Kinase Profiling Inhibitor Database

Inhibitor Structure Image Brutto MW Action Reference Reference 2 Patent Commercial Vendor Notes Results
1 NA-PP1 (PP1 Analog) C19H19N5 317.4 Src Bishop A. C. (2000) Nature 407 395 Bishop A.C. (1999) J. Am. Chem. Soc. 121 627 WO2003082341 Merck (Calbiochem) Download

Results as Barchart

View results as a bar chart
1µM
10µM

Results as Table

Screening Concentration: 1µM
Kinase % Activity Remaining Standard Deviation
MKK1 86 5
ERK1 103 1
ERK2 82 4
JNK1 92 4
JNK2 84 0
JNK3 93 3
p38 alpha MAPK 49 1
p38 beta MAPK 77 1
p38 gamma MAPK 97 0
p38 delta MAPK 108 1
ERK8 81 1
RSK1 89 2
RSK2 95 1
PDK1 97 5
PKB alpha 102 9
PKB beta 95 2
SGK1 101 5
S6K1 86 6
PKA 86 2
ROCK 2 86 1
PRK2 110 1
PKC alpha 77 4
PKC zeta 86 0
PKD1 35 2
MSK1 81 6
MNK1 109 1
MNK2 105 0
MAPKAP-K2 116 0
MAPKAP-K3 90 1
PRAK 88 7
CAMKK alpha 94 5
CAMKK beta 90 1
CAMK1 83 3
SmMLCK 78 0
PHK 84 1
CHK1 97 8
CHK2 75 3
GSK3 beta 95 1
CDK2-Cyclin A 94 3
PLK1 94 2
Aurora B 90 7
Aurora C 88 6
AMPK 81 6
MARK3 67 2
BRSK2 108 4
MELK 84 2
CK1 delta 30 0
CK2 88 0
DYRK1A 91 4
DYRK2 95 1
DYRK3 84 1
NEK2a 99 4
NEK6 98 8
NEK7 93 6
IKK beta 92 1
PIM1 104 5
PIM2 100 5
PIM3 98 3
SRPK1 94 7
EF2K 97 1
HIPK2 99 2
HIPK3 101 3
PAK4 82 2
PAK5 73 9
PAK6 94 5
MST2 46 3
Src 20 6
Lck 30 0
CSK 31 1
Screening Concentration: 10µM
Kinase % Activity Remaining Standard Deviation
MKK1 65 4
ERK1 69 1
ERK2 62 0
JNK1 93 1
JNK2 56 4
JNK3 87 3
p38 alpha MAPK 17 4
p38 beta MAPK 24 2
p38 gamma MAPK 81 2
p38 delta MAPK 80 2
ERK8 58 4
RSK1 53 4
RSK2 71 1
PDK1 97 3
PKB alpha 50 0
PKB beta 89 1
SGK1 91 2
S6K1 61 7
PKA 56 2
ROCK 2 30 0
PRK2 89 2
PKC alpha 39 8
PKC zeta 83 1
PKD1 8 3
MSK1 46 6
MNK1 95 1
MNK2 85 7
MAPKAP-K2 97 3
MAPKAP-K3 87 5
PRAK 76 0
CAMKK alpha 76 8
CAMKK beta 72 6
CAMK1 63 2
SmMLCK 61 4
PHK 75 1
CHK1 95 2
CHK2 32 1
GSK3 beta 77 0
CDK2-Cyclin A 55 1
PLK1 95 5
Aurora B 74 8
Aurora C 55 1
AMPK 73 2
MARK3 30 0
BRSK2 75 0
MELK 27 0
CK1 delta 4 0
CK2 87 0
DYRK1A 77 8
DYRK2 96 7
DYRK3 65 1
NEK2a 95 4
NEK6 91 7
NEK7 106 0
IKK beta 95 3
PIM1 91 4
PIM2 104 0
PIM3 83 4
SRPK1 89 7
EF2K 99 2
HIPK2 84 1
HIPK3 105 0
PAK4 35 0
PAK5 25 3
PAK6 57 6
MST2 10 3
Src 3 2
Lck 6 1
CSK 5 1

Do you need any help? Please get in touch and we’ll be happy to lend a hand.