Kinase Profiling Inhibitor Database

Inhibitor Structure Image Brutto MW Action Reference Reference 2 Patent Commercial Vendor Notes Results
BAY439006 (Sorafenib, Nexavar) C21H16ClF3N4O3 464.8 Raf Lyons J.F. (2001) Endocrine Related Cancer 8 3 219-225 Wilhelm S.M. (2004) Cancer Res. 64(19) 7099-109 WO2002085857 Axon Download

Results as Barchart

View results as a bar chart
10µM

Results as Table

Screening Concentration: 10µM
Kinase % Activity Remaining Standard Deviation
MKK1 74 3
ERK1 92 7
ERK2 91 3
JNK1 83 5
JNK2 65 4
JNK3 101 4
p38 alpha MAPK 14 2
p38 beta MAPK 22 4
p38 gamma MAPK 68 1
p38 delta MAPK 61 4
ERK8 7 2
RSK1 41 4
RSK2 54 3
PDK1 82 2
PKB alpha 94 1
PKB beta 83 1
SGK1 90 3
S6K1 76 4
PKA 72 3
ROCK 2 71 8
PRK2 79 1
PKC alpha 87 1
PKC zeta 92 4
PKD1 90 1
MSK1 84 2
MNK1 67 5
MNK2 40 2
MAPKAP-K2 104 5
MAPKAP-K3 92 1
PRAK 84 4
CAMKK alpha 97 1
CAMKK beta 88 3
CAMK1 53 3
SmMLCK 84 1
PHK 90 2
CHK1 89 5
CHK2 99 0
GSK3 beta 64 1
CDK2-Cyclin A 80 7
PLK1 93 1
Aurora B 15 1
Aurora C 34 1
AMPK 89 4
MARK3 83 0
BRSK2 80 2
MELK 56 5
CK1 delta 99 3
CK2 95 3
DYRK1A 82 8
DYRK2 81 4
DYRK3 47 8
NEK2a 92 5
NEK6 92 9
NEK7 96 4
IKK beta 94 0
PIM1 72 2
PIM2 98 1
PIM3 65 8
SRPK1 88 5
EF2K 99 1
HIPK2 14 1
HIPK3 21 2
PAK4 89 4
PAK5 89 3
PAK6 94 2
MST2 91 4
Src 44 1
Lck 27 0
CSK 63 3

Do you need any help? Please get in touch and we’ll be happy to lend a hand.