Kinase Profiling Inhibitor Database

Inhibitor Structure Image Brutto MW Action Reference Reference 2 Patent Commercial Vendor Notes Results
1 NM-PP1 (PP1 Analog II) C20H21N5 331.4 Src Ira G. (2004) Nature 431 1011 Papa F.R. (2003) Science 302 1533 WO2000042042 Merck (Calbiochem) Download

Results as Barchart

View results as a bar chart
1µM
10µM

Results as Table

Screening Concentration: 10µM
Kinase % Activity Remaining Standard Deviation
MKK1 76 6
ERK1 45 1
ERK2 32 7
JNK1 85 4
JNK2 63 4
JNK3 79 1
p38 alpha MAPK 8 1
p38 beta MAPK 15 5
p38 gamma MAPK 98 2
p38 delta MAPK 94 4
ERK8 48 0
RSK1 56 6
RSK2 68 2
PDK1 101 0
PKB alpha 62 1
PKB beta 91 4
SGK1 99 5
S6K1 82 6
PKA 7 1
ROCK 2 76 1
PRK2 97 2
PKC alpha 79 2
PKC zeta 84 4
PKD1 3 0
MSK1 69 2
MNK1 105 0
MNK2 98 5
MAPKAP-K2 114 7
MAPKAP-K3 93 1
PRAK 62 1
CAMKK alpha 89 4
CAMKK beta 76 2
CAMK1 46 1
SmMLCK 71 1
PHK 78 3
CHK1 105 0
CHK2 44 3
GSK3 beta 92 3
CDK2-Cyclin A 42 5
PLK1 94 0
Aurora B 82 0
Aurora C 73 1
AMPK 96 2
MARK3 54 2
BRSK2 97 4
MELK 23 0
CK1 delta 14 2
CK2 91 2
DYRK1A 66 2
DYRK2 112 5
DYRK3 58 4
NEK2a 91 5
NEK6 110 1
NEK7 109 8
IKK beta 95 0
PIM1 94 0
PIM2 103 2
PIM3 87 3
SRPK1 93 0
EF2K 105 2
HIPK2 71 3
HIPK3 103 3
PAK4 50 8
PAK5 47 0
PAK6 65 5
MST2 9 0
Src 7 0
Lck 3 0
CSK 6 1
Screening Concentration: 1µM
Kinase % Activity Remaining Standard Deviation
MKK1 112 2
ERK1 84 5
ERK2 64 3
JNK1 90 0
JNK2 78 1
JNK3 98 8
p38 alpha MAPK 41 2
p38 beta MAPK 53 4
p38 gamma MAPK 95 0
p38 delta MAPK 97 1
ERK8 76 0
RSK1 83 2
RSK2 97 1
PDK1 96 1
PKB alpha 82 1
PKB beta 97 4
SGK1 98 1
S6K1 91 7
PKA 32 2
ROCK 2 83 0
PRK2 109 5
PKC alpha 81 1
PKC zeta 82 1
PKD1 13 0
MSK1 78 1
MNK1 109 8
MNK2 114 1
MAPKAP-K2 98 3
MAPKAP-K3 96 1
PRAK 89 0
CAMKK alpha 100 1
CAMKK beta 102 6
CAMK1 83 6
SmMLCK 80 7
PHK 80 5
CHK1 96 7
CHK2 83 2
GSK3 beta 90 3
CDK2-Cyclin A 85 4
PLK1 95 4
Aurora B 105 2
Aurora C 76 1
AMPK 86 2
MARK3 71 6
BRSK2 101 3
MELK 66 2
CK1 delta 56 4
CK2 80 7
DYRK1A 92 8
DYRK2 94 2
DYRK3 80 4
NEK2a 101 6
NEK6 94 3
NEK7 110 2
IKK beta 98 2
PIM1 103 3
PIM2 101 4
PIM3 99 2
SRPK1 99 3
EF2K 99 2
HIPK2 95 4
HIPK3 96 3
PAK4 71 6
PAK5 74 0
PAK6 88 0
MST2 45 2
Src 29 6
Lck 18 2
CSK 36 2

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