Kinase Profiling Inhibitor Database

Inhibitor Structure Image Brutto MW Action Reference Reference 2 Patent Commercial Vendor Notes Results
CCT250862 NEK Download

Results as Barchart

View results as a bar chart
1µM

Results as Table

Screening Concentration: 1µM
Kinase % Activity Remaining Standard Deviation
MKK1 84 3
MKK2 91 3
MKK6 82 7
ERK1 78 3
ERK2 74 6
ERK5 36 7
JNK1 76 2
JNK2 70 3
JNK3 86 10
p38 alpha MAPK 108 24
p38 beta MAPK 86 5
p38 gamma MAPK 90 6
p38 delta MAPK 80 0
ERK8 15 7
RSK1 42 16
RSK2 62 1
PDK1 74 10
PKB alpha 89 2
PKB beta 95 25
SGK1 54 2
S6K1 21 2
PKA 86 4
ROCK 2 89 10
PRK2 17 1
PKC alpha 32 3
PKC gamma 36 6
PKC zeta 68 9
PKD1 31 2
STK33 25 2
MSK1 29 5
MNK1 37 8
MNK2 25 2
MAPKAP-K2 91 3
MAPKAP-K3 99 0
PRAK 89 5
CAMKK beta 38 44
CAMK1 105 2
SmMLCK 18 2
PHK 24 0
DAPK1 81 6
CHK1 85 3
CHK2 51 5
GSK3 beta 5 1
CDK2-Cyclin A 41 7
CDK9-Cyclin T1 54 9
PLK1 81 17
Aurora A 113 5
Aurora B 54 16
TLK1 96 3
LKB1 46 3
AMPK 24 4
AMPK (hum) 15 2
MARK1 46 3
MARK2 34 3
MARK3 26 1
MARK4 45 7
BRSK1 23 6
BRSK2 21 2
MELK 27 5
NUAK1 2 1
SIK2 14 5
SIK3 56 0
TSSK1 51 1
CK1 gamma 2 39 5
CK1 delta 9 1
CK2 96 8
TTBK1 98 12
TTBK2 94 3
DYRK1A 4 0
DYRK2 92 6
DYRK3 38 2
NEK2a 55 15
NEK6 106 3
IKK beta 91 4
IKK epsilon 32 3
TBK1 42 10
PIM1 48 5
PIM2 95 2
PIM3 51 3
SRPK1 78 3
EF2K 85 4
EIF2AK3 100 2
HIPK1 30 12
HIPK2 23 6
HIPK3 65 14
CLK2 2 0
PAK2 87 6
PAK4 84 1
PAK5 97 10
PAK6 95 3
MST2 23 11
MST3 60 2
MST4 41 11
GCK 3 0
MAP4K3 6 2
MAP4K5 7 1
MINK1 6 1
MEKK1 85 2
MLK1 17 7
MLK3 4 1
TESK1 76 11
TAO1 25 0
ASK1 73 11
TAK1 6 0
IRAK1 11 3
IRAK4 33 7
RIPK2 11 2
OSR1 68 5
TTK 62 1
MPSK1 100 1
WNK1 108 8
ULK1 67 8
ULK2 37 3
TGFBR1 42 1
Src 13 1
Lck 9 1
CSK 55 2
YES1 6 1
ABL 17 1
BTK 37 3
JAK2 27 0
SYK 94 1
ZAP70 95 14
TIE2 41 1
BRK 68 4
EPH-A2 69 2
EPH-A4 64 13
EPH-B1 114 10
EPH-B2 40 5
EPH-B3 91 14
EPH-B4 94 11
FGF-R1 17 1
HER4 93 4
IGF-1R 17 7
IR 64 8
IRR 16 2
TrkA 10 1
DDR2 28 2
VEGFR1 6 0
PDGFRA 70 11

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