Kinase Profiling Inhibitor Database

Inhibitor Structure Image Brutto MW Action Reference Reference 2 Patent Commercial Vendor Notes Results
HG-10-102-01 LRRK2 Choi H.G. (2012) ACS Med. Chem. Lett. Download

Results as Barchart

View results as a bar chart
1µM
10µM

Results as Table

Screening Concentration: 10µM
Kinase % Activity Remainingsort descending Standard Deviation
MNK2 7 2
MLK1 18 0
TSSK1 19 1
NUAK1 20 6
DYRK2 21 6
DAPK1 23 5
PHK 23 4
TAK1 25 8
PKD1 25 4
STK33 28 1
JNK3 29 10
CAMKK beta 31 3
VEGFR1 35 2
JNK1 37 2
BRK 39 1
TBK1 42 1
Aurora B 42 4
MLK3 43 9
MNK1 44 6
PRAK 44 1
CHK1 45 4
Aurora A 45 9
JNK2 46 3
SIK2 47 0
IR 50 7
IGF-1R 51 7
RSK1 54 2
ASK1 54 3
SmMLCK 55 3
PDGFRA 56 1
TTK 57 5
BRSK2 64 5
PKB beta 64 8
CDK2-Cyclin A 65 4
RSK2 65 10
MKK6 65 7
CAMK1 66 3
S6K1 67 15
NEK6 69 19
ERK2 69 11
MAP4K3 70 9
AMPK (hum) 71 6
ROCK 2 71 2
MARK4 72 6
PIM3 72 4
MST2 73 10
IKK epsilon 75 2
CLK2 76 5
DYRK3 76 3
BRSK1 78 0
MARK3 78 2
GCK 79 11
Src 79 0
JAK2 80 18
PAK5 80 0
IKK beta 80 7
RIPK2 80 2
MST3 80 5
AMPK 80 1
DYRK1A 80 2
HIPK3 80 5
ZAP70 81 7
MAPKAP-K3 81 2
OSR1 82 10
ERK8 82 5
SIK3 82 3
MAP4K5 82 7
IRAK1 83 11
CDK9-Cyclin T1 83 3
TESK1 83 15
PAK4 84 8
MSK1 84 11
ULK2 84 6
MARK1 84 7
SYK 85 9
ULK1 85 2
PKB alpha 85 1
IRAK4 86 3
p38 delta MAPK 86 3
EPH-B1 86 5
EF2K 86 9
MKK2 86 10
FGF-R1 86 10
ABL 86 9
TrkA 87 1
PKC alpha 87 9
CK2 88 1
HIPK2 88 6
BTK 88 2
PDK1 89 8
CK1 delta 89 9
NEK2a 90 13
DDR2 90 16
TIE2 90 0
LKB1 90 8
YES1 90 5
MARK2 90 6
TTBK1 91 4
SGK1 91 1
PRK2 92 10
p38 alpha MAPK 93 10
p38 beta MAPK 93 6
CK1 gamma 2 93 2
MKK1 93 7
TAO1 93 4
p38 gamma MAPK 94 11
EPH-A4 94 7
SRPK1 94 22
HIPK1 94 7
HER4 94 2
PKA 94 8
Lck 95 5
CHK2 96 15
MINK1 96 14
EPH-A2 97 4
PIM2 97 13
MPSK1 97 7
EIF2AK3 97 2
TTBK2 97 12
IRR 97 9
PAK6 98 9
GSK3 beta 98 6
MELK 98 3
MEKK1 98 7
PIM1 99 0
WNK1 99 6
TLK1 100 9
PKC zeta 101 9
EPH-B3 101 17
MAPKAP-K2 102 2
EPH-B2 103 8
CSK 103 11
ERK1 104 22
PLK1 105 4
PAK2 105 4
MST4 106 9
PKC gamma 108 6
EPH-B4 113 7
Screening Concentration: 1µM
Kinase % Activity Remainingsort descending Standard Deviation
MNK2 20 9
MLK1 38 3
NUAK1 43 1
DYRK2 44 7
CK1 delta 44 7
SIK2 49 11
CK2 50 8
TSSK1 51 3
CAMKK beta 52 13
CHK2 52 2
PKB alpha 53 1
BRK 56 2
Aurora A 56 4
p38 beta MAPK 57 11
BRSK1 59 18
JNK3 60 1
DAPK1 61 13
STK33 61 1
TLK1 61 7
WNK1 62 20
ULK1 62 10
NEK2a 63 1
CHK1 65 29
VEGFR1 65 25
PKC alpha 66 6
EPH-B3 67 2
PHK 68 11
SYK 68 17
S6K1 70 15
ASK1 70 3
PKD1 70 5
p38 alpha MAPK 71 8
TTK 71 0
MNK1 71 11
NEK6 73 25
MKK6 74 29
TAK1 74 16
ERK8 74 26
MLK3 75 10
JNK2 76 10
HIPK1 77 10
HIPK2 77 23
IKK epsilon 77 31
PIM3 77 0
BRSK2 78 11
DYRK1A 79 12
ERK2 79 5
RIPK2 79 6
TIE2 79 3
PDGFRA 79 0
YES1 80 3
TrkA 80 14
TAO1 81 22
MARK4 82 7
IKK beta 82 2
CDK2-Cyclin A 82 2
SmMLCK 83 1
BTK 83 8
JAK2 83 8
MST3 83 9
Aurora B 83 1
MAP4K5 83 7
EF2K 83 3
Src 84 6
ABL 84 7
DYRK3 84 1
IRAK1 84 21
CAMK1 85 1
HIPK3 85 0
PKA 85 10
MARK2 85 7
MST2 85 17
IR 86 4
TBK1 86 3
MINK1 86 4
ROCK 2 87 7
PAK4 87 1
p38 delta MAPK 87 0
RSK1 87 10
TTBK1 88 8
PAK5 88 3
MELK 88 21
p38 gamma MAPK 88 21
MAPKAP-K2 88 4
AMPK 89 5
FGF-R1 89 6
HER4 89 4
JNK1 89 8
CDK9-Cyclin T1 89 7
TESK1 90 0
PAK6 90 8
IRAK4 90 6
MKK2 91 17
PRAK 91 0
AMPK (hum) 91 7
MARK1 91 9
CLK2 91 1
MARK3 91 1
LKB1 92 1
Lck 92 4
RSK2 92 7
MEKK1 93 2
PKC gamma 93 2
EPH-A2 93 9
SIK3 93 6
EPH-B4 94 12
SGK1 94 3
PIM2 94 13
MAP4K3 94 11
PKB beta 95 11
ERK1 95 16
PIM1 96 8
CK1 gamma 2 96 10
SRPK1 96 1
CSK 97 1
PAK2 97 4
ZAP70 97 4
PLK1 97 23
ULK2 97 9
EIF2AK3 99 19
PKC zeta 99 10
IGF-1R 100 3
GSK3 beta 100 1
MPSK1 100 2
EPH-A4 100 4
MST4 101 1
PRK2 102 12
PDK1 102 11
DDR2 103 16
MSK1 104 8
EPH-B2 105 7
MKK1 106 15
OSR1 108 1
GCK 108 10
TTBK2 115 11
EPH-B1 115 1
MAPKAP-K3 120 81
IRR 126 5

Do you need any help? Please get in touch and we’ll be happy to lend a hand.