Kinase Profiling Inhibitor Database

Inhibitor Structure Image Brutto MW Action Reference Reference 2 Patent Commercial Vendor Notes Results
Alsterpaullone C16H11N3O3 293.3 GSK3b, CDK5/p25, CDK1/cyclin B Leost M. (2000) Eur. J. Biochem. 267 5983 Schultz C. (1999) J. Med. Chem. 42 2909 EP20050109789 Merck (Calbiochem) Download

Results as Barchart

View results as a bar chart
1µM

Results as Table

Screening Concentration: 1µM
Kinase % Activity Remainingsort descending Standard Deviation
GSK3 beta 3 0
CDK2-Cyclin A 10 2
PHK 11 1
CHK2 13 4
YES1 22 1
SYK 31 6
PAK4 33 0
TBK1 35 2
BRSK2 37 4
IRR 37 5
PAK5 40 5
FGF-R1 46 9
PKC zeta 50 4
Lck 52 4
MST2 53 3
MELK 54 2
CAMK1 54 2
Src 61 2
PRK2 61 6
MARK3 63 5
PAK6 64 9
CHK1 64 4
IKK epsilon 66 8
RSK1 67 3
CAMKK beta 68 3
MAPKAP-K3 70 5
PDK1 71 5
AMPK 73 6
RSK2 73 7
MNK1 74 1
Aurora C 76 4
PRAK 76 0
HIPK2 77 2
PIM3 78 8
JNK3 78 0
Aurora B 78 3
MST4 78 1
SRPK1 79 7
ERK2 79 5
PKA 79 1
CAMKK alpha 80 3
PKC alpha 80 7
JNK2 81 4
PLK1 81 5
PIM1 81 5
JNK1 82 5
MSK1 82 6
DYRK1A 83 1
CSK 83 9
SGK1 85 1
p38 delta MAPK 86 0
MKK1 86 3
NEK6 86 1
p38 beta MAPK 86 2
ERK8 87 5
EF2K 87 4
DYRK2 87 3
ROCK 2 87 4
p38 gamma MAPK 87 5
PKB alpha 88 1
PKB beta 88 1
CK2 88 1
MNK2 90 4
IKK beta 90 2
EPH-A2 90 9
SmMLCK 91 4
PKD1 91 9
PIM2 91 5
NEK2a 92 2
NEK7 92 5
S6K1 93 1
DYRK3 93 9
MAPKAP-K2 95 4
HIPK3 95 1
ERK1 95 0
CK1 delta 98 4
p38 alpha MAPK 109 1

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