Kinase Profiling Inhibitor Database

Inhibitor Structure Image Brutto MW Action Reference Reference 2 Patent Commercial Vendor Notes Results
Bay 65-1942 C22H26ClN3O4 431.91 IKKb Ziegelbauer K. (2005) British Journal of Pharmacology 145 178-192 (compound A) Moss N.C. (2007) Am J Physiol Heart Circ Physiol 293 H2248-53 AdooQ Bioscience Download

Results as Barchart

View results as a bar chart
1µM
10µM

Results as Table

Screening Concentration: 10µM
Kinase % Activity Remainingsort descending Standard Deviation
PIM3 7 1
PKC zeta 10 1
ERK8 10 1
IKK beta 12 1
SGK1 13 0
CAMK1 13 0
CDK2-Cyclin A 14 0
PIM1 15 0
PHK 21 1
DYRK3 24 1
PKC alpha 31 5
MSK1 31 2
HIPK2 34 3
PRK2 36 0
SmMLCK 37 5
ROCK 2 39 0
PIM2 40 12
CK1 delta 43 3
IRR 45 4
BRSK2 45 4
CHK2 46 7
RSK1 46 2
PKD1 48 1
YES1 49 4
RSK2 53 3
AMPK 54 5
PAK4 54 8
PKB alpha 55 15
MELK 58 17
PRAK 58 13
PKB beta 61 3
JNK1 61 0
MKK1 62 7
PKA 65 4
SRPK1 65 5
p38 gamma MAPK 66 2
MST2 67 2
EF2K 67 0
S6K1 68 0
CK2 70 0
IGF-1R 71 29
PAK5 72 1
p38 delta MAPK 73 4
ERK2 74 14
p38 beta MAPK 74 12
MNK1 74 5
IKK epsilon 74 6
Lck 74 4
DYRK2 77 9
p38 alpha MAPK 78 7
PAK6 78 1
CAMKK beta 78 9
FGF-R1 79 2
NEK2a 81 8
DYRK1A 82 6
BTK 83 0
Src 83 1
EPH-A2 84 3
TBK1 84 4
MST4 85 13
ERK1 86 3
PLK1 87 2
MNK2 87 7
CHK1 88 4
SYK 91 17
CSK 92 5
NEK6 93 11
JNK2 93 5
EPH-B3 93 9
MARK3 94 2
IR 96 9
GSK3 beta 99 6
PDK1 100 7
VEGFR1 116 1
MAPKAP-K2 147 91
Screening Concentration: 1µM
Kinase % Activity Remainingsort descending Standard Deviation
IKK beta 28 17
PIM3 44 2
ERK8 53 1
CAMK1 54 3
SGK1 55 4
CDK2-Cyclin A 58 5
PRK2 69 7
PHK 70 8
DYRK3 71 7
MSK1 71 4
PAK6 72 1
ROCK 2 73 0
PRAK 74 1
SmMLCK 76 6
PIM1 76 7
JNK1 76 4
PKC zeta 76 47
CHK2 77 6
PKC alpha 77 7
IRR 78 6
MKK1 79 0
PKA 79 6
PKD1 79 1
MELK 79 23
RSK2 80 8
IGF-1R 80 18
CK1 delta 81 5
ERK2 81 0
PAK5 82 1
RSK1 83 0
IKK epsilon 83 0
NEK2a 83 6
PLK1 83 7
MST2 84 3
HIPK2 84 4
p38 gamma MAPK 85 0
PKB alpha 87 1
AMPK 87 0
Lck 88 4
PKB beta 88 11
PIM2 88 24
EF2K 88 6
p38 delta MAPK 88 7
BRSK2 89 2
PAK4 89 13
EPH-B3 89 13
JNK2 90 6
TBK1 91 2
Src 91 3
CSK 91 11
p38 alpha MAPK 91 0
p38 beta MAPK 91 1
CAMKK beta 94 0
YES1 94 2
IR 94 1
CK2 95 7
FGF-R1 96 6
EPH-A2 96 7
MNK1 97 8
MNK2 98 5
NEK6 98 3
ERK1 98 22
SRPK1 98 6
DYRK1A 99 3
DYRK2 99 8
MARK3 100 8
BTK 100 7
S6K1 102 17
CHK1 102 4
MST4 105 4
PDK1 106 3
SYK 106 13
VEGFR1 112 2
MAPKAP-K2 120 37
GSK3 beta 126 6

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