Kinase Profiling Inhibitor Database

Inhibitor Structure Image Brutto MW Action Reference Reference 2 Patent Commercial Vendor Notes Results
Blebbistatin C18H16N2O2 292.3 myosin II Shu S. (2005) Proc. Natl. Acad. Sci. USA 102 1472 Kovacs M. (2004) J. Biol. Chem. 279 35557 WO2012062819 Merck (Calbiochem) Download

Results as Barchart

View results as a bar chart
100µM
10µM

Results as Table

Screening Concentration: 10µM
Kinase % Activity Remainingsort ascending Standard Deviation
FGF-R1 118 14
EPH-B2 116 3
CDK2-Cyclin A 116 1
PHK 114 0
CK2 110 5
EPH-A2 109 8
EPH-A4 108 13
PKC zeta 108 5
NEK6 107 4
EPH-B3 107 4
Lck 106 6
BRSK1 106 5
SYK 105 12
MNK2 104 3
MST2 104 1
TrkA 103 3
PKC alpha 103 4
HIPK3 103 5
ERK1 102 1
JAK2 101 13
SGK1 101 0
MLK1 101 8
PKA 101 6
p38 alpha MAPK 101 2
MEKK1 100 8
CHK2 100 12
MST4 99 1
CK1 delta 99 4
EPH-B4 99 2
JNK3 99 2
PLK1 99 8
p38 gamma MAPK 99 2
Aurora A 99 3
DYRK3 99 9
BRSK2 98 4
HIPK2 98 0
MNK1 97 2
GCK 97 8
EPH-B1 97 11
NUAK1 97 3
DYRK1A 97 4
PKD1 97 11
IKK beta 96 4
YES1 96 2
MARK1 96 2
MELK 96 3
TAK1 96 3
PKB alpha 95 1
PRK2 95 0
IR 95 15
TBK1 94 6
MARK4 94 5
MKK6 94 0
PDK1 93 3
MARK2 93 1
PIM2 93 3
DAPK1 93 1
AMPK 92 8
S6K1 92 3
JNK1 92 2
MARK3 91 4
ERK2 91 9
ASK1 91 3
CAMKK beta 90 3
CHK1 90 5
RIPK2 90 7
PAK4 90 8
ERK8 89 5
MKK1 89 6
Aurora B 88 2
IRR 88 7
SRPK1 88 1
HIPK1 88 5
JNK2 88 6
GSK3 beta 88 0
IGF-1R 88 2
PIM1 87 6
CLK2 87 5
HER4 87 8
PAK2 87 5
TTK 87 3
MAPKAP-K3 86 1
IRAK4 86 6
VEGFR1 85 2
IKK epsilon 85 6
PAK6 83 6
PIM3 83 7
EF2K 83 5
MSK1 83 0
MAPKAP-K2 82 4
BTK 82 9
PRAK 82 3
TAO1 82 5
p38 beta MAPK 82 1
p38 delta MAPK 81 1
LKB1 81 1
MKK2 81 13
Src 80 6
NEK2a 77 2
ROCK 2 77 4
RSK1 76 1
DYRK2 76 10
PKB beta 74 6
CAMK1 74 4
SmMLCK 74 15
PAK5 73 7
MLK3 73 7
RSK2 72 3
MINK1 72 9
CSK 69 7
Screening Concentration: 100µM
Kinase % Activity Remainingsort ascending Standard Deviation
p38 delta MAPK 116 4
CK2 101 5
MKK1 99 6
CHK1 96 7
CDK2-Cyclin A 92 7
CK1 delta 91 3
DYRK1A 90 3
PKB alpha 88 3
PHK 86 2
NEK6 85 2
NEK2a 82 6
ERK2 82 3
MAPKAP-K2 80 4
p38 alpha MAPK 80 1
p38 gamma MAPK 80 0
JNK1 78 5
RSK1 77 5
ROCK 2 76 0
PKC alpha 75 7
MSK1 75 7
PDK1 74 3
Lck 72 1
S6K1 71 4
p38 beta MAPK 71 7
PKA 70 0
CSK 67 9
GSK3 beta 66 2
PRAK 64 1
SGK1 60 3
AMPK 60 2

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