Kinase Profiling Inhibitor Database

Inhibitor Structure Image Brutto MW Action Reference Reference 2 Patent Commercial Vendor Notes Results
JNKIN8 C29H29N7O2 507.59 JNK Zhang T. (2012) Chem Biol. 19(1) 140-54 Download

Results as Barchart

View results as a bar chart
1µM
0.1µM

Results as Table

Screening Concentration: 1µM
Kinase % Activity Remainingsort descending Standard Deviation
JNK1 6 2
JNK3 13 4
JNK2 17 3
YES1 39 9
NUAK1 49 7
RIPK2 49 8
Src 50 7
VEGFR1 53 7
CK1 delta 57 0
MELK 63 0
CAMKK beta 63 11
IRAK1 63 5
ERK8 64 9
TTK 65 11
TAK1 66 6
ULK1 67 0
MNK2 67 13
ULK2 69 5
CHK2 72 10
DYRK2 72 8
MST2 72 12
GCK 73 0
IKK beta 74 1
BRK 75 8
RSK2 76 7
CK2 77 4
AMPK 77 8
BRSK2 77 13
MINK1 78 7
PAK4 78 7
MST4 79 3
SIK3 79 2
EPH-A4 80 10
p38 delta MAPK 80 12
CDK9-Cyclin T1 80 4
MSK1 80 0
IR 80 9
BTK 80 12
DYRK3 80 4
ROCK 2 80 1
RSK1 81 7
MST3 82 2
MEKK1 82 3
FGF-R1 82 12
PRAK 82 4
PAK5 82 7
PIM3 83 10
TTBK1 83 10
SRPK1 84 10
DYRK1A 84 3
MARK4 84 5
PDK1 85 6
MARK2 85 7
TSSK1 86 9
Aurora B 86 9
ABL 86 7
CAMK1 86 7
IRAK4 86 0
PHK 86 5
CK1 gamma 2 87 8
HIPK1 87 9
IGF-1R 87 5
NEK6 87 2
BRSK1 87 11
CHK1 87 13
p38 beta MAPK 88 8
MNK1 88 12
MLK1 88 1
IRR 88 22
CLK2 88 19
SYK 88 19
PKC zeta 89 7
PIM1 89 8
PKD1 89 1
GSK3 beta 90 6
STK33 90 6
MAPKAP-K3 90 8
HIPK3 90 5
PAK2 90 3
DAPK1 90 3
PKC alpha 90 9
PKC gamma 91 8
Aurora A 91 6
PKB beta 91 7
ASK1 91 13
OSR1 91 10
CDK2-Cyclin A 92 8
Lck 92 10
MKK2 92 3
TrkA 92 2
EIF2AK3 93 11
CSK 93 1
TESK1 93 8
S6K1 93 1
PKA 93 6
MARK3 93 2
PLK1 94 13
MLK3 94 13
JAK2 94 5
IKK epsilon 94 17
EPH-B1 95 1
p38 gamma MAPK 95 2
EF2K 95 4
LKB1 95 12
MKK6 95 4
ZAP70 95 20
PRK2 95 4
MKK1 96 10
SmMLCK 96 2
PAK6 96 1
EPH-B2 97 11
TAO1 97 18
DDR2 97 9
EPH-B4 98 15
HER4 98 15
PKB alpha 98 5
TIE2 98 14
PIM2 99 9
HIPK2 99 14
ERK1 99 2
MAPKAP-K2 100 4
TLK1 100 2
ERK2 100 6
NEK2a 100 16
MPSK1 101 17
SGK1 102 28
SIK2 105 14
EPH-B3 105 18
MARK1 105 20
TBK1 106 2
WNK1 107 15
p38 alpha MAPK 110 2
EPH-A2 111 17
Screening Concentration: 0.1µM
Kinase % Activity Remainingsort descending Standard Deviation
JNK1 13 2
JNK3 14 1
ULK1 27 2
ULK2 28 4
IKK beta 62 5
DYRK2 73 0
NUAK1 79 10
RIPK2 82 4
RSK2 82 2
MNK2 84 6
PDK1 84 8
PHK 85 19
TTK 85 3
MST3 85 3
CDK9-Cyclin T1 85 18
Src 85 8
ROCK 2 86 12
MNK1 86 27
JNK2 87 21
BRSK2 87 7
EPH-A4 87 4
Aurora B 87 2
YES1 87 13
IRAK4 88 24
SIK3 88 1
RSK1 89 5
CK1 delta 89 13
TESK1 89 10
p38 beta MAPK 90 7
ERK8 90 4
TAK1 90 5
MELK 91 3
MSK1 91 11
TSSK1 91 7
MAPKAP-K3 91 25
CAMK1 92 1
MARK3 92 5
IKK epsilon 92 8
PKC gamma 92 6
TTBK1 92 2
HIPK2 92 10
PRAK 92 10
IRAK1 93 18
PKC alpha 93 5
CK2 93 4
IRR 93 1
DYRK3 94 6
BRK 94 42
MINK1 94 6
NEK6 95 18
MEKK1 95 17
MLK3 95 0
OSR1 96 0
MST4 96 0
p38 delta MAPK 96 10
Lck 96 0
BTK 96 5
SmMLCK 97 0
EPH-B1 97 4
SRPK1 97 1
EPH-B4 97 3
Aurora A 97 2
ABL 97 3
HIPK3 97 3
S6K1 98 4
PAK4 98 21
GCK 98 9
PLK1 98 7
EF2K 98 6
MLK1 98 7
MKK2 98 19
DYRK1A 98 0
MARK2 99 4
PAK2 99 9
BRSK1 99 8
p38 gamma MAPK 99 6
PKD1 99 15
STK33 99 16
TLK1 99 5
PKB beta 99 11
VEGFR1 100 2
PAK5 100 7
MST2 100 23
TBK1 100 20
SIK2 100 3
ASK1 100 13
MKK6 100 12
JAK2 100 2
MARK4 101 16
EPH-B2 101 11
AMPK 101 12
DAPK1 102 7
CHK1 102 19
CHK2 102 10
WNK1 102 3
HER4 102 5
MAPKAP-K2 102 6
PKB alpha 102 6
IR 102 9
CLK2 102 14
TrkA 102 30
ERK1 103 1
SYK 103 10
PIM3 103 26
FGF-R1 103 6
EIF2AK3 103 6
HIPK1 103 19
PIM1 104 6
PIM2 104 9
PKA 105 14
NEK2a 105 9
ZAP70 105 10
TIE2 105 1
p38 alpha MAPK 105 2
DDR2 106 5
IGF-1R 106 37
LKB1 106 6
CDK2-Cyclin A 107 4
MKK1 107 6
CK1 gamma 2 109 6
ERK2 110 15
PAK6 110 11
MPSK1 110 8
CSK 110 16
PRK2 112 9
EPH-B3 112 20
GSK3 beta 114 2
MARK1 114 7
PKC zeta 116 3
SGK1 117 20
EPH-A2 118 13
TAO1 124 5
CAMKK beta 133 24

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