Kinase Profiling Inhibitor Database

Inhibitor Structure Image Brutto MW Action Reference Reference 2 Patent Commercial Vendor Notes Results
HG-10-102-01 LRRK2 Choi H.G. (2012) ACS Med. Chem. Lett. Download

Results as Barchart

View results as a bar chart
1µM
10µM

Results as Table

Screening Concentration: 10µM
Kinase % Activity Remainingsort descending Standard Deviation
MNK2 7 2
MLK1 18 0
TSSK1 19 1
NUAK1 20 6
DYRK2 21 6
PHK 23 4
DAPK1 23 5
TAK1 25 8
PKD1 25 4
STK33 28 1
JNK3 29 10
CAMKK beta 31 3
VEGFR1 35 2
JNK1 37 2
BRK 39 1
TBK1 42 1
Aurora B 42 4
MLK3 43 9
PRAK 44 1
MNK1 44 6
CHK1 45 4
Aurora A 45 9
JNK2 46 3
SIK2 47 0
IR 50 7
IGF-1R 51 7
ASK1 54 3
RSK1 54 2
SmMLCK 55 3
PDGFRA 56 1
TTK 57 5
PKB beta 64 8
BRSK2 64 5
MKK6 65 7
CDK2-Cyclin A 65 4
RSK2 65 10
CAMK1 66 3
S6K1 67 15
ERK2 69 11
NEK6 69 19
MAP4K3 70 9
AMPK (hum) 71 6
ROCK 2 71 2
MARK4 72 6
PIM3 72 4
MST2 73 10
IKK epsilon 75 2
CLK2 76 5
DYRK3 76 3
MARK3 78 2
BRSK1 78 0
Src 79 0
GCK 79 11
AMPK 80 1
DYRK1A 80 2
HIPK3 80 5
JAK2 80 18
PAK5 80 0
IKK beta 80 7
RIPK2 80 2
MST3 80 5
MAPKAP-K3 81 2
ZAP70 81 7
OSR1 82 10
ERK8 82 5
SIK3 82 3
MAP4K5 82 7
TESK1 83 15
IRAK1 83 11
CDK9-Cyclin T1 83 3
ULK2 84 6
MARK1 84 7
PAK4 84 8
MSK1 84 11
PKB alpha 85 1
SYK 85 9
ULK1 85 2
EF2K 86 9
MKK2 86 10
FGF-R1 86 10
ABL 86 9
IRAK4 86 3
p38 delta MAPK 86 3
EPH-B1 86 5
TrkA 87 1
PKC alpha 87 9
CK2 88 1
HIPK2 88 6
BTK 88 2
PDK1 89 8
CK1 delta 89 9
LKB1 90 8
YES1 90 5
MARK2 90 6
NEK2a 90 13
DDR2 90 16
TIE2 90 0
TTBK1 91 4
SGK1 91 1
PRK2 92 10
MKK1 93 7
TAO1 93 4
p38 alpha MAPK 93 10
p38 beta MAPK 93 6
CK1 gamma 2 93 2
HIPK1 94 7
HER4 94 2
PKA 94 8
p38 gamma MAPK 94 11
EPH-A4 94 7
SRPK1 94 22
Lck 95 5
MINK1 96 14
CHK2 96 15
EIF2AK3 97 2
TTBK2 97 12
IRR 97 9
EPH-A2 97 4
PIM2 97 13
MPSK1 97 7
MEKK1 98 7
PAK6 98 9
GSK3 beta 98 6
MELK 98 3
PIM1 99 0
WNK1 99 6
TLK1 100 9
EPH-B3 101 17
PKC zeta 101 9
MAPKAP-K2 102 2
CSK 103 11
EPH-B2 103 8
ERK1 104 22
PAK2 105 4
PLK1 105 4
MST4 106 9
PKC gamma 108 6
EPH-B4 113 7
Screening Concentration: 1µM
Kinase % Activity Remainingsort descending Standard Deviation
MNK2 20 9
MLK1 38 3
NUAK1 43 1
CK1 delta 44 7
DYRK2 44 7
SIK2 49 11
CK2 50 8
TSSK1 51 3
CAMKK beta 52 13
CHK2 52 2
PKB alpha 53 1
BRK 56 2
Aurora A 56 4
p38 beta MAPK 57 11
BRSK1 59 18
JNK3 60 1
STK33 61 1
TLK1 61 7
DAPK1 61 13
WNK1 62 20
ULK1 62 10
NEK2a 63 1
CHK1 65 29
VEGFR1 65 25
PKC alpha 66 6
EPH-B3 67 2
PHK 68 11
SYK 68 17
PKD1 70 5
S6K1 70 15
ASK1 70 3
TTK 71 0
MNK1 71 11
p38 alpha MAPK 71 8
NEK6 73 25
ERK8 74 26
MKK6 74 29
TAK1 74 16
MLK3 75 10
JNK2 76 10
IKK epsilon 77 31
PIM3 77 0
HIPK1 77 10
HIPK2 77 23
BRSK2 78 11
RIPK2 79 6
TIE2 79 3
PDGFRA 79 0
DYRK1A 79 12
ERK2 79 5
YES1 80 3
TrkA 80 14
TAO1 81 22
CDK2-Cyclin A 82 2
MARK4 82 7
IKK beta 82 2
MST3 83 9
Aurora B 83 1
MAP4K5 83 7
EF2K 83 3
SmMLCK 83 1
BTK 83 8
JAK2 83 8
Src 84 6
ABL 84 7
DYRK3 84 1
IRAK1 84 21
MST2 85 17
CAMK1 85 1
HIPK3 85 0
PKA 85 10
MARK2 85 7
TBK1 86 3
MINK1 86 4
IR 86 4
p38 delta MAPK 87 0
RSK1 87 10
ROCK 2 87 7
PAK4 87 1
MELK 88 21
p38 gamma MAPK 88 21
MAPKAP-K2 88 4
TTBK1 88 8
PAK5 88 3
CDK9-Cyclin T1 89 7
AMPK 89 5
FGF-R1 89 6
HER4 89 4
JNK1 89 8
TESK1 90 0
PAK6 90 8
IRAK4 90 6
MKK2 91 17
PRAK 91 0
AMPK (hum) 91 7
MARK1 91 9
CLK2 91 1
MARK3 91 1
RSK2 92 7
LKB1 92 1
Lck 92 4
EPH-A2 93 9
SIK3 93 6
MEKK1 93 2
PKC gamma 93 2
PIM2 94 13
MAP4K3 94 11
EPH-B4 94 12
SGK1 94 3
PKB beta 95 11
ERK1 95 16
PIM1 96 8
CK1 gamma 2 96 10
SRPK1 96 1
PLK1 97 23
ULK2 97 9
CSK 97 1
PAK2 97 4
ZAP70 97 4
PKC zeta 99 10
EIF2AK3 99 19
GSK3 beta 100 1
MPSK1 100 2
EPH-A4 100 4
IGF-1R 100 3
MST4 101 1
PDK1 102 11
PRK2 102 12
DDR2 103 16
MSK1 104 8
EPH-B2 105 7
MKK1 106 15
OSR1 108 1
GCK 108 10
EPH-B1 115 1
TTBK2 115 11
MAPKAP-K3 120 81
IRR 126 5

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