Kinase Profiling Inhibitor Database

Inhibitor Structure Image Brutto MW Action Reference Reference 2 Patent Commercial Vendor Notes Results
BAY-11-7082 C10H9NO2S 207.2 NFKBIA Kamthong P.J. (2001) Biochem. J. 356 Izban K.F. (2000) Hum. Pathol. 31 1482 WO2003072038 Merck (Calbiochem) Download

Results as Barchart

View results as a bar chart
1µM
10µM

Results as Table

Screening Concentration: 10µM
Kinase % Activity Remainingsort descending Standard Deviation
RSK2 8 0
PKB beta 8 1
Aurora A 14 0
CAMK1 19 2
NUAK1 20 1
MINK1 27 4
IKK epsilon 35 1
VEGFR1 40 9
BRSK2 41 7
MST2 51 5
BTK 58 6
MARK4 58 3
MST4 61 6
GCK 67 6
HER4 68 2
PRK2 70 5
MARK2 70 1
PIM1 71 3
PKD1 72 5
DAPK1 73 6
BRSK1 73 6
PKC alpha 75 0
LKB1 75 4
MAPKAP-K3 75 0
TBK1 75 6
EPH-A2 75 7
AMPK 76 4
PRAK 76 3
JNK2 78 5
DYRK2 78 5
SYK 78 1
MLK1 78 2
ERK2 79 2
CHK1 79 2
MSK1 79 5
RIPK2 80 0
PAK6 80 7
TAO1 81 3
ROCK 2 82 7
HIPK1 82 4
PIM3 82 1
JNK3 83 0
PAK2 83 5
PIM2 83 7
JAK2 84 3
S6K1 84 2
EF2K 85 4
MKK6 85 1
SmMLCK 85 9
CHK2 86 0
DYRK1A 86 3
TTK 86 3
RSK1 86 1
EPH-B4 87 5
CDK2-Cyclin A 87 8
p38 beta MAPK 87 4
IRR 87 3
TrkA 87 7
IKK beta 87 2
HIPK3 88 7
p38 alpha MAPK 88 7
NEK2a 88 10
PKA 89 6
MELK 89 13
MNK1 89 1
PAK5 89 8
MKK2 89 7
PDK1 90 4
PKB alpha 90 4
SRPK1 90 2
IRAK4 92 2
FGF-R1 92 11
PKC zeta 92 2
NEK6 92 1
CSK 92 10
MAPKAP-K2 92 0
MKK1 92 11
PLK1 93 5
p38 delta MAPK 93 1
MLK3 93 8
MEKK1 94 6
EPH-B1 94 3
IGF-1R 95 2
PAK4 95 10
MARK3 95 7
EPH-A4 95 4
HIPK2 96 5
CLK2 96 6
DYRK3 96 3
MNK2 96 11
EPH-B3 97 6
CK1 delta 97 6
p38 gamma MAPK 97 6
JNK1 99 1
TAK1 99 6
CAMKK beta 99 1
SGK1 99 6
MARK1 100 1
ASK1 101 5
GSK3 beta 101 3
Aurora B 101 14
ERK8 101 6
ERK1 102 8
CK2 104 4
IR 105 10
PHK 106 5
Lck 107 4
EPH-B2 112 4
YES1 158 14
Src 162 6
Screening Concentration: 1µM
Kinase % Activity Remainingsort descending Standard Deviation
CAMK1 59 13
PIM3 74 6
IGF-1R 77 40
RSK2 79 2
MARK2 80 11
BRSK1 80 11
VEGFR1 80 1
p38 beta MAPK 81 15
BTK 81 3
Aurora B 82 12
PKD1 83 1
PAK4 83 10
ERK2 84 5
CDK2-Cyclin A 84 4
JNK2 85 3
PKB beta 86 15
MLK1 86 13
PAK6 87 4
MEKK1 88 2
SGK1 88 10
MAPKAP-K3 89 8
MST4 89 6
MARK3 90 3
FGF-R1 90 5
HIPK3 90 3
MST2 90 16
PDK1 91 4
PHK 91 3
PKA 91 0
JNK1 91 7
EPH-B3 92 1
MLK3 93 7
NUAK1 93 5
GSK3 beta 93 6
LKB1 93 1
MAPKAP-K2 93 7
TBK1 94 1
AMPK 94 5
SYK 94 3
MARK4 95 1
IRAK4 95 1
PKC alpha 95 6
MSK1 95 6
p38 delta MAPK 95 8
MNK2 95 3
ROCK 2 96 7
DYRK1A 96 16
DYRK2 96 0
PAK2 96 15
HIPK2 97 4
PAK5 97 7
PRAK 98 13
EPH-A2 98 6
CSK 98 2
RSK1 98 11
CHK2 99 6
IR 99 7
IRR 99 1
JAK2 99 9
S6K1 100 16
PRK2 100 0
p38 alpha MAPK 100 13
PKC zeta 100 10
NEK6 100 12
EPH-B2 101 8
MELK 101 6
CK1 delta 101 3
IKK beta 101 10
PKB alpha 102 4
CAMKK beta 102 6
GCK 103 1
MINK1 103 3
PIM2 103 9
EF2K 103 13
CK2 103 2
CLK2 103 1
Aurora A 103 14
IKK epsilon 103 1
PIM1 104 5
SmMLCK 104 13
NEK2a 104 0
MARK1 104 2
MKK1 105 8
EPH-A4 106 1
BRSK2 106 4
SRPK1 107 6
DAPK1 107 13
JNK3 107 20
TTK 107 14
TAK1 108 24
HIPK1 108 18
PLK1 108 1
Lck 108 10
DYRK3 108 3
RIPK2 109 1
ERK8 110 7
p38 gamma MAPK 112 9
CHK1 113 18
HER4 117 11
MNK1 117 16
ERK1 121 5
TrkA 124 5
EPH-B4 125 4
YES1 127 34
Src 177 4

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