Kinase Profiling Inhibitor Database

Inhibitor Structure Image Brutto MW Action Reference Reference 2 Patent Commercial Vendor Notes Results
JNKIN8 C29H29N7O2 507.59 JNK Zhang T. (2012) Chem Biol. 19(1) 140-54 Download

Results as Barchart

View results as a bar chart
1µM
0.1µM

Results as Table

Screening Concentration: 1µM
Kinase % Activity Remaining Standard Deviation
MKK1 96 10
MKK2 92 3
MKK6 95 4
ERK1 99 2
ERK2 100 6
JNK1 6 2
JNK2 17 3
JNK3 13 4
p38 alpha MAPK 110 2
p38 beta MAPK 88 8
p38 gamma MAPK 95 2
p38 delta MAPK 80 12
ERK8 64 9
RSK1 81 7
RSK2 76 7
PDK1 85 6
PKB alpha 98 5
PKB beta 91 7
SGK1 102 28
S6K1 93 1
PKA 93 6
ROCK 2 80 1
PRK2 95 4
PKC alpha 90 9
PKC gamma 91 8
PKC zeta 89 7
PKD1 89 1
STK33 90 6
MSK1 80 0
MNK1 88 12
MNK2 67 13
MAPKAP-K2 100 4
MAPKAP-K3 90 8
PRAK 82 4
CAMKK beta 63 11
CAMK1 86 7
SmMLCK 96 2
PHK 86 5
DAPK1 90 3
CHK1 87 13
CHK2 72 10
GSK3 beta 90 6
CDK2-Cyclin A 92 8
CDK9-Cyclin T1 80 4
PLK1 94 13
Aurora A 91 6
Aurora B 86 9
TLK1 100 2
LKB1 95 12
AMPK 77 8
MARK1 105 20
MARK2 85 7
MARK3 93 2
MARK4 84 5
BRSK1 87 11
BRSK2 77 13
MELK 63 0
NUAK1 49 7
SIK2 105 14
SIK3 79 2
TSSK1 86 9
CK1 gamma 2 87 8
CK1 delta 57 0
CK2 77 4
TTBK1 83 10
DYRK1A 84 3
DYRK2 72 8
DYRK3 80 4
NEK2a 100 16
NEK6 87 2
IKK beta 74 1
IKK epsilon 94 17
TBK1 106 2
PIM1 89 8
PIM2 99 9
PIM3 83 10
SRPK1 84 10
EF2K 95 4
EIF2AK3 93 11
HIPK1 87 9
HIPK2 99 14
HIPK3 90 5
CLK2 88 19
PAK2 90 3
PAK4 78 7
PAK5 82 7
PAK6 96 1
MST2 72 12
MST3 82 2
MST4 79 3
GCK 73 0
MINK1 78 7
MEKK1 82 3
MLK1 88 1
MLK3 94 13
TESK1 93 8
TAO1 97 18
ASK1 91 13
TAK1 66 6
IRAK1 63 5
IRAK4 86 0
RIPK2 49 8
OSR1 91 10
TTK 65 11
MPSK1 101 17
WNK1 107 15
ULK1 67 0
ULK2 69 5
Src 50 7
Lck 92 10
CSK 93 1
YES1 39 9
ABL 86 7
BTK 80 12
JAK2 94 5
SYK 88 19
ZAP70 95 20
TIE2 98 14
BRK 75 8
EPH-A2 111 17
EPH-A4 80 10
EPH-B1 95 1
EPH-B2 97 11
EPH-B3 105 18
EPH-B4 98 15
FGF-R1 82 12
HER4 98 15
IGF-1R 87 5
IR 80 9
IRR 88 22
TrkA 92 2
DDR2 97 9
VEGFR1 53 7
Screening Concentration: 0.1µM
Kinase % Activity Remaining Standard Deviation
MKK1 107 6
MKK2 98 19
MKK6 100 12
ERK1 103 1
ERK2 110 15
JNK1 13 2
JNK2 87 21
JNK3 14 1
p38 alpha MAPK 105 2
p38 beta MAPK 90 7
p38 gamma MAPK 99 6
p38 delta MAPK 96 10
ERK8 90 4
RSK1 89 5
RSK2 82 2
PDK1 84 8
PKB alpha 102 6
PKB beta 99 11
SGK1 117 20
S6K1 98 4
PKA 105 14
ROCK 2 86 12
PRK2 112 9
PKC alpha 93 5
PKC gamma 92 6
PKC zeta 116 3
PKD1 99 15
STK33 99 16
MSK1 91 11
MNK1 86 27
MNK2 84 6
MAPKAP-K2 102 6
MAPKAP-K3 91 25
PRAK 92 10
CAMKK beta 133 24
CAMK1 92 1
SmMLCK 97 0
PHK 85 19
DAPK1 102 7
CHK1 102 19
CHK2 102 10
GSK3 beta 114 2
CDK2-Cyclin A 107 4
CDK9-Cyclin T1 85 18
PLK1 98 7
Aurora A 97 2
Aurora B 87 2
TLK1 99 5
LKB1 106 6
AMPK 101 12
MARK1 114 7
MARK2 99 4
MARK3 92 5
MARK4 101 16
BRSK1 99 8
BRSK2 87 7
MELK 91 3
NUAK1 79 10
SIK2 100 3
SIK3 88 1
TSSK1 91 7
CK1 gamma 2 109 6
CK1 delta 89 13
CK2 93 4
TTBK1 92 2
DYRK1A 98 0
DYRK2 73 0
DYRK3 94 6
NEK2a 105 9
NEK6 95 18
IKK beta 62 5
IKK epsilon 92 8
TBK1 100 20
PIM1 104 6
PIM2 104 9
PIM3 103 26
SRPK1 97 1
EF2K 98 6
EIF2AK3 103 6
HIPK1 103 19
HIPK2 92 10
HIPK3 97 3
CLK2 102 14
PAK2 99 9
PAK4 98 21
PAK5 100 7
PAK6 110 11
MST2 100 23
MST3 85 3
MST4 96 0
GCK 98 9
MINK1 94 6
MEKK1 95 17
MLK1 98 7
MLK3 95 0
TESK1 89 10
TAO1 124 5
ASK1 100 13
TAK1 90 5
IRAK1 93 18
IRAK4 88 24
RIPK2 82 4
OSR1 96 0
TTK 85 3
MPSK1 110 8
WNK1 102 3
ULK1 27 2
ULK2 28 4
Src 85 8
Lck 96 0
CSK 110 16
YES1 87 13
ABL 97 3
BTK 96 5
JAK2 100 2
SYK 103 10
ZAP70 105 10
TIE2 105 1
BRK 94 42
EPH-A2 118 13
EPH-A4 87 4
EPH-B1 97 4
EPH-B2 101 11
EPH-B3 112 20
EPH-B4 97 3
FGF-R1 103 6
HER4 102 5
IGF-1R 106 37
IR 102 9
IRR 93 1
TrkA 102 30
DDR2 106 5
VEGFR1 100 2

Do you need any help? Please get in touch and we’ll be happy to lend a hand.