Kinase Profiling Inhibitor Database

Inhibitor Structure Image Brutto MW Action Reference Reference 2 Patent Commercial Vendor Notes Results
JNKIN7 C28H27N7O2 493.56 JNK Zhang T. (2012) Chem Biol. 19(1) 140-54 Download

Results as Barchart

View results as a bar chart
1µM
0.1µM

Results as Table

Screening Concentration: 1µM
Kinase % Activity Remainingsort descending Standard Deviation
JNK1 4 1
IRAK1 5 0
JNK3 16 0
CLK2 18 5
JNK2 19 9
GCK 20 1
ERK8 20 8
VEGFR1 32 2
CK1 delta 33 0
CAMKK beta 35 4
TAK1 39 1
MLK1 39 0
RIPK2 42 1
CDK9-Cyclin T1 42 2
HIPK2 46 4
MELK 48 1
DYRK2 56 2
GSK3 beta 56 1
YES1 58 4
MLK3 59 8
IKK beta 63 2
ULK1 63 13
MST2 64 6
SIK3 64 12
IRR 64 6
PAK4 66 6
SIK2 67 7
MINK1 69 2
ULK2 69 7
ROCK 2 71 2
SYK 72 5
CDK2-Cyclin A 72 2
Src 72 10
CHK2 73 1
Aurora B 73 1
MARK3 76 2
BRSK2 76 6
JAK2 77 8
TTK 77 3
RSK1 77 31
IR 77 24
HIPK1 78 10
DYRK3 79 6
TBK1 79 11
TTBK1 79 8
MARK1 80 1
RSK2 80 4
BRK 81 16
CK2 81 10
TrkA 82 11
p38 beta MAPK 82 6
NUAK1 82 10
PKD1 82 9
PHK 83 0
MARK4 83 16
DAPK1 83 2
TIE2 84 15
PIM3 84 6
MNK2 84 21
MARK2 85 2
SmMLCK 85 1
ABL 85 12
PRAK 85 8
DYRK1A 85 6
BTK 85 14
BRSK1 86 6
EPH-B1 86 19
AMPK 87 4
IRAK4 88 6
CHK1 88 2
CK1 gamma 2 88 4
MKK6 91 0
PAK5 91 8
STK33 91 12
MSK1 91 6
LKB1 91 18
CAMK1 92 4
PRK2 92 3
PAK2 93 1
MST3 93 15
MNK1 95 23
FGF-R1 95 14
TAO1 95 20
NEK6 96 0
PKC alpha 97 8
Aurora A 97 3
IKK epsilon 98 8
PDK1 98 4
TLK1 98 8
TESK1 98 10
EIF2AK3 99 9
p38 delta MAPK 100 4
MEKK1 100 8
ASK1 100 1
PKC gamma 101 5
TSSK1 101 7
EF2K 101 1
Lck 101 1
MAPKAP-K3 101 4
HIPK3 101 22
PIM2 102 8
IGF-1R 102 8
MKK2 102 13
PAK6 103 8
MPSK1 103 8
PKC zeta 103 4
p38 gamma MAPK 103 0
EPH-B2 103 10
CSK 103 7
MST4 104 1
SRPK1 104 4
PKB alpha 104 5
SGK1 105 9
NEK2a 105 21
OSR1 105 7
EPH-A4 105 2
PLK1 106 1
HER4 106 7
MAPKAP-K2 106 11
PKB beta 106 18
DDR2 108 9
PKA 108 15
ERK1 109 9
EPH-B4 109 6
S6K1 112 4
p38 alpha MAPK 113 3
MKK1 113 9
ERK2 114 17
PIM1 114 6
WNK1 117 8
EPH-B3 118 20
ZAP70 123 1
EPH-A2 125 17
Screening Concentration: 0.1µM
Kinase % Activity Remainingsort descending Standard Deviation
JNK1 9 2
JNK3 15 2
CDK9-Cyclin T1 22 4
IRAK1 26 14
NUAK1 35 1
ULK1 37 1
GCK 45 4
ERK8 46 5
CLK2 49 2
ULK2 50 5
VEGFR1 59 4
CK1 delta 63 5
TAK1 67 4
MELK 71 0
MLK1 72 0
IRR 72 1
Aurora B 74 1
RIPK2 74 21
CHK1 74 17
IGF-1R 75 22
IKK beta 76 16
ABL 77 9
TBK1 77 5
LKB1 78 3
SIK2 78 1
MLK3 79 1
RSK2 80 11
CK2 80 1
YES1 80 17
IR 81 1
DYRK3 81 9
JNK2 81 8
BRK 81 11
SIK3 81 4
DYRK2 82 20
ZAP70 82 1
BRSK2 82 8
MST2 83 10
TTK 83 6
MNK1 84 16
PAK4 84 8
HIPK2 85 10
JAK2 85 10
MARK4 85 3
CDK2-Cyclin A 85 0
MEKK1 85 11
HIPK1 86 11
BTK 86 22
IRAK4 86 12
MKK2 87 19
CAMKK beta 87 10
CAMK1 87 12
PAK6 87 4
CK1 gamma 2 88 1
TTBK1 88 13
S6K1 88 2
NEK6 88 12
GSK3 beta 88 8
MSK1 88 9
TSSK1 88 3
PDK1 89 14
SYK 89 17
DDR2 89 7
ROCK 2 89 10
PAK5 89 1
PKC alpha 89 4
CHK2 89 2
EIF2AK3 90 2
TESK1 90 16
DAPK1 90 8
p38 gamma MAPK 90 10
MAPKAP-K2 91 1
MARK1 91 9
PLK1 91 9
MNK2 92 5
PKB alpha 92 5
AMPK 92 12
EPH-A4 92 5
STK33 92 8
MINK1 92 9
PKB beta 93 13
NEK2a 93 1
EPH-B1 93 9
Src 93 9
FGF-R1 94 19
MARK2 94 1
PHK 94 10
TIE2 94 5
BRSK1 94 4
MST3 94 3
RSK1 95 21
Lck 95 0
TAO1 96 1
PRAK 96 17
ASK1 96 9
TrkA 96 24
SmMLCK 96 6
PKC gamma 96 4
p38 beta MAPK 96 5
PIM2 96 8
EF2K 97 5
DYRK1A 97 2
MKK6 97 13
PKA 97 5
IKK epsilon 97 4
PIM1 97 3
PIM3 97 6
MKK1 98 6
p38 alpha MAPK 98 0
MST4 98 2
TLK1 99 7
ERK2 99 16
PRK2 99 0
OSR1 99 2
MARK3 101 5
EPH-B2 101 9
EPH-B3 101 6
PAK2 102 2
WNK1 103 17
MAPKAP-K3 104 9
SGK1 105 20
PKD1 105 37
SRPK1 105 16
EPH-B4 105 2
p38 delta MAPK 106 7
Aurora A 107 7
HER4 108 32
MPSK1 108 3
CSK 109 20
ERK1 110 16
EPH-A2 110 7
PKC zeta 112 3
HIPK3 113 0

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