Kinase Profiling Inhibitor Database

Inhibitor Structure Image Brutto MW Action Reference Reference 2 Patent Commercial Vendor Notes Results
1 NA-PP1 (PP1 Analog) C19H19N5 317.4 Src Bishop A. C. (2000) Nature 407 395 Bishop A.C. (1999) J. Am. Chem. Soc. 121 627 WO2003082341 Merck (Calbiochem) Download

Results as Barchart

View results as a bar chart
1µM
10µM

Results as Table

Screening Concentration: 1µM
Kinase % Activity Remainingsort ascending Standard Deviation
MAPKAP-K2 116 0
PRK2 110 1
MNK1 109 1
p38 delta MAPK 108 1
BRSK2 108 4
MNK2 105 0
PIM1 104 5
ERK1 103 1
PKB alpha 102 9
HIPK3 101 3
SGK1 101 5
PIM2 100 5
HIPK2 99 2
NEK2a 99 4
PIM3 98 3
NEK6 98 8
EF2K 97 1
PDK1 97 5
CHK1 97 8
p38 gamma MAPK 97 0
RSK2 95 1
PKB beta 95 2
DYRK2 95 1
GSK3 beta 95 1
SRPK1 94 7
CAMKK alpha 94 5
PAK6 94 5
CDK2-Cyclin A 94 3
PLK1 94 2
JNK3 93 3
NEK7 93 6
JNK1 92 4
IKK beta 92 1
DYRK1A 91 4
MAPKAP-K3 90 1
CAMKK beta 90 1
Aurora B 90 7
RSK1 89 2
Aurora C 88 6
PRAK 88 7
CK2 88 0
MKK1 86 5
S6K1 86 6
PKA 86 2
ROCK 2 86 1
PKC zeta 86 0
MELK 84 2
PHK 84 1
DYRK3 84 1
JNK2 84 0
CAMK1 83 3
PAK4 82 2
ERK2 82 4
ERK8 81 1
AMPK 81 6
MSK1 81 6
SmMLCK 78 0
PKC alpha 77 4
p38 beta MAPK 77 1
CHK2 75 3
PAK5 73 9
MARK3 67 2
p38 alpha MAPK 49 1
MST2 46 3
PKD1 35 2
CSK 31 1
CK1 delta 30 0
Lck 30 0
Src 20 6
Screening Concentration: 10µM
Kinase % Activity Remainingsort ascending Standard Deviation
NEK7 106 0
HIPK3 105 0
PIM2 104 0
EF2K 99 2
MAPKAP-K2 97 3
PDK1 97 3
DYRK2 96 7
IKK beta 95 3
PLK1 95 5
MNK1 95 1
CHK1 95 2
NEK2a 95 4
JNK1 93 1
NEK6 91 7
PIM1 91 4
SGK1 91 2
PRK2 89 2
SRPK1 89 7
PKB beta 89 1
JNK3 87 3
MAPKAP-K3 87 5
CK2 87 0
MNK2 85 7
HIPK2 84 1
PKC zeta 83 1
PIM3 83 4
p38 gamma MAPK 81 2
p38 delta MAPK 80 2
GSK3 beta 77 0
DYRK1A 77 8
PRAK 76 0
CAMKK alpha 76 8
BRSK2 75 0
PHK 75 1
Aurora B 74 8
AMPK 73 2
CAMKK beta 72 6
RSK2 71 1
ERK1 69 1
MKK1 65 4
DYRK3 65 1
CAMK1 63 2
ERK2 62 0
S6K1 61 7
SmMLCK 61 4
ERK8 58 4
PAK6 57 6
JNK2 56 4
PKA 56 2
CDK2-Cyclin A 55 1
Aurora C 55 1
RSK1 53 4
PKB alpha 50 0
MSK1 46 6
PKC alpha 39 8
PAK4 35 0
CHK2 32 1
MARK3 30 0
ROCK 2 30 0
MELK 27 0
PAK5 25 3
p38 beta MAPK 24 2
p38 alpha MAPK 17 4
MST2 10 3
PKD1 8 3
Lck 6 1
CSK 5 1
CK1 delta 4 0
Src 3 2

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