Kinase Profiling Inhibitor Database

Inhibitor Structure Image Brutto MW Action Reference Reference 2 Patent Commercial Vendor Notes Results
AS601245 (JNK Inhibitor V) C20H16N6S 372.5 JNK Gaillard P. (2005) J. Med. Chem. 48 4596 Carboni S. (2005) J. Neurochem. 92 1054 WO2013152038 Merck (Calbiochem) Download

Results as Barchart

View results as a bar chart
1µM
10µM

Results as Table

Screening Concentration: 1µM
Kinase % Activity Remainingsort ascending Standard Deviation
PKA 112 8
EF2K 110 10
FGF-R1 109 13
PKD1 108 10
PLK1 106 7
MAPKAP-K3 105 8
ERK1 104 5
PDK1 102 6
PAK6 102 3
CAMK1 101 2
MST4 101 13
YES1 99 13
CSK 98 4
PRAK 97 8
CHK1 97 1
SRPK1 96 7
S6K1 96 4
p38 beta MAPK 96 5
PKB beta 95 7
CHK2 95 4
IKK beta 94 6
SYK 93 14
BRSK2 92 7
MELK 92 3
SGK1 92 3
CAMKK beta 91 7
ERK2 91 9
CAMKK alpha 90 11
SmMLCK 90 8
EPH-A2 90 14
RSK2 89 8
PKC alpha 89 6
MSK1 89 12
PRK2 88 12
TBK1 87 3
MARK3 86 9
PAK5 86 11
PKC zeta 86 4
CDK2-Cyclin A 86 6
MAPKAP-K2 85 7
PHK 85 3
NEK7 85 7
PAK4 84 11
NEK6 84 9
Aurora B 84 7
NEK2a 83 10
Lck 83 5
AMPK 82 7
JNK1 82 9
MST2 80 4
ROCK 2 80 3
IKK epsilon 79 1
Src 79 4
PKB alpha 78 4
p38 gamma MAPK 78 8
IRR 74 0
MKK1 73 6
JNK2 73 5
JNK3 72 5
p38 alpha MAPK 72 8
RSK1 71 6
CK1 delta 71 7
Aurora C 70 6
MNK2 70 6
p38 delta MAPK 68 10
MNK1 68 10
CK2 63 6
HIPK3 61 4
ERK8 48 3
PIM2 40 5
DYRK1A 33 3
HIPK2 29 3
DYRK3 24 3
DYRK2 12 1
PIM1 8 1
PIM3 3 1
GSK3 beta 2 1
Screening Concentration: 10µM
Kinase % Activity Remainingsort ascending Standard Deviation
EPH-A2 108 11
CAMK1 106 7
MST4 105 3
ERK1 97 3
MAPKAP-K3 96 5
CHK1 95 9
PDK1 92 9
SYK 92 11
EF2K 90 5
PAK6 89 11
p38 beta MAPK 87 8
IKK beta 86 3
MST2 86 3
PKC zeta 85 12
NEK2a 81 6
PKC alpha 80 7
IKK epsilon 78 6
PKA 77 8
CSK 77 6
BRSK2 73 6
SRPK1 72 1
NEK7 70 5
AMPK 70 4
SGK1 69 5
MSK1 69 5
ERK2 68 4
Lck 68 7
TBK1 67 2
PRAK 67 3
CAMKK alpha 67 8
MELK 66 7
S6K1 65 8
CHK2 64 5
NEK6 63 10
p38 alpha MAPK 63 1
PHK 62 6
CDK2-Cyclin A 62 5
PRK2 58 8
SmMLCK 57 5
Aurora B 57 5
YES1 57 8
PAK5 54 3
MAPKAP-K2 54 3
RSK2 52 6
CK1 delta 51 6
PKB beta 51 5
MKK1 51 6
MNK1 50 8
MARK3 50 7
FGF-R1 49 3
Aurora C 48 7
p38 gamma MAPK 46 4
JNK1 43 4
PLK1 43 6
CAMKK beta 41 4
JNK3 40 4
PKD1 40 11
RSK1 40 1
MNK2 39 4
PAK4 38 3
Src 38 3
PKB alpha 32 3
ROCK 2 32 7
JNK2 29 3
p38 delta MAPK 28 2
CK2 22 3
HIPK3 18 2
IRR 16 1
ERK8 12 2
DYRK1A 9 2
DYRK3 9 5
HIPK2 7 1
PIM2 7 2
PIM1 5 3
DYRK2 4 3
PIM3 2 0
GSK3 beta 1 1

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