Kinase Profiling Inhibitor Database

Inhibitor Structure Image Brutto MW Action Reference Reference 2 Patent Commercial Vendor Notes Results
A-443654 C24H23ON5x2HCl 470.39 Akt1 Shi Y. (2005) Neoplasia 7 992-1000. WO2007106884 AdooQ Bioscience Download

Results as Barchart

View results as a bar chart
0.01µM
0.1µM

Results as Table

Screening Concentration: 0.1µM
Kinase % Activity Remainingsort descending Standard Deviation
PKB beta 2 0
PRK2 2 2
PKB alpha 3 2
PKA 3 1
DYRK1A 7 3
DYRK3 8 1
ROCK 2 8 1
MSK1 9 2
PIM3 13 1
PIM1 15 2
PIM2 15 2
PKD1 23 4
HIPK2 24 3
DYRK2 26 1
SmMLCK 27 2
RSK2 27 3
ERK8 28 3
PKC alpha 29 4
MST2 29 0
CDK2-Cyclin A 31 2
S6K1 32 9
RSK1 32 1
GSK3 beta 33 4
SGK1 53 5
PHK 54 6
ERK1 59 3
MELK 63 2
CAMKK beta 63 9
ERK2 64 2
PKC zeta 66 0
MKK1 67 6
AMPK 67 3
p38 delta MAPK 68 9
HIPK3 71 2
MAPKAP-K2 73 0
CK1 delta 74 3
CAMK1 77 6
JNK2 78 9
PDK1 79 8
BRSK2 79 1
PLK1 80 1
Aurora B 80 2
MNK2 80 5
p38 gamma MAPK 83 4
MARK3 83 1
NEK7 84 1
Src 86 5
JNK3 86 8
PAK6 87 3
IKK beta 89 2
CK2 90 8
PAK4 90 6
JNK1 90 3
SRPK1 91 2
p38 alpha MAPK 92 6
Aurora C 92 8
CSK 93 7
EF2K 94 8
NEK2a 95 2
CHK2 95 2
NEK6 95 4
PAK5 96 1
MAPKAP-K3 96 2
Lck 97 3
CHK1 99 2
p38 beta MAPK 105 4
PRAK 107 4
MNK1 109 2
CAMKK alpha 117 1
Screening Concentration: 0.01µM
Kinase % Activity Remainingsort descending Standard Deviation
PKB alpha 5 2
DYRK1A 10 2
PRK2 17 2
PKB beta 17 2
MSK1 19 2
PKA 26 1
DYRK3 41 3
ROCK 2 48 3
PIM3 54 6
PIM1 57 8
PIM2 59 0
ERK8 61 2
PKD1 63 3
SmMLCK 69 2
PKC alpha 73 3
HIPK2 73 2
RSK2 74 3
MST2 76 4
ERK1 77 8
ERK2 78 6
RSK1 78 1
SGK1 78 2
DYRK2 79 5
JNK3 81 9
GSK3 beta 81 1
Aurora B 81 3
PKC zeta 82 3
CDK2-Cyclin A 82 5
CAMKK beta 83 8
AMPK 84 8
MKK1 84 2
PHK 86 7
NEK7 86 8
p38 delta MAPK 86 1
p38 gamma MAPK 87 5
PAK6 87 2
BRSK2 88 9
PDK1 88 1
S6K1 88 3
JNK1 89 7
PLK1 89 5
CAMK1 89 3
HIPK3 90 0
Src 91 0
MAPKAP-K3 91 9
SRPK1 92 8
MAPKAP-K2 92 8
IKK beta 93 8
EF2K 93 7
JNK2 94 1
CHK2 94 8
NEK6 95 2
CK1 delta 95 3
MELK 96 2
CK2 96 0
Lck 97 8
MNK2 97 2
CSK 99 2
PAK4 99 3
CHK1 100 3
Aurora C 100 4
MARK3 100 3
NEK2a 101 5
PAK5 104 2
PRAK 107 3
CAMKK alpha 112 2
p38 beta MAPK 114 3
MNK1 120 3
p38 alpha MAPK 131 2

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