Kinase Profiling Inhibitor Database

Inhibitor Structure Image Brutto MW Action Reference Reference 2 Patent Commercial Vendor Notes Results
AS601245 (JNK Inhibitor V) C20H16N6S 372.5 JNK Gaillard P. (2005) J. Med. Chem. 48 4596 Carboni S. (2005) J. Neurochem. 92 1054 WO2013152038 Merck (Calbiochem) Download

Results as Barchart

View results as a bar chart
1µM
10µM

Results as Table

Screening Concentration: 10µM
Kinase % Activity Remainingsort descending Standard Deviation
GSK3 beta 1 1
PIM3 2 0
DYRK2 4 3
PIM1 5 3
PIM2 7 2
HIPK2 7 1
DYRK1A 9 2
DYRK3 9 5
ERK8 12 2
IRR 16 1
HIPK3 18 2
CK2 22 3
p38 delta MAPK 28 2
JNK2 29 3
ROCK 2 32 7
PKB alpha 32 3
PAK4 38 3
Src 38 3
MNK2 39 4
JNK3 40 4
PKD1 40 11
RSK1 40 1
CAMKK beta 41 4
JNK1 43 4
PLK1 43 6
p38 gamma MAPK 46 4
Aurora C 48 7
FGF-R1 49 3
MNK1 50 8
MARK3 50 7
CK1 delta 51 6
PKB beta 51 5
MKK1 51 6
RSK2 52 6
MAPKAP-K2 54 3
PAK5 54 3
Aurora B 57 5
YES1 57 8
SmMLCK 57 5
PRK2 58 8
CDK2-Cyclin A 62 5
PHK 62 6
NEK6 63 10
p38 alpha MAPK 63 1
CHK2 64 5
S6K1 65 8
MELK 66 7
TBK1 67 2
PRAK 67 3
CAMKK alpha 67 8
Lck 68 7
ERK2 68 4
MSK1 69 5
SGK1 69 5
NEK7 70 5
AMPK 70 4
SRPK1 72 1
BRSK2 73 6
CSK 77 6
PKA 77 8
IKK epsilon 78 6
PKC alpha 80 7
NEK2a 81 6
PKC zeta 85 12
IKK beta 86 3
MST2 86 3
p38 beta MAPK 87 8
PAK6 89 11
EF2K 90 5
SYK 92 11
PDK1 92 9
CHK1 95 9
MAPKAP-K3 96 5
ERK1 97 3
MST4 105 3
CAMK1 106 7
EPH-A2 108 11
Screening Concentration: 1µM
Kinase % Activity Remainingsort descending Standard Deviation
GSK3 beta 2 1
PIM3 3 1
PIM1 8 1
DYRK2 12 1
DYRK3 24 3
HIPK2 29 3
DYRK1A 33 3
PIM2 40 5
ERK8 48 3
HIPK3 61 4
CK2 63 6
p38 delta MAPK 68 10
MNK1 68 10
Aurora C 70 6
MNK2 70 6
RSK1 71 6
CK1 delta 71 7
JNK3 72 5
p38 alpha MAPK 72 8
MKK1 73 6
JNK2 73 5
IRR 74 0
p38 gamma MAPK 78 8
PKB alpha 78 4
Src 79 4
IKK epsilon 79 1
ROCK 2 80 3
MST2 80 4
JNK1 82 9
AMPK 82 7
NEK2a 83 10
Lck 83 5
NEK6 84 9
Aurora B 84 7
PAK4 84 11
PHK 85 3
NEK7 85 7
MAPKAP-K2 85 7
PAK5 86 11
PKC zeta 86 4
CDK2-Cyclin A 86 6
MARK3 86 9
TBK1 87 3
PRK2 88 12
PKC alpha 89 6
MSK1 89 12
RSK2 89 8
SmMLCK 90 8
EPH-A2 90 14
CAMKK alpha 90 11
ERK2 91 9
CAMKK beta 91 7
SGK1 92 3
BRSK2 92 7
MELK 92 3
SYK 93 14
IKK beta 94 6
CHK2 95 4
PKB beta 95 7
S6K1 96 4
p38 beta MAPK 96 5
SRPK1 96 7
CHK1 97 1
PRAK 97 8
CSK 98 4
YES1 99 13
CAMK1 101 2
MST4 101 13
PAK6 102 3
PDK1 102 6
ERK1 104 5
MAPKAP-K3 105 8
PLK1 106 7
PKD1 108 10
FGF-R1 109 13
EF2K 110 10
PKA 112 8

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