Kinase Profiling Inhibitor Database

Inhibitor Structure Image Brutto MW Action Reference Reference 2 Patent Commercial Vendor Notes Results
Blebbistatin C18H16N2O2 292.3 myosin II Shu S. (2005) Proc. Natl. Acad. Sci. USA 102 1472 Kovacs M. (2004) J. Biol. Chem. 279 35557 WO2012062819 Merck (Calbiochem) Download

Results as Barchart

View results as a bar chart
100µM
10µM

Results as Table

Screening Concentration: 10µM
Kinase % Activity Remaining Standard Deviation
MKK1 89 6
MKK2 81 13
MKK6 94 0
ERK1 102 1
ERK2 91 9
JNK1 92 2
JNK2 88 6
JNK3 99 2
p38 alpha MAPK 101 2
p38 beta MAPK 82 1
p38 gamma MAPK 99 2
p38 delta MAPK 81 1
ERK8 89 5
RSK1 76 1
RSK2 72 3
PDK1 93 3
PKB alpha 95 1
PKB beta 74 6
SGK1 101 0
S6K1 92 3
PKA 101 6
ROCK 2 77 4
PRK2 95 0
PKC alpha 103 4
PKC zeta 108 5
PKD1 97 11
MSK1 83 0
MNK1 97 2
MNK2 104 3
MAPKAP-K2 82 4
MAPKAP-K3 86 1
PRAK 82 3
CAMKK beta 90 3
CAMK1 74 4
SmMLCK 74 15
PHK 114 0
DAPK1 93 1
CHK1 90 5
CHK2 100 12
GSK3 beta 88 0
CDK2-Cyclin A 116 1
PLK1 99 8
Aurora A 99 3
Aurora B 88 2
LKB1 81 1
AMPK 92 8
MARK1 96 2
MARK2 93 1
MARK3 91 4
MARK4 94 5
BRSK1 106 5
BRSK2 98 4
MELK 96 3
NUAK1 97 3
CK1 delta 99 4
CK2 110 5
DYRK1A 97 4
DYRK2 76 10
DYRK3 99 9
NEK2a 77 2
NEK6 107 4
IKK beta 96 4
IKK epsilon 85 6
TBK1 94 6
PIM1 87 6
PIM2 93 3
PIM3 83 7
SRPK1 88 1
EF2K 83 5
HIPK1 88 5
HIPK2 98 0
HIPK3 103 5
CLK2 87 5
PAK2 87 5
PAK4 90 8
PAK5 73 7
PAK6 83 6
MST2 104 1
MST4 99 1
GCK 97 8
MINK1 72 9
MEKK1 100 8
MLK1 101 8
MLK3 73 7
TAO1 82 5
ASK1 91 3
TAK1 96 3
IRAK4 86 6
RIPK2 90 7
TTK 87 3
Src 80 6
Lck 106 6
CSK 69 7
YES1 96 2
BTK 82 9
JAK2 101 13
SYK 105 12
EPH-A2 109 8
EPH-A4 108 13
EPH-B1 97 11
EPH-B2 116 3
EPH-B3 107 4
EPH-B4 99 2
FGF-R1 118 14
HER4 87 8
IGF-1R 88 2
IR 95 15
IRR 88 7
TrkA 103 3
VEGFR1 85 2
Screening Concentration: 100µM
Kinase % Activity Remaining Standard Deviation
MKK1 99 6
ERK2 82 3
JNK1 78 5
p38 alpha MAPK 80 1
p38 beta MAPK 71 7
p38 gamma MAPK 80 0
p38 delta MAPK 116 4
RSK1 77 5
PDK1 74 3
PKB alpha 88 3
SGK1 60 3
S6K1 71 4
PKA 70 0
ROCK 2 76 0
PKC alpha 75 7
MSK1 75 7
MAPKAP-K2 80 4
PRAK 64 1
PHK 86 2
CHK1 96 7
GSK3 beta 66 2
CDK2-Cyclin A 92 7
AMPK 60 2
CK1 delta 91 3
CK2 101 5
DYRK1A 90 3
NEK2a 82 6
NEK6 85 2
Lck 72 1
CSK 67 9

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