Kinase Profiling Inhibitor Database

Inhibitor Structure Image Brutto MW Action Reference Reference 2 Patent Commercial Vendor Notes Results
AG879 (Tyrphostin) C18H24N2OS 316.5 Tyrosine-kinases Konrad R.J. (1996) J. Biol. Chem. 271 24179 Levitzki A. Gazit A. (1995) Science 267 1782 WO2003068927 Merck (Calbiochem) Download

Results as Barchart

View results as a bar chart
0.1µM
10µM

Results as Table

Screening Concentration: 0.1µM
Kinase % Activity Remainingsort ascending Standard Deviation
PAK5 585 715
SYK 173 70
SGK1 124 15
CK2 123 8
FGF-R1 120 17
HIPK2 118 15
IR 118 7
ROCK 2 113 10
MST2 113 8
YES1 111 13
DYRK2 110 8
CDK2-Cyclin A 110 1
IKK beta 109 10
CHK2 109 23
MAPKAP-K2 108 11
PAK4 105 11
PLK1 105 9
p38 alpha MAPK 105 7
EF2K 105 4
PKB alpha 103 1
PRAK 102 2
PIM1 102 22
MNK1 101 4
PRK2 101 30
PKC alpha 101 10
PDK1 100 0
NEK6 100 24
RSK1 99 9
Lck 99 8
JNK1 99 9
PKD1 99 12
p38 gamma MAPK 98 7
DYRK3 98 11
PIM2 98 1
PIM3 98 19
IGF-1R 98 16
ERK8 96 2
EPH-B3 96 10
CK1 delta 95 0
Src 95 11
MKK1 95 1
GSK3 beta 95 7
EPH-A2 94 12
p38 delta MAPK 93 11
PHK 93 19
VEGFR1 92 3
CSK 92 15
S6K1 92 4
MARK3 92 6
ERK2 91 2
JNK2 90 10
TBK1 90 6
p38 beta MAPK 89 6
IRR 88 0
ERK1 88 16
BRSK2 87 9
PAK6 86 1
CHK1 86 1
SRPK1 86 0
PKC zeta 86 7
CAMK1 85 9
SmMLCK 85 20
NEK2a 85 17
PKA 85 3
MNK2 84 0
DYRK1A 84 1
PKB beta 84 3
MST4 83 0
MSK1 82 3
CAMKK beta 78 22
IKK epsilon 78 8
AMPK 78 0
MELK 76 1
RSK2 67 2
BTK 55 4
Screening Concentration: 10µM
Kinase % Activity Remainingsort ascending Standard Deviation
PAK5 519 649
IR 139 52
SYK 138 2
CK2 118 5
PRK2 114 16
EPH-A2 113 11
Lck 107 13
SGK1 107 13
IKK beta 105 13
DYRK2 102 31
NEK6 101 16
MNK1 99 8
MAPKAP-K2 99 2
TBK1 97 1
PDK1 96 5
CHK2 96 14
PKB alpha 94 4
ROCK 2 94 0
PKA 93 10
CHK1 92 19
p38 gamma MAPK 92 3
CK1 delta 92 6
ERK1 90 8
MARK3 90 7
EF2K 90 8
CSK 89 6
CAMK1 88 7
MSK1 88 3
ERK2 87 1
JNK1 87 16
p38 beta MAPK 86 8
IGF-1R 86 4
p38 delta MAPK 86 11
YES1 85 1
MKK1 83 13
NEK2a 82 18
p38 alpha MAPK 81 9
PKD1 80 3
PAK6 80 1
RSK1 79 1
PKC alpha 78 6
MNK2 76 9
MST4 72 14
JNK2 70 9
AMPK 70 2
PKC zeta 67 2
Src 67 0
BRSK2 66 4
S6K1 64 14
IKK epsilon 63 9
SRPK1 61 12
RSK2 61 4
DYRK3 60 1
FGF-R1 59 0
PAK4 56 2
DYRK1A 56 3
EPH-B3 55 1
MST2 54 1
PIM2 53 5
SmMLCK 52 5
VEGFR1 50 3
BTK 46 8
IRR 45 4
CAMKK beta 44 12
CDK2-Cyclin A 40 0
GSK3 beta 39 4
ERK8 37 0
PIM3 34 8
PHK 28 1
PRAK 27 2
PIM1 25 3
HIPK2 21 2
PKB beta 15 9
PLK1 13 2
MELK 8 4

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