Kinase Profiling Inhibitor Database

Inhibitor Structure Image Brutto MW Action Reference Reference 2 Patent Commercial Vendor Notes Results
1 NA-PP1 (PP1 Analog) C19H19N5 317.4 Src Bishop A. C. (2000) Nature 407 395 Bishop A.C. (1999) J. Am. Chem. Soc. 121 627 WO2003082341 Merck (Calbiochem) Download

Results as Barchart

View results as a bar chart
1µM
10µM

Results as Table

Screening Concentration: 10µM
Kinase % Activity Remainingsort descending Standard Deviation
Src 3 2
CK1 delta 4 0
CSK 5 1
Lck 6 1
PKD1 8 3
MST2 10 3
p38 alpha MAPK 17 4
p38 beta MAPK 24 2
PAK5 25 3
MELK 27 0
MARK3 30 0
ROCK 2 30 0
CHK2 32 1
PAK4 35 0
PKC alpha 39 8
MSK1 46 6
PKB alpha 50 0
RSK1 53 4
Aurora C 55 1
CDK2-Cyclin A 55 1
PKA 56 2
JNK2 56 4
PAK6 57 6
ERK8 58 4
S6K1 61 7
SmMLCK 61 4
ERK2 62 0
CAMK1 63 2
MKK1 65 4
DYRK3 65 1
ERK1 69 1
RSK2 71 1
CAMKK beta 72 6
AMPK 73 2
Aurora B 74 8
BRSK2 75 0
PHK 75 1
PRAK 76 0
CAMKK alpha 76 8
DYRK1A 77 8
GSK3 beta 77 0
p38 delta MAPK 80 2
p38 gamma MAPK 81 2
PIM3 83 4
PKC zeta 83 1
HIPK2 84 1
MNK2 85 7
MAPKAP-K3 87 5
CK2 87 0
JNK3 87 3
SRPK1 89 7
PKB beta 89 1
PRK2 89 2
SGK1 91 2
NEK6 91 7
PIM1 91 4
JNK1 93 1
MNK1 95 1
CHK1 95 2
NEK2a 95 4
IKK beta 95 3
PLK1 95 5
DYRK2 96 7
MAPKAP-K2 97 3
PDK1 97 3
EF2K 99 2
PIM2 104 0
HIPK3 105 0
NEK7 106 0
Screening Concentration: 1µM
Kinase % Activity Remainingsort descending Standard Deviation
Src 20 6
CK1 delta 30 0
Lck 30 0
CSK 31 1
PKD1 35 2
MST2 46 3
p38 alpha MAPK 49 1
MARK3 67 2
PAK5 73 9
CHK2 75 3
PKC alpha 77 4
p38 beta MAPK 77 1
SmMLCK 78 0
MSK1 81 6
ERK8 81 1
AMPK 81 6
PAK4 82 2
ERK2 82 4
CAMK1 83 3
MELK 84 2
PHK 84 1
DYRK3 84 1
JNK2 84 0
MKK1 86 5
S6K1 86 6
PKA 86 2
ROCK 2 86 1
PKC zeta 86 0
PRAK 88 7
CK2 88 0
Aurora C 88 6
RSK1 89 2
CAMKK beta 90 1
Aurora B 90 7
MAPKAP-K3 90 1
DYRK1A 91 4
JNK1 92 4
IKK beta 92 1
JNK3 93 3
NEK7 93 6
CAMKK alpha 94 5
PAK6 94 5
CDK2-Cyclin A 94 3
PLK1 94 2
SRPK1 94 7
PKB beta 95 2
DYRK2 95 1
GSK3 beta 95 1
RSK2 95 1
PDK1 97 5
CHK1 97 8
p38 gamma MAPK 97 0
EF2K 97 1
NEK6 98 8
PIM3 98 3
HIPK2 99 2
NEK2a 99 4
PIM2 100 5
HIPK3 101 3
SGK1 101 5
PKB alpha 102 9
ERK1 103 1
PIM1 104 5
MNK2 105 0
p38 delta MAPK 108 1
BRSK2 108 4
MNK1 109 1
PRK2 110 1
MAPKAP-K2 116 0

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