Kinase Profiling Inhibitor Database

Inhibitor Structure Image Brutto MW Action Reference Reference 2 Patent Commercial Vendor Notes Results
Bay 65-1942 C22H26ClN3O4 431.91 IKKb Ziegelbauer K. (2005) British Journal of Pharmacology 145 178-192 (compound A) Moss N.C. (2007) Am J Physiol Heart Circ Physiol 293 H2248-53 AdooQ Bioscience Download

Results as Barchart

View results as a bar chart
1µM
10µM

Results as Table

Screening Concentration: 10µM
Kinase % Activity Remainingsort ascending Standard Deviation
MAPKAP-K2 147 91
VEGFR1 116 1
PDK1 100 7
GSK3 beta 99 6
IR 96 9
MARK3 94 2
NEK6 93 11
JNK2 93 5
EPH-B3 93 9
CSK 92 5
SYK 91 17
CHK1 88 4
PLK1 87 2
MNK2 87 7
ERK1 86 3
MST4 85 13
EPH-A2 84 3
TBK1 84 4
BTK 83 0
Src 83 1
DYRK1A 82 6
NEK2a 81 8
FGF-R1 79 2
CAMKK beta 78 9
p38 alpha MAPK 78 7
PAK6 78 1
DYRK2 77 9
Lck 74 4
ERK2 74 14
p38 beta MAPK 74 12
MNK1 74 5
IKK epsilon 74 6
p38 delta MAPK 73 4
PAK5 72 1
IGF-1R 71 29
CK2 70 0
S6K1 68 0
MST2 67 2
EF2K 67 0
p38 gamma MAPK 66 2
PKA 65 4
SRPK1 65 5
MKK1 62 7
PKB beta 61 3
JNK1 61 0
MELK 58 17
PRAK 58 13
PKB alpha 55 15
AMPK 54 5
PAK4 54 8
RSK2 53 3
YES1 49 4
PKD1 48 1
CHK2 46 7
RSK1 46 2
IRR 45 4
BRSK2 45 4
CK1 delta 43 3
PIM2 40 12
ROCK 2 39 0
SmMLCK 37 5
PRK2 36 0
HIPK2 34 3
PKC alpha 31 5
MSK1 31 2
DYRK3 24 1
PHK 21 1
PIM1 15 0
CDK2-Cyclin A 14 0
CAMK1 13 0
SGK1 13 0
IKK beta 12 1
PKC zeta 10 1
ERK8 10 1
PIM3 7 1
Screening Concentration: 1µM
Kinase % Activity Remainingsort ascending Standard Deviation
GSK3 beta 126 6
MAPKAP-K2 120 37
VEGFR1 112 2
PDK1 106 3
SYK 106 13
MST4 105 4
S6K1 102 17
CHK1 102 4
MARK3 100 8
BTK 100 7
DYRK1A 99 3
DYRK2 99 8
MNK2 98 5
NEK6 98 3
ERK1 98 22
SRPK1 98 6
MNK1 97 8
FGF-R1 96 6
EPH-A2 96 7
CK2 95 7
IR 94 1
CAMKK beta 94 0
YES1 94 2
TBK1 91 2
Src 91 3
CSK 91 11
p38 alpha MAPK 91 0
p38 beta MAPK 91 1
JNK2 90 6
BRSK2 89 2
PAK4 89 13
EPH-B3 89 13
p38 delta MAPK 88 7
Lck 88 4
PKB beta 88 11
PIM2 88 24
EF2K 88 6
PKB alpha 87 1
AMPK 87 0
p38 gamma MAPK 85 0
HIPK2 84 4
MST2 84 3
RSK1 83 0
IKK epsilon 83 0
NEK2a 83 6
PLK1 83 7
PAK5 82 1
CK1 delta 81 5
ERK2 81 0
RSK2 80 8
IGF-1R 80 18
MELK 79 23
MKK1 79 0
PKA 79 6
PKD1 79 1
IRR 78 6
CHK2 77 6
PKC alpha 77 7
SmMLCK 76 6
PIM1 76 7
JNK1 76 4
PKC zeta 76 47
PRAK 74 1
ROCK 2 73 0
PAK6 72 1
MSK1 71 4
DYRK3 71 7
PHK 70 8
PRK2 69 7
CDK2-Cyclin A 58 5
SGK1 55 4
CAMK1 54 3
ERK8 53 1
PIM3 44 2
IKK beta 28 17

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