Kinase Profiling Inhibitor Database

Inhibitor Structure Image Brutto MW Action Reference Reference 2 Patent Commercial Vendor Notes Results
AS601245 (JNK Inhibitor V) C20H16N6S 372.5 JNK Gaillard P. (2005) J. Med. Chem. 48 4596 Carboni S. (2005) J. Neurochem. 92 1054 WO2013152038 Merck (Calbiochem) Download

Results as Barchart

View results as a bar chart
1µM
10µM

Results as Table

Screening Concentration: 10µM
Kinase % Activity Remainingsort descending Standard Deviation
GSK3 beta 1 1
PIM3 2 0
DYRK2 4 3
PIM1 5 3
HIPK2 7 1
PIM2 7 2
DYRK1A 9 2
DYRK3 9 5
ERK8 12 2
IRR 16 1
HIPK3 18 2
CK2 22 3
p38 delta MAPK 28 2
JNK2 29 3
PKB alpha 32 3
ROCK 2 32 7
PAK4 38 3
Src 38 3
MNK2 39 4
RSK1 40 1
JNK3 40 4
PKD1 40 11
CAMKK beta 41 4
JNK1 43 4
PLK1 43 6
p38 gamma MAPK 46 4
Aurora C 48 7
FGF-R1 49 3
MARK3 50 7
MNK1 50 8
CK1 delta 51 6
PKB beta 51 5
MKK1 51 6
RSK2 52 6
MAPKAP-K2 54 3
PAK5 54 3
YES1 57 8
SmMLCK 57 5
Aurora B 57 5
PRK2 58 8
PHK 62 6
CDK2-Cyclin A 62 5
NEK6 63 10
p38 alpha MAPK 63 1
CHK2 64 5
S6K1 65 8
MELK 66 7
TBK1 67 2
PRAK 67 3
CAMKK alpha 67 8
ERK2 68 4
Lck 68 7
SGK1 69 5
MSK1 69 5
AMPK 70 4
NEK7 70 5
SRPK1 72 1
BRSK2 73 6
PKA 77 8
CSK 77 6
IKK epsilon 78 6
PKC alpha 80 7
NEK2a 81 6
PKC zeta 85 12
MST2 86 3
IKK beta 86 3
p38 beta MAPK 87 8
PAK6 89 11
EF2K 90 5
PDK1 92 9
SYK 92 11
CHK1 95 9
MAPKAP-K3 96 5
ERK1 97 3
MST4 105 3
CAMK1 106 7
EPH-A2 108 11
Screening Concentration: 1µM
Kinase % Activity Remainingsort descending Standard Deviation
GSK3 beta 2 1
PIM3 3 1
PIM1 8 1
DYRK2 12 1
DYRK3 24 3
HIPK2 29 3
DYRK1A 33 3
PIM2 40 5
ERK8 48 3
HIPK3 61 4
CK2 63 6
p38 delta MAPK 68 10
MNK1 68 10
Aurora C 70 6
MNK2 70 6
RSK1 71 6
CK1 delta 71 7
JNK3 72 5
p38 alpha MAPK 72 8
MKK1 73 6
JNK2 73 5
IRR 74 0
p38 gamma MAPK 78 8
PKB alpha 78 4
IKK epsilon 79 1
Src 79 4
MST2 80 4
ROCK 2 80 3
AMPK 82 7
JNK1 82 9
NEK2a 83 10
Lck 83 5
Aurora B 84 7
PAK4 84 11
NEK6 84 9
MAPKAP-K2 85 7
PHK 85 3
NEK7 85 7
MARK3 86 9
PAK5 86 11
PKC zeta 86 4
CDK2-Cyclin A 86 6
TBK1 87 3
PRK2 88 12
MSK1 89 12
RSK2 89 8
PKC alpha 89 6
EPH-A2 90 14
CAMKK alpha 90 11
SmMLCK 90 8
CAMKK beta 91 7
ERK2 91 9
BRSK2 92 7
MELK 92 3
SGK1 92 3
SYK 93 14
IKK beta 94 6
PKB beta 95 7
CHK2 95 4
p38 beta MAPK 96 5
SRPK1 96 7
S6K1 96 4
PRAK 97 8
CHK1 97 1
CSK 98 4
YES1 99 13
MST4 101 13
CAMK1 101 2
PDK1 102 6
PAK6 102 3
ERK1 104 5
MAPKAP-K3 105 8
PLK1 106 7
PKD1 108 10
FGF-R1 109 13
EF2K 110 10
PKA 112 8

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