 2
MARK2 118 6
MARK3 97 11
MARK4 107 3
BRSK1 102 8
BRSK2 103 6
MELK 103 5
NUAK1 97 5
CK1 delta 104 19
CK2 116 8
DYRK1A 108 2
DYRK2 89 8
DYRK3 107 1
NEK2a 117 3
NEK6 105 0
IKK beta 57 2
IKK epsilon 119 13
TBK1 111 2
PIM1 105 1
PIM2 113 1
PIM3 87 4
SRPK1 111 3
EF2K 117 12
HIPK1 101 9
HIPK2 98 3
HIPK3 106 4
CLK2 102 12
PAK2 113 9
PAK4 139 28
PAK5 139 14
PAK6 103 11
MST2 86 8
MST4 94 1
GCK 110 3
MINK1 117 25
MEKK1 101 2
MLK1 104 34
MLK3 123 16
TAK1 105 10
IRAK4 127 19
RIPK2 102 4
TTK 102 8
Src 135 27
Lck 109 9
CSK 135 1
YES1 115 7
BTK 105 17
JAK2 111 12
SYK 97 1
EPH-A2 98 11
EPH-A4 103 7
EPH-B2 126 9
EPH-B3 97 5
EPH-B4 111 9
FGF-R1 103 12
HER4 145 13
IGF-1R 81 3
IR 109 1
IRR 94 3
TrkA 169 18
VEGFR1 94 4

Do you need any help? Please get in touch and we’ll be happy to lend a hand.