Kinase Profiling Inhibitor Database

Inhibitor Structure Image Brutto MW Action Reference Reference 2 Patent Commercial Vendor Notes Results
IRAK-4 kinase inhibitor b C22H24N4O6 440.45 IRAK4 Download

Results as Barchart

View results as a bar chart
1µM
0.1µM

Results as Table

Screening Concentration: 1µM
Kinase % Activity Remainingsort descending Standard Deviation
IRAK1 8 3
IRAK4 8 2
CLK2 16 3
TAK1 34 5
CK1 delta 40 1
MINK1 46 1
SRPK1 58 6
MKK2 59 5
CAMKK beta 61 1
GCK 61 3
IRR 61 3
ERK8 63 0
DYRK1A 64 3
PHK 65 9
TTK 66 1
MLK1 66 2
VEGFR1 66 22
PKD1 70 4
DYRK3 71 1
NEK6 71 0
TrkA 73 1
CK2 74 7
PKB beta 74 12
HIPK2 76 12
PAK5 76 1
STK33 77 6
Aurora B 77 2
PAK4 77 5
NUAK1 78 2
p38 alpha MAPK 80 7
SGK1 81 17
LKB1 82 2
MKK1 82 1
MARK1 82 1
ERK1 83 2
GSK3 beta 83 4
CDK2-Cyclin A 83 6
RSK1 83 4
MARK2 84 0
MLK3 84 12
HIPK1 84 10
HIPK3 84 10
MAPKAP-K3 84 2
MARK3 85 7
IKK epsilon 85 7
Lck 85 1
JAK2 85 2
CHK2 86 1
Aurora A 86 3
TTBK1 86 7
EPH-A2 86 4
NEK2a 86 3
IKK beta 87 3
PIM1 87 3
IGF-1R 87 14
EF2K 87 3
p38 delta MAPK 87 9
EPH-B3 88 4
PIM2 88 2
CSK 88 0
p38 gamma MAPK 88 14
SmMLCK 89 13
MARK4 89 2
DAPK1 89 3
CHK1 89 2
MELK 89 4
TSSK1 89 8
RSK2 89 18
PAK2 89 6
PIM3 90 5
ASK1 90 5
MPSK1 91 8
PRK2 91 7
TBK1 92 2
Src 92 14
EPH-B4 92 1
TESK1 92 6
AMPK 92 8
ERK2 93 1
PKA 93 2
JNK2 93 5
p38 beta MAPK 93 4
MSK1 93 7
TIE2 93 15
PKB alpha 93 3
PRAK 93 7
PAK6 94 9
S6K1 94 2
MST4 94 0
PKC gamma 94 5
RIPK2 94 2
MST2 95 2
JNK3 95 13
TLK1 95 7
DYRK2 95 1
OSR1 95 1
ROCK 2 96 5
HER4 96 1
MEKK1 96 4
MNK2 96 6
EPH-A4 96 4
EPH-B2 97 7
YES1 97 2
IR 97 6
ZAP70 98 23
PLK1 99 5
PDK1 99 3
EPH-B1 99 15
JNK1 100 24
BRSK2 100 8
TAO1 100 10
PKC alpha 101 1
ABL 101 10
EIF2AK3 101 5
SYK 101 9
BRK 102 8
BTK 103 6
MAPKAP-K2 103 4
MNK1 104 0
FGF-R1 105 2
BRSK1 107 6
PKC zeta 108 2
CAMK1 122 15
MKK6 124 17
Screening Concentration: 0.1µM
Kinase % Activity Remainingsort descending Standard Deviation
IRAK1 18 4
IRAK4 34 4
CLK2 70 16
Aurora B 71 9
TrkA 73 12
CSK 74 6
TAK1 76 27
CK1 delta 79 5
CK2 81 0
PAK4 81 14
PKB beta 82 8
NEK6 82 10
p38 alpha MAPK 83 10
p38 delta MAPK 83 15
ERK8 83 14
HIPK3 83 12
TIE2 83 4
RIPK2 83 24
CHK1 84 4
RSK1 84 12
MARK4 85 9
EPH-B4 85 14
Lck 85 18
MLK1 86 11
MKK2 86 6
BTK 87 1
EIF2AK3 87 10
SYK 87 12
MINK1 88 9
PKD1 88 6
HIPK2 88 5
CAMKK beta 88 13
SmMLCK 88 14
PIM2 89 5
HER4 89 20
EF2K 89 21
JAK2 89 2
TTK 89 18
TBK1 89 12
DAPK1 90 11
NUAK1 90 12
VEGFR1 90 1
IKK epsilon 90 2
MPSK1 90 1
GSK3 beta 91 13
ERK1 91 11
MST4 91 4
GCK 91 7
RSK2 92 14
LKB1 92 12
MARK3 92 11
SRPK1 93 3
IR 93 22
p38 beta MAPK 93 13
CDK2-Cyclin A 93 2
STK33 93 28
TTBK1 93 1
PAK2 93 13
MAPKAP-K3 93 21
IKK beta 93 9
PKA 93 9
BRSK2 94 5
DYRK1A 94 3
EPH-A2 94 14
MKK1 94 7
AMPK 94 2
NEK2a 94 6
EPH-A4 94 8
PIM3 95 2
PLK1 95 9
MARK1 95 13
SGK1 95 1
ROCK 2 95 15
PHK 95 6
JNK2 96 11
IGF-1R 96 24
CHK2 96 17
Aurora A 96 4
MNK2 96 2
BRK 96 6
PIM1 96 8
JNK3 97 9
MLK3 97 8
JNK1 97 13
BRSK1 97 24
p38 gamma MAPK 98 11
MSK1 98 1
DYRK3 98 2
PKB alpha 98 7
S6K1 98 2
EPH-B3 98 11
MELK 99 21
PKC gamma 99 1
PKC zeta 99 14
ZAP70 99 11
PAK5 99 13
PDK1 100 9
TESK1 101 7
MAPKAP-K2 101 1
OSR1 101 2
PAK6 101 16
TSSK1 102 20
IRR 102 19
TAO1 102 11
DYRK2 102 13
PRK2 103 23
PRAK 103 12
MST2 103 11
ERK2 103 12
ASK1 104 3
TLK1 104 12
EPH-B2 104 16
ABL 105 20
MEKK1 106 27
YES1 106 4
HIPK1 106 15
MARK2 106 16
FGF-R1 106 4
MNK1 107 10
EPH-B1 107 29
PKC alpha 108 9
MKK6 108 4
Src 111 15
CAMK1 120 10

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