Kinase Profiling Inhibitor Database

Inhibitor Structure Image Brutto MW Action Reference Reference 2 Patent Commercial Vendor Notes Results
BAY439006 (Sorafenib, Nexavar) C21H16ClF3N4O3 464.8 Raf Lyons J.F. (2001) Endocrine Related Cancer 8 3 219-225 Wilhelm S.M. (2004) Cancer Res. 64(19) 7099-109 WO2002085857 Axon Download

Results as Barchart

View results as a bar chart
10µM

Results as Table

Screening Concentration: 10µM
Kinase % Activity Remainingsort ascending Standard Deviation
MAPKAP-K2 104 5
JNK3 101 4
EF2K 99 1
CK1 delta 99 3
CHK2 99 0
PIM2 98 1
CAMKK alpha 97 1
NEK7 96 4
CK2 95 3
PKB alpha 94 1
PAK6 94 2
IKK beta 94 0
PLK1 93 1
MAPKAP-K3 92 1
ERK1 92 7
NEK2a 92 5
NEK6 92 9
PKC zeta 92 4
MST2 91 4
ERK2 91 3
SGK1 90 3
PHK 90 2
PKD1 90 1
AMPK 89 4
PAK4 89 4
PAK5 89 3
CHK1 89 5
SRPK1 88 5
CAMKK beta 88 3
PKC alpha 87 1
PRAK 84 4
SmMLCK 84 1
MSK1 84 2
MARK3 83 0
PKB beta 83 1
JNK1 83 5
PDK1 82 2
DYRK1A 82 8
DYRK2 81 4
BRSK2 80 2
CDK2-Cyclin A 80 7
PRK2 79 1
S6K1 76 4
MKK1 74 3
PKA 72 3
PIM1 72 2
ROCK 2 71 8
p38 gamma MAPK 68 1
MNK1 67 5
PIM3 65 8
JNK2 65 4
GSK3 beta 64 1
CSK 63 3
p38 delta MAPK 61 4
MELK 56 5
RSK2 54 3
CAMK1 53 3
DYRK3 47 8
Src 44 1
RSK1 41 4
MNK2 40 2
Aurora C 34 1
Lck 27 0
p38 beta MAPK 22 4
HIPK3 21 2
Aurora B 15 1
HIPK2 14 1
p38 alpha MAPK 14 2
ERK8 7 2

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