Kinase Profiling Inhibitor Database

Inhibitor Structure Image Brutto MW Action Reference Reference 2 Patent Commercial Vendor Notes Results
AS601245 (JNK Inhibitor V) C20H16N6S 372.5 JNK Gaillard P. (2005) J. Med. Chem. 48 4596 Carboni S. (2005) J. Neurochem. 92 1054 WO2013152038 Merck (Calbiochem) Download

Results as Barchart

View results as a bar chart
1µM
10µM

Results as Table

Screening Concentration: 10µM
Kinase % Activity Remaining Standard Deviation
MKK1 51 6
ERK1 97 3
ERK2 68 4
JNK1 43 4
JNK2 29 3
JNK3 40 4
p38 alpha MAPK 63 1
p38 beta MAPK 87 8
p38 gamma MAPK 46 4
p38 delta MAPK 28 2
ERK8 12 2
RSK1 40 1
RSK2 52 6
PDK1 92 9
PKB alpha 32 3
PKB beta 51 5
SGK1 69 5
S6K1 65 8
PKA 77 8
ROCK 2 32 7
PRK2 58 8
PKC alpha 80 7
PKC zeta 85 12
PKD1 40 11
MSK1 69 5
MNK1 50 8
MNK2 39 4
MAPKAP-K2 54 3
MAPKAP-K3 96 5
PRAK 67 3
CAMKK alpha 67 8
CAMKK beta 41 4
CAMK1 106 7
SmMLCK 57 5
PHK 62 6
CHK1 95 9
CHK2 64 5
GSK3 beta 1 1
CDK2-Cyclin A 62 5
PLK1 43 6
Aurora B 57 5
Aurora C 48 7
AMPK 70 4
MARK3 50 7
BRSK2 73 6
MELK 66 7
CK1 delta 51 6
CK2 22 3
DYRK1A 9 2
DYRK2 4 3
DYRK3 9 5
NEK2a 81 6
NEK6 63 10
NEK7 70 5
IKK beta 86 3
IKK epsilon 78 6
TBK1 67 2
PIM1 5 3
PIM2 7 2
PIM3 2 0
SRPK1 72 1
EF2K 90 5
HIPK2 7 1
HIPK3 18 2
PAK4 38 3
PAK5 54 3
PAK6 89 11
MST2 86 3
MST4 105 3
Src 38 3
Lck 68 7
CSK 77 6
YES1 57 8
SYK 92 11
EPH-A2 108 11
FGF-R1 49 3
IRR 16 1
Screening Concentration: 1µM
Kinase % Activity Remaining Standard Deviation
MKK1 73 6
ERK1 104 5
ERK2 91 9
JNK1 82 9
JNK2 73 5
JNK3 72 5
p38 alpha MAPK 72 8
p38 beta MAPK 96 5
p38 gamma MAPK 78 8
p38 delta MAPK 68 10
ERK8 48 3
RSK1 71 6
RSK2 89 8
PDK1 102 6
PKB alpha 78 4
PKB beta 95 7
SGK1 92 3
S6K1 96 4
PKA 112 8
ROCK 2 80 3
PRK2 88 12
PKC alpha 89 6
PKC zeta 86 4
PKD1 108 10
MSK1 89 12
MNK1 68 10
MNK2 70 6
MAPKAP-K2 85 7
MAPKAP-K3 105 8
PRAK 97 8
CAMKK alpha 90 11
CAMKK beta 91 7
CAMK1 101 2
SmMLCK 90 8
PHK 85 3
CHK1 97 1
CHK2 95 4
GSK3 beta 2 1
CDK2-Cyclin A 86 6
PLK1 106 7
Aurora B 84 7
Aurora C 70 6
AMPK 82 7
MARK3 86 9
BRSK2 92 7
MELK 92 3
CK1 delta 71 7
CK2 63 6
DYRK1A 33 3
DYRK2 12 1
DYRK3 24 3
NEK2a 83 10
NEK6 84 9
NEK7 85 7
IKK beta 94 6
IKK epsilon 79 1
TBK1 87 3
PIM1 8 1
PIM2 40 5
PIM3 3 1
SRPK1 96 7
EF2K 110 10
HIPK2 29 3
HIPK3 61 4
PAK4 84 11
PAK5 86 11
PAK6 102 3
MST2 80 4
MST4 101 13
Src 79 4
Lck 83 5
CSK 98 4
YES1 99 13
SYK 93 14
EPH-A2 90 14
FGF-R1 109 13
IRR 74 0

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